Paeds Flashcards

1
Q

Diagnosing T1DM in a child

A

Fasting glucose >/= 7
*Random blood glucose >/= 11.1
HbA1c >/= 48

Extra:
Blood pH to exclude DKA
Diabetes antibodies
U&Es
Autoimmune screen
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

1st presentation of T1DM1 management

Immediate

+

Long term

A

SAME DAY MDT paediatric diabetes team
Insluin ASAP

Admission for education + support

1) Insulin therapy: technique, dose adjustment
2) Nutritional: Complex carb high, <30% fat, 15-20% protein, refined sugar <25%
3) Monitoring of glucose: 4 x per day

Regualar management

  • Avoid hypos
  • Manage acute illness and avoid DKA
  • Screen for micro and macrovascular complciations

Insulin need varies with age

Ongoing integrated package of care by MDT diabetes team
24 access to the team
Home-based care with support from local paediatric diabetes team
Initial inpatient management IF:
< 2 years
social/emotional factors
Home very far from hospital
Liase with school staff + education etc etc
Record details on Diabetes Register

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Hypoglycaemia signs + cut off

Treatment

A

<4 blood glucose

Symptoms:
Hungry, dizzy, tummyache, faint, wobbly, progression to coma and seizures

Frequent episodes equals losing awareness of symptoms

Treating hypo
Early: sugary drinks or glucose tablet. Buccal if child unco-operative
Severe: glucagon injection kit if reduced consciousness (IM)
Unconscious: hospital to treat with IV glucose

After treatment biscuit/sandwich to prevent drop again

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

DKA management

A

Blood pH <7.3 + blood glucose >11.1, bicarb <15, capillary ketones >3mmol/l

A: Airway if coma. NGT if vom or coma
B: 100% oxgen face mask
C: Iv cannula, take bloods
- if shocked - 10ml/kg 0.9% saline bolus (Discuss more with consultant)
Diagnosis confirmation
Investigations: Blood glucose, Na, Cl, Ur, Cr, venous/cap blood gas

FLUIDS = requirement = deficit + maintenance
- Deficit 5% if ph>/= 7.1. 10% if <7.1.
- Maintenance if <10kg (2ml/kg/h), 10-40 (1ml/kg/h), more (fixed 40ml/hr)
FLUID = 0.9% NaCl (with 20 mmol/l KCl per 500ml)

Hourly rate = (10 x deficit/48) + maintenence/hour

BUT subtract boluses if >20ml/kg given before dividing

INSLUIN 1-2h after beginning IV fluid therapy
(dose 0.05-0.1 units/kg/hr)

Hourly monitoring: Cap glucose, fluid balance, GCS, vital signs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

DKA risk

A

Cerebral oedema
Hypokalaemia
Aspiration pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

T1DM follow up

A
4 x per year
Regular dental
Optician every 2 years
Autoimmune screening
Carry bracelet
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Hypothyroid congenital vs acquired presentation

A
Congenital
Usually asymptomatic and picked up on screening
– faltering growth 
– feeding problems
 – prolonged jaundice
– prolonged jaundice
– constipation along
– horse cry
– delayed development
– constipation along 
– hoarse cry 
– Congenital abnormalities e.g. heart defects

Acquired
SHORT STATURE
Classic
Females more than males

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Why does neonatal hyperthyroidism occur

A

In infants of mothers with thyrotoxicosis from transplacental transfer of auntie TSH receptor antibodies – requires treatment as fatal but resolved with regression of maternal antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

CAH diagnosis

Presentation

A

Diagnosis

  • 17-a-hydroxyprogesterone elevated for classical deficiency in 21 alpha hydroxylase
  • 11-deoxycortisol if beta hydroxylase deficiency
DO blood gase
\+ U&amp;Es
Genetic analysis
Urinary steroids
Pelvic and adrenal US for ambiguous genetalia at birth

Presentation

  • F: At birth, virilisation
  • M: salt losing crisis in the 80% that are salt loser ~ 1-3 weeks old = vom, weight loss, hypotonia, FTT
  • -> Hypotension, hyponatraemia, hyperkalaemia, metabolic acidosis

Later features = Precocious puberty + final height below expected

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Delayed puberty in female tests

A

Unlikely to be constitutional so do

  • karyotyping
  • TFTs
  • Sex steroid hormones
  • Consider eating disorder and pituitary pathology
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Precocious puberty girl ultrasound

A

Uterus goes from tubular to pear shaped and can identify endometrial lining near menarche

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Males causes of precocious puberty and how to differentiate

A

Differentiate based on testicular size
Bilateral enlargement (>l4m) = GDPP
Prepubertal testes = GIPP e.g. Adrenal tumour/CAH
Unilateral enlargement equals gonadal tumour

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Normal puberty males

A

First sign is testicular growth at around 12 years of age (range = 10-15 years)
testicular volume > 4 ml indicates onset of puberty
maximum height spurt at 14

