Paeds Key Concepts Flashcards
If a newborn has hypoglycaemia in the hours after birth what should you do and why?
Transient hypoglycaemia in the first 24 hours is common
Asymptomatic - encourage normal feeding (breast/bottle), monitor blood glucose
Symptomatic - admit to neonatal unit and IV 10% dextrose
What are the key features of patent ductus arteriosus?
Left subclavicular thrill Continuous 'machinery' murmur Large volume, bounding, collapsing pulse Wide pulse pressure Heaving apex beat
How is patent ductus arteriosus managed?
Indomethacin or ibuprofen (inhibits prostaglandin synthesis and promotes duct closure)
What are the main features of acute lymphoblastic leukaemia?
Bone marrow failure
- anaemia (lethargy and pallor)
- neutropaenia (frequent/severe infections)
- thrombocytopaenia (easy bruising, petechiae)
Bone pain
Spleno/hepatomegaly
Fever (either representing infection or constitutional symptom)
Testicular swelling
What are main common sign + symptom of anaemia?
Soft systolic murmur
Shortness of breath on exertion
What is the management for whooping cough?
Azithromycin or clarithromycin if onset of cough within previous 21 days
What are the 3 phases of whooping cough?
Catarrhal (getting worse)
Paroxysmal (v bad)
Convalescent (getting better)
What are the main features of whooping cough?
Initial mild illness with coryzal symptoms, fever, mild cough that then progresses to clusters of lots of rapid coughs + long inspiratory effort + ‘whoop’ at end of cough clusters + cyanosis + vomiting (frequently post-cough cluster)
Unvaccinated kids
When are children usually vaccinated against whooping cough?
2, 3, 4 months
3-5 years
What is the management for croup?
A single immediate dose of oral dexamethasone (0.15mg/kg)
When do most children achieve day and night time continence?
3-4 years old
What is the management for noctural enuresis in children under 5?
Reassurance that this is normal and advice about fluid intake and encouraging to empty bladder regularly during day and before sleep
What 4 things should be recorded in all febrile children?
Temperature
HR
RR
Cap refill
What are the 3 risk classes for children with fever?
Green
Amber
Red
What is the management for green, amber, and red risk class febrile children?
Green - manage at home with appropriate care advice + when to seek more help
Amber - safety net advice (advice on warning symptoms/a follow-up appointment/liaison with other HCPs)
Red - refer child urgently to paediatric specialist
What are the 3 month motor development milestones?
Little or no head lag on being pulled to sit
Lying on abdomen, good head control
Held sitting, lumbar curve
What are the 6 month motor development milestones?
Lying on abdomen, arms extended Lying on back, lifts and grasps feet Pulls self to sitting Held sitting, back straight Rolls front to back
What is the 6-8 month motor development milestones?
Sits without support (refer at 12 months)
What are the 9 month motor development milestones?
Pulls to standing
Crawls
What are the 12 month motor development milestones?
Cruises
Walks with one hand held
What is the 13-15 month motor development milestone?
Walks unsupported (refer at 18 months)
What is the 18 month motor development milestone?
Squats to pick up a toy
What are the 2 years motor development milestones?
Runs
Walks upstairs and downstairs holding onto rail
What are the 3 years motor development milestones?
Rides a tricycle using pedals
Walks up stairs without holding onto rail
What is the 4 years motor development milestone?
Hops on one leg
When is neonatal hypoglycaemia severe enough to warrant admission and what do you do on admission?
- Symptomatic
- very low blood glucose (<1mmol/L)
IV 10% dextrose on admission
What is first-line treatment for idiopathic constipation in children?
Movicol Paediatric Plan (polyethylene glycol 3350 + electrolytes) on escalating dose regimen
What should you do if first-line treatment for idiopathic constipation in children does not lead to disimpaction within 2 weeks?
Stimulant laxative (senna)
What does short stature and primary amenorrhoea suggest?
Turner’s Syndrome
What is Turner’s Syndrome?
Primary amenorrhoea (amongst other issues) caused by presence of only 1 X chromosome or deletion of short arm of one of the X chromosomes
When a child lacks capacity, what consent is required to administer treatment if it’s in the best interests of the child?
Consent from one parent (as long as it’s in best interests)
When is jaundice always pathological in newborns?
In the first 24 hours
What are 4 causes of jaundice in the first 24 hours of life?
Rhesus haemolytic disease
ABO haemolytic disease
Hereditary spherocytosis
Glucose-6-phosphodehydrogenase
How does seborrhoeic dermatitis (cradle cap) usually present in children?
Erythematous rash + coarse yellow scales
V young child
How is seborrhoeic dermatitis managed?
Mild-moderate - baby shampoo and baby oils
Severe - mild topical steroids e.g. 1% hydrocortisone
What is the first sign of puberty in boys?
