Paeds Flashcards
What fluid type is used for maintenance?
Bolus?
Neonates?
0.9% NaCl + 5% glucose.
Bolus: just 0.9% NaCl
10% glucose solution.
How much is given as a bolus normally, and in DKA?
Normally 20mL/kg, DKA = 10mL/kg.
List the tests screened on the Guthrie heel prick.
- CF.
- Sickle cell disease.
- Congenital hypothyroidism.
- Phenylketonuria.
- MCADD.
- MSUD.
- IVA.
- GA1.
- HCU.
List the components of a paediatric septic screen.
- Bloods.
- Cultures.
- Urine culture.
- Stool culture.
- CXR.
- LP.
What is the prophylaxis for meningitis in household contacts?
Oral Rifampicin or Ciprofloxacin.
Sx and Tx for:
Otitis externa.
Otitis media.
Otitis media with effusion.
Inflamed ear canal +/- oedema and discharge.
Gentamycin and hydrocortisone topical.
Red and bulging tympanic membrane.
Amoxicillin.
Fluid level. Speech/language delay due to hearing issues.
Grommets.
What does a bilateral ‘ground glass’ appearance on CXR in a neonate suggest?
RDS.
What are 4 features of RDS and how long after birth do they present?
4 hours after birth:
- > 60 breaths/min.
- Sternal/subcostal recession, nasal flaring.
- Expiratory grunts.
- Cyanosis if severe.
When would resus in RDS not be attempted?
A baby <24 weeks.
Describe the Tx pathway for RDS
- Face mask with oxygen.
- CPAP (nasal canula.)
- Intubation.
- Add artificial surfactant if need invasive ventilation.
What are 4 common causes of RDS in term babies?
- Transient tachypnoea of the newborn.
- Meconium aspiration.
- Spontaneous pneumothorax.
- Milk aspiration.
Causative organism of acute epiglottitis?
Clinical features?
Ix?
Mx?
- Haemophilus influenzae b.
- Acute stridor, muffled cry, absent/quiet cough, toxic looking child, tripoding, drooling.
- DO NOT examine throat.
Ask about Hib vaccination. - Keep child relaxed and calm, and call immediately for anaesthetist to intubate.
What are the infective and non-infective causes of stridor?
Infective: croup, epiglottitis, bacterial tracheitis.
Non-infective: aspiration, laryngomalacia, anaphylaxis.
Causative organism of croup?
Clinical features?
Ix?
Mx?
Parainfluenza.
Peak age 2.
Preceded by coryza.
Cough: barking, seal life, paroxysmal, worse at night. Stridor.
Rule out epiglottitis, don’t examine throat in case it is that.
Oral dexamethasone.
Commonest causative organism of pneumonia?
Clinical features?
Ix?
Mx?
S. pneumoniae.
Cough, fever, tachypnoea, resp Sx.
Course crackles.
CXR - consolidation.
Treat as sepsis:
- CXR, Bloods MC&S, FBC, sputum culture, throat swabs, PCR (viral.)
Neonates: broad spectrum Abx.
Older: Amoxicillin (2nd line erythromycin.)
Commonest causative organism of bronchiolitis?
Clinical features?
Ix and reason for admission?
Mx?
Respiratory syncytial virus.
> 1 year.
Winter months.
Coryza, dry cough peaks at day 4/5.
High threshold for Ix.
<1/2 of usual feeds, resp distress, low sats (<92%)
Conservative: fluids and oxygen.
What is the prevention for RSV infection and who is it given to?
IM Palivizumab.
High risk:
- preterm.
- CF.
- Congenital cardiac conditions.
Causative organism of Whooping Cough?
Clinical features?
Ix?
Mx?
Prevention in pregnancy?
Bordetella pertussis.
Week of coryza, then:
- cough: worse at night, ends in vomiting, causes cyanosis.
- Inspiratory whoop.
- 10-14 weeks of Sx.
Nasal swab (PCR and serology.)