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Normal puberty girls

A

first sign is breast development at around 11.5 years of age (range = 9-13 years)
Height spurt reaches its maximum early in puberty (at 12) , before menarche
Menarche at 13 (11-15)
Increase of only about 4% of height following menarche

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Precocious puberty males

A

Secondary sexual characteristics <9

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Precocious puberty causes (broadly)

A
  1. Gonadotrophin dependent (‘central’, ‘true’)
    Due to premature activation of the hypothalamic-pituitary-gonadal axis
    FSH & LH raised
  2. Gonadotrophin independent (‘pseudo’, ‘false’)
    due to excess sex hormones
    FSH & LH low
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Thelarche

A

Premature breast development
Typically between six months to 2 years
Rarely be on stage three puberty
Non-progressive and self-limiting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Adrenarche

A

Premature appearance of androgen dependent secondary sexual hair development acne and exhilarate odour

  • Less than eight years in females
  • Less than nine years in males
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Causes of HIE

Biochem picture

A

[1] fail of gas exchange across the placenta - abruption, uterine rupture, excess contactions
[2] Interruption of umbilical bloodflow - prolapse, compressionl
[3] Inadequate placental profusion perfusion - PET, HTN
[4] Compromised fetus - IUGR, anaemia

Hyperoxia hypercarbia metabolic acidosis
Due to cardiorespiratory depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Classification of H I E

How to diagnose

A

Mild: hyperventilation, hypertonia, Impaired feeding, responds excessively to stimulation
Moderate: movement abnormalities, hypotonic, cannot feed,? Seizures
Severe: no spontaneously response to pain, tone fluctuates, prolonged seizures, multi organ failure

Diagnosis needs
- Asses for intrapartum problen (e.g. CTG, prolapse)
– Resp depression at birth + need to resuscitate (Five minute Apgar <5)
– ACIDOSIS soon after birth (pH less than 7.0)
– Encephalopathy within 24 hours of birth
– Other causes of encephalopathy excluded

Management
- Resp suppor, AVOID HYPERTHERMIA (33-34 degrees best), fluid restrict, treat hypotension, monitor electrolytes and glucose, CFAM

Prognosis

  • Mild - expect full recovery
  • Moderate and feeding by 2 weeks = good prognosis
  • Abnormalities persiting beyond 2 weeks = unlikely recovery

30% mortality if severe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is PVL

A

Periventricular white matter lesions - echogencity, cysts = diagnosis on cranial US or MRI
- Due to severe HIE, poor cerebral perfusion, ischaemia, inflammation

Risk factors
Extreme prematurity
Hypertension
Severely ill
Hypercarbia

Prognosis
CP - SPASTIC DIPLEGIA LIKELY

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Define with cause

Caput secuccedaneum

Cephalhaematoma

Chignon

A

Caput secuccedaneum

  • Bruising and oedema of presenting part
  • ACROSS SUTURE LINES
  • above periosteum
  • Resolves in a few days

Cephalhaematoma

  • Haematoma from bleed below periosteum
  • Condfined so doesn’t cross sutures
  • Centre feels soft
  • Resolves over several weeks

Chignon
- Oedema and brusing from Ventouse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Respiratory distress syndrome

Risk factors

Cause

Presentation

Management
- Oxygen sats to aim for and why

A

Risk factors

  • PREMATURITY
  • Male
  • C-section
  • 2nd of premature twins
  • Diabetic mum?

Cause
- Surfactant deficiency –> alveolar collapse + inadequate gas exchange

Presentation

  • WITHIN 4h
  • Tachypnoea >60, Recession, nasal flaring, expiratory grunting, cyanosis if severe
Management
- Oxygen (21-30%)
--> 91% to 95%
<91% = NEC + DEATH risk
>95% = ROP

May need surfactant therapy or additional resp support

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Prematurity pneumothorax causes

Symptoms

Diagnosis

Management

A

1) Premature (RDS)
2) Meconium aspiration
3) Pulmonary hypoplasia
4) Pneumonia
5) TTN
6) Mechanical ventilation