Increase in testicular volume
What does erythematous rash, poorly demarcated, and covering 10% of total body area with no history of common allergen contact or new skincare products + Hx of familial atopy suggest?
Atopic dermatitis (eczema)
When does idiopathic thrombocytopenic purpura need treated?
If platelets <10*10^9/L
OR
Significant bleeding
- otherwise it resolves 80% of the time within 6 months with/without treatment
How is Prader-Willi syndrome inherited?
Imprinting - Prader-Willi gene deleted from father
What are the murmur findings for ventricular septal defect?
Pansystolic murmur in lower left sternal border
What are the murmur findings for coarctation of the aorta?
Crescendo-decrescendo murmur in upper left sternal border
What are the murmur findings for patent ductus arteriosus?
Diastolic machinery murmur in the upper left sternal border
Ejection systolic murmur in the upper left sternal border
Pulmonary Stenosis
When are bow legs in a child normal and what is the management?
<3 years old
Usually resolves by 4 y/o so just reassure patients
What is the most common cause of primary headache in children?
Migraine
What are the features of hand, foot, and mouth disease?
Mild systemic upset
Oral ulcers
FOLLOWED by vesicles on palms and soles
How does congenital cytomegalovirus (passing of CMV from mum to baby during pregnancy) present?
Child with: Hearing loss Low birth weight Petechial rash Microcephaly Seizures
When can a child with scarlet fever return to school?
24 hours after commencing antibiotics
What are the presenting features of scarlet fever?
Blanching, red, punctate, rough sandpaper-like texture rash on torso
Fever, sore throat
Throat red with petechiae on hard and soft palate
Tongue covered in white coat + red papillae
What is the management of scarlet fever?
Oral penicillin V for 10 days (azithromycin in case of allergy)
Can return to school 24 hrs after starting abx
SF is a notifiable disease
Why should a child with limp/hip pain and fever be referred for same-day assessment?
Want to rule out septic arthritis due to poor outcomes
- likely to be transient synovitis but must make sure first
How should UTI in the 3 brackets of children be managed?
<3 months - Immediate referral to paediatrician
> 3 months upper UTI - consider admission, oral cephalosporin or co-amoxiclav for 7-10 days
> 3 months lower UTI - oral abx 3 days (trimethoprim, nitrofurantoin, cephalosporin, amoxicillin) + bring child back if still unwell after 24-48 hrs
Consider prophylactic abx if recurrent UTIs
What is plagiocephaly and what is the prognosis?
Skull deformity - unilateral occipital flattening due to campaign around prevent SIDS
Vast majority of children improve by age 3-5 due to adoption of upright posture. Can also put child on tummy in day, supervised supported sitting during day.
What is the characteristic presentation of measles?
Fever + myalgia + painful eyes
Conjunctivitis
Clusters of white lesions on buccal mucosa (Koplik spots)
Main risk factor for transient tachypnoea of the newborn
C-section (risk factor for?)
Transient tachypnoea of the newborn CXR appearance
Appearance on CXR
- Hyperinflation of the lungs
- Fluid in horizontal tissue
Threadworm treatment
Mebendazole single dose + hygiene advice/measures for whole household
Clinical features of ASD
Impaired social communication/interaction
Repetitive behaviours, interests, activities
Intellectual/language impairment
Management of ASD
Early educational/behavioural interventions (ABA, ASD preschool, TEACCH, ESDM, JASPER)
SSRIs - symptom relief for anxiety, aggression, repetitive behaviour
Antipsychotics - symptom relief for aggression, self-injury
Methylphenidate - ADHD
Family support/counselling
Causes of stridor in children
Croup - 6 months-3 years (+barking cough, fever, coryzal sx)
Acute epiglottitis - 2-6 years (+rapid onset, unwell/toxic child, drooling)
Inhaled FB - choking, coughing, vomiting
Laryngomalacia - congenital abnormality of larynx, 4-8 weeks
Normal basic obs for infants
RR 30-60
HR 100-160
T 37c
Turner’s syndrome complication –> crescendo/decrescendo murmur UR sternal border radiating carotids
Bicuspid aortic valve (complication of + description)
Investigations for developmental dysplasia of the hip (DDH)
Ultrasound
>4.5mths then X-ray
Risk factors for DDH
Female sex - 6x greater
Breech presentation
Routine US exam for infants in these categories
1st degree FHx of hip problems in early life
Breech presentation ≥36w gestation
Multiple pregnancy
Barlow test
Test that attempts to dislocate an articulated femoral head
- checks for DDH
Investigation for vesicoureteric reflux
Micturating cystourethrogram
≤3m old infant
Irritability, general lethargy, poor feeding, fevers +/- seizures.