<6/12 = admit. IS A NOTIFIABLE DISEASE. Oral macrolide (mycins) if cough started within previous 21 days
Household contact prophylaxis.
Offered vaccine at 16 weeks in pregnancy.
Differentials for a wheeze?
- Viral induced wheeze.
- Asthma.
What is seen on examination is asthma?
Harrison sulci.
Wheeze.
Hyperinflated chest.
What is the PFR in a moderate, severe, and life-threatening asthma attack?
> 50%, <50%, <33%.
What are the features of a life-threatening asthma attack?
Silent chest. Poor resp effort. Altered consciousness. Cyanosis. Sats <92%. PEFR <33%. CO2 normal, if raised = near fatal.
What is the management of an acute asthma attack?
- Sats <94%, give high flow oxygen.
- Up to 10 puffs of SABA via spacer.
- Addition of nebulised SAMA.
- Oral pred for 3 days/IV hydrocortisone.
Asthma management pathway in children over 5.
- SABA.
- Next step/newly diagnosed with >/=3 Sx a week/waking at night: SABA + low dose ICS.
- LTRA.
- LABA (stop LTRA if didn’t help, or keep if it did.)
- SABA + low dose ICS MART
- SABA + moderate dose ICS MART/ moderate dose ICS with LABA.
- SABA + high dose ICS (fixed or in MART), trial theophylline.
Refer.
Asthma management pathway in children under 5.
- SABA.
- Next step/newly diagnosed with >/=3 Sx a week/waking at night: SABA + moderate dose ICS trial for 8 weeks.
- Not resolved: alternative Dx.
- Resolved then recurred in 4 weeks: restart low dose ICS.
- Resolved then recurred in >4 weeks: repeat 8 week trial. - SABA + low dose ICS + LTRA.
- Stop LTRA and refer.
Diagnostic criteria for asthma with spirometry.
FEV1:FVC ratio <70% and >12% increase in PF after SABA.
Type of genetic disorder in CF?
Clinical Fx?
Ix?
Mx for neonatal issues, resp, nutritional, and stage?
Autosomal recessive.
- Salt baby.
- Meconium ileus.
- Recurrent chest infections.
- Poor growth.
- Male infertility.
- Steatorrhea.
- Persistent, loose cough, purulent mucus, hyperinflation of chest, crepitations and wheeze, clubbing.
1st line: sweat test.
Confirmation - genetic.
Meconium ileus: enema, surgery.
Resp: prophylactic Abx, rescue Abx. Older = spirometry. BD physio.
Pancreatic enzyme replacement, high calorie, high fat diet, DM control.
Bilateral lung transplant for end stage.
Ix for coeliac disease?
IgA tissue transglutaminase (IgA-tTG)
Jejunal biopsy - villous atrophy.
What is the 1st and 2nd line Tx for CMPA
Switch to extensive hydrolysed formula.
Try amino-acid based formula.
What are the 2 different types of food allergy and how are they different?
IgE mediated; immediate response.
Non-IgE mediated: delayed (>48hr) response.
A child presents with abdominal pain and enlarged cervical lymph nodes with a PMHx of resp tract infection. What’s the likely diagnosis?
Mesenteric adenitis.
What are the types of dehydration that can present in gastroenteritis? What do they lead to?
Isonatraemic: total body deficit of water AND sodium.
Hyponatraemic: drink lots of water, so net loss of sodium. Leads to movement of fluid from extra to intracellular compartments = brain swelling.
Hypernatraemic: water loss exceeds sodium loss (rare) i.e. fever or dry environment. Shifts from intra to extracellular compartments = brain shrinking.
Ix and Mx of gastroenteritis
If unwell and blood, no improvement after 7 days = culture stool.
No dehydration: prevent with oral rehydration solution (ORS.)
Clinical dehydration: ORS and maintenance fluids.
Shock: bolus.
Common complication after recoerving from gastroenteritis? Tx?
Post-gastroenteritis syndrome: temporary lactose intolerance.
ORS for 24 hours and avoid lactose for a few weeks.