Clinical picture
- Reduced breath sounds and chest movement on affected side

Dx: Transillumination with fibre optic light

Management

  • Chest drain if tension
  • Otherwise resolves alone
  • prevent with lowest pressure ventilaton
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Causes of feeding difficulties/ weight loss >10% of newborn Tongue... tell me more
Inexperienced mum Tongue tie (ankyloglossia) - M>F. Short lingual frenulum - Symptoms - difficulty attaching/staying attached, unsettled, hungry all the time, clicking sound as they feed - Management: nil if no feeding problems else tongue tie division (no anaesthetic if baby :O) - Later if speech difficulties or feeding continues, same procedure but GA and stitches
26
``` Left subclavicular thrill Continuous murmur Bounding collapsing pulse Wide pulse pressure Heaving apex beat ``` Diagnosis Risk factors Management
Diagnosis - PDA Risk factors - Congenital rubella - Premature - Born at high altitude Echo to diagnose Management if symptomatic - Prostaglandin synthetase inhibitor e.g. INDOMETHACIn or IBUPROFEN to close duct
27
NEC clinical picture cause Characteristic findings
1st few weeks ``` Clinical picture – sudden change in feeding – vomiting (maybe be bile stained) – distended abdomen – store may have blood (fresh) ``` Cause Bowel vulnerable to ischaemic injury and bacterial invasion in preterm infants – can perforate --> Leaking into abdomen ``` Characteristic findings – Dilated bowel loops – bowel wall oedema and thumbprinting – Pneumastosis intestinalis (intramural gas) – If severe pneumoperitoneum ``` Management STOP ORAL FEED AND GIVE BROAD ANTIBIOTICS – Rest bowl – energy to dream stomach, IV fluids and medicine – surgery if perforation Prognosis Mortality of 20%
28
Newborn hypoglycaemia management
If 2 readings <2.6 inspite adequate feeds or 1 v low (<1.6) or symptoms - IV glucose to maintain above 2.6
29
Jaundice risk factors Tests to do
Sibling needing food therapy Premature low-birth-weight Exclusively breastfeeding Jaundice in lesson 24 hours Tests <24h needs serum bilirubin in <2h 24h-2weeks needs serum bilirubin in <6h if TC reading >250 ``` And other tests for less than 24 hours – blood group (mum and baby) – DAT – blood packed for volume – FBC, blood Film – G6PD levels – microbiology (blood you're in CFF if needed) ```
30
What is Kernicterus Presentation Long term sequelae
Deposition of unconj bilirubin in basal ganglia and brainstem Presentation - Unstable - Opisthotonus - Seizures - Coma Long term sequelae - DYSKINETIC CP - LD - Sensorineural deafness
31
Biliary atresia
Progressive fibrosis and obliteration of extra and intra hepatic biliary tree --> leads to liver fibrosis failure and death within two years Aetiology unknown Mild jaundice, Pale stools and dark urine and faltering growth ``` Diagnosis Increase conjugated bilirubin is PT, INR (INR may be raised) Pepsi LFTs: GGT hight Ultrasound GOLD STANDARD = ERCP (lack of patency) WITH LIVER BIOPSY ``` Management KASAI - same time as ERCP = Hepatoportoenterostomy + Ursodeoxycholic acid
32
Low galactose 2 phosphate uridyl transferase on baby bloods Diagnosis Presentation Treatment
Galactossoemia - can't metabolise galactose --> identify in urine Dx is low enzyme levels on blood Features: Poor fed, vom, jaundice, heatomegaly Treatment - no lactose
33
Alpha 1 antitrypsin deficiency Diagnosis
Diagnosis - <20 alpha -1 antitrypsin in plasma Accumulation of protein in hepatocytes --> prolonged jaundice and bleeding due to vit K deficiency Autosomal recessive
34
TTN
Delay in absorption of long fluid More common after Caesarean Chest x-ray make show fluid in horizontal Fissure Usually settles within one day
35
When to suspect meconium aspiration Management
Late born babies Management only needed if respiration not established in 1 min Complications Airleak leading to pneumothorax and pneumomediastinum
36
Newborn pneumonia predisposing factors Management
1. prolonged rupture of membranes 2. chorioamnionitis 3. low-birth-weight Management Broad-spectrum antibiotics
37
Newborn pneumothorax predisposing factors
1. meconium aspiration 2. respiratory distress syndrome 3. complication of mechanical ventilation
38
Persistent pulmonary hypertension of the newborn Associations Presentation
``` Birth asphyxia Meconium aspiration Septicaemia Respiratory distress syndrome Fluoxetine in 3rd trimester ``` Presentation – Cyanosis soon after birth Diagnosis: chest x-ray normal heart size – urgent echo to exclude congenital heart disease and identify signs of raised pulmonary hypertension
39
Newborn coughing and choking when fed Possible cyanotic episodes Aspiration into lungs
Oesophageal atresia - Associated with polyhdramnios - Associated with oesophageal-tracheal fistula - Absent stomach bubble on antenatal US MUST SUCTION + surgery
40
What is port wine stain