Meningitis presentation in infants
Treatment for meningitis in children <3m
IV amoxicillin IV cefotaxime (cover Listeria)
Congenital diaphragmatic hernia prognostic factors
Liver position (liver in chest is bad) Lung-to-head ratio (estimates foetal lung size, >1.0 is good)
IV fluid resus amount in children/young people
20ml/kg over <10 mins (0.9% NaCl bolus)
Daily fluid calculation method in children
Maintenance = 100ml/kg for first 10kg, 50ml/kg for next 10kg, 40ml/kg for next 20kg
Replacement = 100ml/kg/day
Foetal alcohol syndrome key feature
Microcephaly (+/- smooth philtrum, hypoplastic upper lip, epicanthic folds)
Innocent murmurs in children characteristics
Characteristics
Soft-blowing murmur in pulmonary area Short buzzing murmur in aortic area May vary with posture Localised, no radiation No diastolic component No thrill No added sounds (e.g. clicks) Asymptomatic child No other abnormality
3 years to acquire tolerance
Common milestone to achieve milk tolerance (esp post-milk ladder)
Investigation used for diagnosis AND grading of severity in vesicoureteral reflux (a.k.a reflux nephropathy)
Micturating cystography
Red flag symptoms/signs in child with fever
Colour - Pale/mottled/ashen/blue
Activity - no response to social cues, appears ill to a HCP, doesn’t wake or doesn’t stay awake if roused, weak/high-pitched/continuous cry
Respiratory - grunting, RR >60, moderate/severe chest indrawing
Circulation or hydration - reduced skin turgor
Other - age <3m + temp ≥38. Non-blanching rash. Bulging fontanelle. Neck stiffness. Status epilepticus. Focal neurological signs. Focal seizures.
Definition + description of hypospadias + 2 associated conditiosn
Congenital abnormality of the penis - ventral urethral meatus, hooded prepuce, chordee (ventral curvature of penis) in more severe.
Associated with cryptorchidism (present in 10%) and inguinal hernia
Management of hypospadias
Refer to specialist services
Corrective surgery at 12 months, don’t circumcise before
If very distal don’t treat
Pulses to check in infant BLS
Brachial and femoral arteries
Pathogen for bronchiolitis
Respiratory synctial virus (RSV) (75-80%
Also mycoplasma, adenoviruses or secondary bacterial infection
Conditions likely to make bronchiolitis more severe
Bronchopulmonary dysplasia (e.g. if premature)
Congenital heart disease
CF
Examination findings for transposition of the great arteries
Loud single S2 sound
Prominent right ventricular impulse palpable
NO murmur
Pierre-Robin syndrome presentation
Baby with micrognathia (small lower jaw), posterior tongue, cleft palate with no FHx
Obese boy + groin/thigh/knee pain =
?slipped capital femoral epiphysis
Perthes’ disease prognosis if present <6y + management
Good prognosis <6y
Requires only observation
Course of action for unilateral undescended testicle
Review at 3 months
If persistent then refer
Indication for bone marrow exam in children with immune thrombocytopenia (ITP)
Only required if there are atypical features
Transposition of great arteries cyanotic or non-cyanotic?
Cyanotic
‘Tripod’ position + condition
Leaning forward with neck extended while seated
Acute epiglottitis
Ebstein’s anomaly findings on exam + Ix
Systolic murmur
Echo - right atrial hypertrophy + septal and posterior leaflet of the tricuspid valve attached to right ventricle
Management of unborn with exomphalos (intestine outside abdomen, developmental issue)
C-section to reduce risk of sac rupture
SpO2 readings expected from healthy neonate
Suboptimal SpO2 readings expected in first 10 mins of life (like 70% and above)
Chickenpox risk factor for what kind of soft tissue infections
Invasive group A strep soft tissue infections
including NECROTISING FASCIITIS
Commonest benign cause of noisy breathing in infants
Laryngomalacia
Treatment of uncomplicated transient tachypnoea of the newborn
Observation + supportive care +/- oxygen
Ventricular septal defect increases the risk of…
Endocarditis
What is fragile X syndrome?