Present from birth and usually grows with infant - Vascular malformationin capillaries in dermis - May be associated with Sturge Webber - Disfiguring lesions can be treated with laser
41
What is strawberry naevi
Cavernous hemangioma Usually not present at birth but appear in first month of life More common in preterm infants – increase in size until 3 to 15 months then regress – ulceration or haemorrhage maker – no treatment if small, topical propanolol may speed regression
42
DDH Risk factors Describe the tests
``` Female Breach History First born Oligohydramnios ``` Barlow: Attempt to dislocate an articulated femoral head - adduction of hip with posterior force on knee Ortalani: Attempts to re-locate a dislocated family head - Abduct hip with anterior force on femur US ALL BREECH BABIES at 6 weeks X-ray if >4.5months Management - Usually stabilise by 3-6 weeks spontaneously - Pelvic harness if <4-5months - Older children may require surgery
43
Croup Presentation Management
6m - 6yrs. Peak ~ 2yo Viral - mostly parainfluenza ``` Starts with coryzal symptoms Stridor Barking cough Worse at night Hoarseness Variable difficulty breathing system include cyanosis, LOC, stridor, air entry, ``` Management depends on severity - scoring 1) Mild = no stridor at rest - Oral single dose dexamethasone. Can go home 2) Moderate = stridor at rest; no agitation/lethary - Oral single dose dexamethasone + Nebulised adrenaline - Admit 3) Severe = stridor at rest; agitation/lethary - Oral single dose dexamethasone + Nebulised adrenaline - High flow O2 - Admit
44
Laryngomalacia Define Risk factors
Congenital abnormality of larynx cartilage – predisposes to supraglottic collapse during inspiration – intermittent upper airway obstruction and strider ``` Risk factors – GORD – neurological – male – Genetics e.g. Down's syndrome ``` Usually resolves by 12 to 24 months Management – observe and treat GORD if mild – endoscopic supraglottoplasty if severe – tracheostomy is possible
45
Indication to admit a child with respiratory problems
``` Apnoea Saturation is less than 92% on air Fluid intake reduced (75% of usual) Severe Respiratory distress – Grunting – marked chest recession – respiratory rate greater than 70 ```
46
Bronchiolitis Presentation causative organism
``` Dry wheezy cough Tachypnoea tachycardia Subcostal and intercostal recession Hyperinflation of the chest (liver displaced) Fine and inspiratory crackles High-pitched wheeze (expitatory mostly) ``` RSV
47
Whooping cough (pertusis) Presentation Risk factors Complications Diagnosis Management
[1] A week of coryza (catarrhal phase) ``` [2] Characteristic paroxysmal or spasmodic cough followed by inspiratory whoop (paroxysmal phase). Lasts up to 3 months what the F – Worse at night – may vomit – go red or blue in the face – mucus from nose and mouth EPISTAXIS AND CONJUNCTIVAL HAEMORRHAGE ``` [3] SymptomsDecrease (convalescent phase) Risk factors – less than six months old – lack of Vaccine – contact ``` Complications – pneumonia – seizures – bronchiectasis Rare to get complications ``` Diagnosis – I need a swab (identification of Bordetella pertussis) – PCR: more sensitive – FBC: Marked lymphocytosis over 15 Management Admit and isolate if paroxysms of face Antibiotics only work if started in catarrhal phase. ONLY GIVE IN 1st 21 days <1 month old: seven days clarithromycin >1 month old: azithromycin or clarithromycin SCHOOL EXCLUSION – Until 48 hours of antibiotics – for 21 days after onset of symptoms if not treated VACCINATE THE DAMN CHILD AFTER + PH ENGLANDfvs
48
Indications for tonsillectomy
``` Recurrent episodes of tonsillitis Peritonsillar abscess (Quincy) Obstructive sleep apnoea (Remove adenoids to) ```
49
Cystic fibrosis | pathology
Carrier rate: One in 25 Incidence: one and 2500 Live births Autosomal recessive Defect in the CF transmembrane conductance regulator (CFTR) – CFTR = cAMP Dependent Chloride channel Found in cells that line the lungs, Intestine, pancreatic duct, sweat glands, reproductive organs – CFTR gene is on chromosome 7 – Main mutation (78%) = deltaF508 Results in abnormal Ion transport – Airway: reduced hourly service liquid layer, impaired celery function, retention of mucopurulent secretions – Dysregulation of inflammation – Interestine: Thick viscous meconium --> Meconium ileus in 10 to 20% – Pancreatic duct: blocked my fix secretions --> Pancreatic enzyme deficiency and malabsorption – Sweat glands –: XS sodium and chloride in sweat
50
Cystic fibrosis diagnosis management
Newborn screen: IRT – IRT high --> screened for common gene mutations – If two mutations, sweat test To diagnose >60 Set test: low voltage current to pilocarpine applied to skin – sweat collected – Then confirm with gene abnormalities NB: normal sweat test: Cl = 10-40 Also low faecal elastase Faltering growth Steatorrhoea Management ALWAYS MDT - specialist cystic fibrosis centre: physio, nurses, dieticians – Physiotherapy at least twice a day to clear the Airway, regular nebulised hypertonic saline to decrease secretions – Continuous prophylactic oral antibiotics (flucloxacillin) Plus additional rescue – Pancreatic enzymes with all meals plus high calorie diet plus fat soluble vitamin supplements weekly in their first month of life - every 4 weeks when they are between 1 and 12 months old - every 6 to 8 weeks when they are between 1 and 5 years old - every 8 to 12 weeks when they are over 5 years - old every 3 to 6 months as adults
51
Long-term picture with cystic fibrosis
Newborn – screening – meconium alias ``` Infancy – prolonged jaundice – growth filtering – recurrent chest infection – malabsorption, steatorrhoea ``` Young child – bronchiectasis – rectal prolapse – nasal polyps – sinusitis All the child/adolescent – allergic bronchopulmonary aspergillosis – DIABETES MELLITUS - check from age 10 – liver cirrhosis and portal hypertension – distal intestinal obstruction (basically Maconi wireless) – pneumothorax – STERILITY IN MALES (absence of vas deferens)
52
Asthma management stepwise
[1] Diagnosis and assessment = SABA prn [2] Using SABA 3 or more times a week = + ICS v low dose [3] Control still poor 5yo or more = + LABA <5yo = + LTRA [4] Control still poor in 5yo or more Partial LABA response = + Increase ICS dose to low No LABA response = STOP LABA + Increase ICS dose to low [5] Control still poor. Consider - Increase ICS dose to moderate - Addition of theophylinne REFER TO SPECIALIST [6] Consider oral steroids
53
Hirschsprung's disease Cause Where is the junction Association Presentation
Failure of ganglion cells to migrate into hindgut = Absence of coordinated pal peristalsis an OBSTRUCTION is at the junction between normal bowel distal aganglionic bowel 80%: transition zone in rectum/sigmoid = short segement disease 20%: entire colon is involved = Long segment disease ``` Presentation – Usually first few days of life with lower intestinal obstruction 1. bile stained vomiting 2. .abdominal distension 3. failure to pass meconium ``` OCCASIONALLY CHILD PRESENTS with short segment disease and constipation - Associated with trisomy 21
54
Investigation of Hirschsprung's Disease Management Outcome
AXR: Obstruction but NOT SPECIFIC CONTRAST ENEMA: Shows location of transition soon. Most valuable initial screening diagnostic test Rectal biopsy: no ganglionic cells in submucosa Initial management – Bowel irrigation/rectal washout Surgical treatment – single stage pull through Outcome – 5% get normal bowel control – 15 to 20% have partial control – 5% never gain control (may have permanent stoma) ENTEROCOLITIS = worst complication. 10% mortality
55
Threadworm infection Presentation Management
Perry anal itching, with at night, associated with insomnia No systemic symptoms Very infectious Diagnosis is adhesive tape - Three consecutive days. Examination for eggs or adult worms Management For all patients and family members – Single oral dose: Mebendazole + HYGIENE May need repeat dose in 2weeks
56
Childhood constipation red flags
``` Lack of meconium within 48 hours of birth Failure to thrive/growth problems Abdominal distension Lower limb weakness Perianal bruising or multiple fishes ```
57
Childhood constipation diagnosis
– <3 complete stores in a week – overflow soiling (greater than one year old) = v smelly, loose, no sensation – distress or Straining – reduced appetite that improves on passing store – history of constipation – history of anal fisher
58
Causes of constipation
Mainly idiopathic – low fibre diet – lack of ability to exercise – family history and ``` GI – hash brown disease – anal disease – coeliac – partial obstruction – food hypersensitivity ``` ``` Non-GI – Hypothyroid – hypercalcaemia – drugs (opiate/auntie cholinergic's) – neuro disease – dehydration – sexual abuse ```
59
Management of constipation How long to continue treatment Treatment of the associated condition
For all [1] Diet: fibre cereal, whole wheat, fruit peel, veg, beans, nuts, juice, GOOD FLUID INTAKE [2] BEHAVIOURAL: SET TOILET TIMES, STAR CHANCE, REASSURANCE, ENCOURAGEMENT Mild constipation – polyethylene glycol 3350 + electrolytes (Movicol paediatric plan) LOW DOE REGIMEN +/- Stimulant e.g Senna if inadequate response Action impaction – polyethylene glycol 3350+ electrolytes (Movicol paediatric plan) ESCALATING DOE REGIMEN for 2/52 + Senna if inadequate response Continue treatment for a minimum of six months Consider treating anal fissures E.g. topical anaesthetic: Lidocaine
60
Differentiate IgE CMPA from non-IgE
``` IgE – Symptoms within two hours of ingestion (actually mins) Skin GI Resp ``` ``` Non-IgE mediated – sentence 48 hours to 1 week after ingestion GI Skin Resp ``` Diagnosis = elimination for 2-4 weeks, reintroduce 1 week Eliminate from diet (eHF or AAF if not good enough) or maternal diet. Continue for minimum 6 months until 9-12 months of age As long as new eczema – reintroduction at home using milk ladder If eczema – serum IgE of skin prick test – If negative reintroduction home with milk ladder – if positive refer to allergy clinic