A trinucleotide repeat disorder
Childhood disorders associated with fragile X syndrome
Learning difficulties
Autistic spectrum disorder
- particularly in males
Genetic anticipation definition
Hereditary diseases that have an earlier age of onset through successive generations
Types of hereditary disorders (+2 examples) that exhibit genetic anticipation
Trinucleotide repeat disorders
- Huntington’s disease
- Myotonic dystrophy
Differentiation between bronchiolitis and pneumonia in a child
Bronch - low-grade fever
Pneumonia - high-grade fever (>39) and/or persistently focal crackles
Head injury red flags for immediate CT in children
Loss of consciousness >5 mins Amnesia >5 mins Abnormal drowsiness 3+ vomits Suspected non-accidental injury Post-traumatic seizure without epilepsy GCS <14 Suspected open/depressed skull injury/tense fontanelle
How long can transient hypoglycaemia last in the newborn
First hours to days
Key risk factor for neonatal hypoglycaemia
Preterm birth (<37 wks)
Most common signs of neonatal sepsis
Grunting and other signs of respiratory distress
Hirschsprung’s disease diagnostic test
Rectal biopsy to examine under microscope for absence of ganglionic cells
Definition of Kawasaki’s disease
Fever for 5+ days with 4 of:
- dry cracked lips
- bilateral conjunctivitis
- peeling of skin on fingers and toes
- cervical lymphadenopathy
- red rash over trunk
Characteristic rash of systemic-onset juvenile idiopathic arthritis/Still’s disease
Salmon-pink
Passage of meconium normal time + red flag time (and associated condition)
Normally in first 24 hours
Red flag is >48 hours (delayed passage, Hirschsprung’s disease)
Large volume, bounding, collapsing pulse
Patent ductus arteriosus
Organism responsible for majority of croup cases
Parainfluenza virus
Boy with learning difficulties, extremely friendly + extroverted. Short for his age + supravalvular aortic stenosis
William’s syndrome
Poor prognostic factors for ALL
Presenting <2 or >10 years
Having B or T cell surface markers
Having WCC >20x10^9/L at diagnosis
Male
Treatment of pyloric stenosis
Ramstedt pyloromyotomy
Investigation for stable children ?Meckel’s diverticulum
Technetium scan
Episodic hypercyanotic spells sometimes resulting in loss of consciousness in infants - name of spells + condition associated
‘tet’ spells
Tetralogy of Fallot
Don’t do this on examination of croup patient
Don’t do THROAT examination - airway obstruction risk (also in acute epiglottitis)
Next management step in 5-16y with asthma not controlled by SABA (salbutamol)
Add low-dose corticosteroid inhaler (beclometasone)
Paediatric basic life support ratio of chest compressions to rescue breaths
15:2
Chickenpox school exclusion protocol
Exclude until:
- lesions are dry
- lesions have crusted over (usually about 5 days after rash onset)
Major complication of Kawasaki disease + investigation
Coronary artery aneurysm
- echocardiogram
Inheritance chance of autosomal dominant disease if 1 parent has it and other parent doesn’t have it
50%
Asthma in child <5 not controlled with SABA and low-dose ICS - next step?
Add leukotriene receptor antagonist (montelukast)
Asthma not controlled by SABA, ICS, leukotriene receptor antagonist - next step?
Stop leukotriene receptor antagonist Add LABA (long-acting beta-agonist)
Management of VZV exposure if immunosuppressed
VZIG
Causes of snoring in children
Obesity Nasal problems Recurrent tonsillitis Down's Hypothyroidism
What is Kallman’s syndrome
Delayed puberty secondary to hypogonadotrophic hypogonadism
Management step after general advice and rewards systems
Enuresis alarm
Management of DDH
Most spontaneously stabilise by 3-6 wks
Pavlik harness if <4-5 mths
Older children may require surgery
Pavlik harness description
Dynamic flexion-abduction orthosis
Test if neonate has abnormal hearing test at birth
Offered auditory brainstem response test as a newborn/infant
Investigation of choice in ?intussusception
Ultrasound
Pain in legs with no obvious cause or worrying features. Diagnosis?
Growing pains
Management of appendicitis
Appendicectomy
Management of necrotising enterocolitis
Medical management
Laparotomy if deteriorates
Management of intussusception
Pneumatic reduction under fluoroscopic guidance
Most common childhood leukaemia + triad of presenting symptoms/signs
Acute lymphoblastic leukaemia
Anaemia + neutropenia + thrombocytopenia
Management of exomphalos vs gastroschisis
Exomphalos - gradual repair (staged closure starting immediately with completion at 6-12 mths)
Gastroschisis - URGENT correction required
Achondroplasia inheritance pattern + outcomes for potential children
Autosomal dominant
25% normal
50% affected heterozygous
25% affected homozygous (die in first months)
Investigation for ?slipped upper femoral epiphysis
Hip x-ray
Investigation for ?DDH
US hip
?Perthe’s disease investigation
MRI scan
When should parents call an ambulance in the event of a febrile child’s seizure
If convulsion (febrile remember) lasts >5 MINS
Hirschsprung’s disease management
Rectal washouts/bowel irrigation
Neurological disease Down syndrome associated with later in life
Alzheimer’s disease
Management of umbilical hernias in children
Usually self-resolve
If large + symptomatic = elective repair at 2-3 y/o
If small + asymptomatic = elective repair at 4-5 y/o