61
Coeliac disease associations Genetic factors Management
``` Associations – type one diabetes – autoimmune viroid – down syndrome – family history of coeliac disease ``` Genetic factors – HLA DQ2/8 Management – dietician – lifelong gluten free diet plus calcium Plus vitamin di plus/minus iron
62
Dehydration: define ``` Not clinically detectable vs Clinical vs Shock ```
Not clinically detectable Less than 5% body weight lost ``` Clinical 5 to 10% body weight lost – increased HR increased our our – driving rain – reduced Urine Output – reduced skin turgor ``` ``` Shock Greater than 10% body weight lost – hypotensive – reduced conscious nurse – increased capillary refill time – week with a pulse – cold extremities – pale ```
63
Went to give IV fluids to a child IF not needed, what is given and how much for dehydration Advice for gastroenteritis recovery
Only if shook ORS and still dehydrated Persistent vomiting ORS 50ml/kg over 4h ``` Voice juice and carbonated drinks Hand washing Stay off school for 48 hours after last episode of diarrhoea Milk as normal when we hydrated Slowly introduce solid foods ```
64
GORD treatment Complications
[1] Don't overfeed: Max 150 mil per kilogram per day [2] Increased feed frequency (Two to 3 hourly) small feeds though [3] Feed thickener e.g. carobel If not better in two weeks – Omeprazole (PPI) – ranitidine (H to antagonist) ``` Prognosis is great Complications are rare – oesophagitis Aspiration pneumonia Faltering growth Apparent life-threatening events ```
65
GORD prevalence DORD risk factors
What a whopping 40% of Less than one-year-olds ``` Risk factors – premature – neuro disability – diaphragmatic hernia – oesophageal atresia ```
66
Pyloric stenosis features Risk factors
2 to 8 week old Non-bilious limiting, because projectile, characteristic bloods Weight loss Dehydration Rest factors – Male – 1st bordn – family history O/E: Olive in RUQ. Test feed: peristalsis left to right US DIAGNOSIS: Thickness of muscle > 3mm, length >15mm Management ONLY WHEN U&;ES STABLE Pre-op fluids to correct dehydration, NG trip and suck, maintenance fluids Op: Pyloromyotomy
67
Meckles diverticulum
Congenital diverticuli small intestine: remnant of the Vitello intestinal duct – contains pancreatic, ectopic, ileal Orgastic mucosa 2ft from ileocaecal valve, 2inches long, 2% of populatoon Asymptomatic PAINLESS Rectal bleeding Obstruction (volulus, hernia) Technechium scan US if suspect intusussception AXR to check obstruction Management - Asymptomatic found in surgery = excise - Symptomatic - Remove - wedge excision of small bowel excision and anastamosis
68
Malrotation Diagnosis Management
Congenital abnormality of the opposition --> complicated by volvulus Can be asymptomatic, obstruction with Compromise blood supply, bilious vomiting and abdominal pain Diagnosis - Upper GI CONTRAST STUDY - X-ray check for volvulus and obstruction ``` Management ABCDE LADD procedure 1) Detorsion of bowel 2) Recection of any necrotic bowel 3) Lysis of Ladd's bands 4) Caecum placed on left, small bowel on right 5) Appendicectomy ```
69
Define convulsive status epilepicus
Continuous seizure lasting more than 30 minutes or Intermittent clinical or EEG seizures lasting more than 30 minutes without full recovery of consciousness in between [0mins] Record time. ABC. High flow O2. Check GLUCOSE [5mins] Midazolam (0.5mg/kg) buccal or Lorazepam (0.1mg/kg) IV if access [15mins] Lorazepam (0.1mg/kg) IV PREP PHENYTOIN + SENIOR [25mins] Phenytoin 20mg/kg over 20mins IV or if regualar phenytoin Phenobarbitol 20mg/kh over 5mins IV INFORM ICU AND ANAESTHETIST [45mis] Induce anaesthesia using thiopental sodium IV
70
Paeds sepsis 6
``` [1] High flow oxygen [2] IV access - Blood glucose - Blood gas - Blood cultue - If poss U&Es, FBC, CRP [3] IV or IO antibiotics [4] Consider fluids - Aim UO >0.5ml/kg/hr - 10-20ml/kg isotonic fluid over 5-10mins - Repeat as necessary and monitor UO [5] Senior [6] Consider inotropes ```
71
Child adrenalise dose
1:1000 >12yo: 500micrograms (0.5ml) 6-12yo: 300micrograms (0.3ml) <6yo: 150micrograms (0.15ml) ``` Start with ABC Then IM adrenaline HIgh flow ox Then fluid challenge Chloramphenamine Hydrocortisone ```
72
Hepatosplenomegaly and the presence of bruising together with the symptoms of anaemia (soft systolic murmur and shortness of breath on exertion
DO NOT MISS ALL Anaemia: Pallor, therargy, SOB Leukopenia: Infections Thrombocytopenia: bruising and bleeding Other features: – bone pain (secondary to bone marrow infiltration) – splenomegaly – hepatomegaly – fever is present in up to 50% of new cases (representing infection or constitutional symptom) – testicular swelling
73
ALL poor prognosis
``` <2yo or >10yo WBC > 20 * 109/l at diagnosis T or B cell surface markers non-Caucasian male sex ```
74
Nappy rash causes and presentations
Irrirant dermatitis Most common - due to irritant effect of urinary ammonia and faeces. Creases are characteristically spared Candida dermatitis - Typically an erythematous rash which involve the flexures and has characteristic satellite lesions Seborrheic dermatitis Erythematous rash with flakes. May be coexistent scalp rash Atopic eczema - Other areas of the skin will also be affected
75
Nappy rash management
Disposable nappies are preferable to towel nappies Expose napkin area to air when possible Apply barrier cream (e.g. Zinc and castor oil) Mild steroid cream (e.g. 1% hydrocortisone) in severe cases Management of suspected candidal nappy rash is with a topical imidazole. Cease the use of a barrier cream until the candida has settled
76
Neonatal examination a systolic heart murmur is heard. An echocardiogram shows right atrial hypertrophy and the septal and posterior leaflet of the tricuspid valve attached to the right ventricle. What is the systolic murmur like
Ebstein's anomaly - Associated with lithium use PANSYSTOLIC
77
At what age to kids talk in short sentences (3-5words)
2.5-3yrs
78
SUFE presentation Diagnosis Management
10-15 years More common in obese children and boys Displacement of the femoral head epiphysis postero-inferiorly Bilateral slip in 20% of cases May present ACUTE following trauma or more commonly with CHRONIC persistent symptoms hip, groin, medial thigh or knee pain loss of internal rotation of the leg in flexion Diagnosis = x-ray AP and lateral (frog views) Management = internal fixation: typically a single cannulated screw placed in the center of the epiphysis
79
When is Men B vaccine given
2, 4, 12 months
80
Foreskin can't be retracted diagnosis
Phimosis Chill until after 2yo as will self resolve. Then refer
81
Newborn normal RR and pulse
HR: 110-160 Pulse: 30-60
82
Hand foot and mouth disease
Cause: COXACKIE A16 and enterovirus 71 = Hand, foot and mouth disease Clinical features mild systemic upset: sore throat, fever oral ulcers followed later by vesicles on the palms and soles of the feet Management symptomatic treatment only: general advice about hydration and analgesia reassurance no link to disease in cattle children do not need to be excluded from school*
83
APGAR SCORE INTERPRETATIOn
7-10 good 4-6 ok 0-3 v low Done at 1 min, 5 min and 10min
84
Features of Edward's
``` Trisomy 18 Small Jaw Overlapping fingers Rocker bottom feet Low set ears ```
85
What is kawasaki disease
``` 5 days or more of fever along with 4 of the following: [1] Dry cracked lips [2] Bilateral conjunctivitis [3] Peeling of skin on fingers and toes [4] Cervical lymphadenopathy [5] Red rash over trunk ``` Management High dose aspirin and IvIg
86
Most common complication of roseola infantum
FEBRILE SEIZURES ??? in 10-15% Also - Aseptic meningitis - hepatitis
87
Newborn with rash at 2-3days with white pinpoint papules at centre of erthematous base. Fluid contains eosinophils. They are on the trunk. Come and go
Erythema toxicum
88
Management of impetigo
[1st line] Topical Fusidic acid if localised [2nd line] topical retapamulin If extensive --> Flucloxacillin KEEP OFF SCHOOL UNTIL CRUSTED OVER or 48h after antibiotics
89
Bow legs Normal age Refer when
Present 1-2yrs old Typically resolves by the age of 4-5 years Increased intercondylar distance
90
Knock knees Nromal age
Present 3-4y Increased intermalleolar distance
91
Meconium ileus vs Hirschprung baby
Meconium ileus Usually delayed passage of meconium and abdominal distension The majority have CF NO fluid level as the meconium is viscid, PR contrast studies may dislodge meconium plugs and be therapeutic Infants who do not respond to PR contrast and NG N-acetyl cysteine will require surgery to remove the plugs Hirschsprung's Absence of ganglion cells from myenteric and submucosal plexuses Occurs in 1/5000 births Full-thickness rectal biopsy for diagnosis Delayed passage of meconium and abdominal distension Treatment is with rectal washouts initially, after that an anorectal pull through procedure
92
What age does a child play near other What age with others
Near: 2y With: 4yo
93
Where to check pulse in an infant
Brachial and femoral
94
Swelling in multiple joints and stiffness plus salmon pink rash
JIA
95
Perthes presentation
INSIDOUS onset of limp or hip or kww pain X-RAY both hops including frog views x-ray: early changes include widening of joint space, later changes include decreased femoral head size/flattening If persists and normal x-ray - MRI/Tch Management <6yo - Observe >6yo - screws and plates
96
life-threatening asthma attack are:
``` Cyanosis Poor respiratory effort Peak expiratory flow rate < 33% Silent chest Altered level of consciousness ```
97
absence of red-reflex, replaced by a white pupil (leukocoria) the most common presenting symptom strabismus visual problems
Retinoblastoma
98
What age does a child crawl
8 months
99
What age does a child sit What age to refer
7-8 months Refer at 12
100
Suspect septic arthritis over transient synovitis Management of septic arthritis
Kocher’s criteria states that certain factors are more likely to indicate septic arthritis over transient synovitis: temperature >38.5C, PAIN AT REST as well as movement refusal to bear weight on affected limb raised inflammatory markers (erythrocyte sedimentation rate >40 mm/hour and CRP > 20.0 mg/litre) a peripheral white cell count of > 12.0 x 109 (normal range 3.5 – 10.5 x 109 cells per cubic litre) Management of septic arthritis - Must do bloods (WCC), CRP, aspiration under US - Prolonged antibiotic course - Immobilize joint initially then mobilise
101
Nitrogen washout test
The nitrogen washout test (also known as the hyperoxia test) may be used to differentiate cardiac from non-cardiac causes. The infant is given 100% oxygen for ten minutes after which arterial blood gases are taken. A pO2 of less than 15 kPa indicates cyanotic congenital heart disease Causes of cyanotic congenital heart disease tetralogy of Fallot (TOF) transposition of the great arteries (TGA) tricuspid atresia
102
Infantile spasm attacks Presentation EEG Prognosis
Infantile spasms, or West syndrome, is a type of childhood epilepsy which typically presents in the first 4 to 8 months of life and is more common in male infants. They are often associated with a serious underlying condition and carry a poor prognosis Features characteristic 'salaam' attacks: flexion of the head, trunk and arms followed by extension of the arms this lasts only 1-2 seconds but may be repeated up to 50 times progressive mental handicap Investigation the EEG shows hypsarrhythmia in two-thirds of infants CT demonstrates diffuse or localised brain disease in 70% (e.g. tuberous sclerosis) Management poor prognosis vigabatrin is now considered first-line therapy ACTH is also used
103
HF in a child presentation
Heart failure typically presents in infants with symptoms of breathlessness worse on exertion (e.g. feeding), sweating, poor feeding and recurrent chest infections. On examination you should: examine the growth charts (?failure to thrive), examine for tachycardia, tachypnoea, murmurs and pre and post-ductal saturations. Heart failure may be due to duct dependant systemic circulations (<2 weeks old) e.g. coarctation of the aorta or left-to-right shunts (>2 weeks old) e.g. VSD as the pulmonary vasculature resistance begins to fall. In this case the baby has a large VSD causing decompensated heart failure. Cardiac lesions can be missed during the foetal anomaly scan and this baby would need a detailed foetal echocardiogram and discussion with the cardiac team on management strategies.
104
What does Guthrie sport screen for
``` congenital hypothyroidism cystic fibrosis sickle cell disease phenylketonuria medium chain acyl-CoA dehydrogenase deficiency (MCADD) maple syrup urine disease (MSUD) isovaleric acidaemia (IVA) glutaric aciduria type 1 (GA1) homocystinuria (pyridoxine unresponsive) (HCU) ```
105
Turner syndrome murmur
Systolic over the aortic valve - Biscuspid aortic valve
106
VSD murmur What at risk of
Pansystolic (low left sternal edge aka tricuspid) ``` Endocarditis PULMONARY HTN (not essential) ```
107
Neonate needs review from neonatal team
respiratory rate above 60 per minute the presence of grunting heart rate below 100 or above 160 beats/minute capillary refill time above 3 seconds temperature of 38°C or above, or 37.5°C on 2 occasions 30 minutes apart oxygen saturation below 95% presence of central cyanosis
108
What age can you use triptans in migrane from
12
109
Mild-moderate asthma attack treatment
Bronchodilator therapy - give a beta-2 agonist via a spacer (for a child < 3 years use a close-fitting mask). give 1 puff every 30-60 seconds up to a maximum of 10 puffs if symptoms are not controlled repeat beta-2 agonist and refer to hospital Steroid therapy should be given to all children with an asthma exacerbation treatment should be given for 3-5 days NB moderate = >92% sats >50 PEF ``` Severe in >5 pO2 < 92% PEF 33-50% best or predicted Can't complete sentences in one breath or too breathless to talk or feed Heart rate > 125/min Respiratory rate > 30/min Use of accessory neck muscles ```
110
When is hand preference normal
12 months
111
Correcting for developmen milestones until what age
2 THIS IS SNEAKY IN QUESTIONS
112
Head lice treatment
Combination of: malathion, wet combing, dimeticone, isopropyl myristate and cyclomethicone
113
Weight faltering definition Indications to investigate Causes Investigations Management
Drop down 2 centiles Indications for more investigations - Weight crossing 2 centiles - Below 0.4th centile - BMI <2nd centile Causes - INTAKE - feeding problems, type of feed, access to food, psycosocial deprivation, neglect/child abuse - Underlying pathology of low intake - cleft palate, CP, Chronic illness e.g. CKD, Chron's, CF, liver disease - INADEQUATE RETENTION - vom, GORD (severe) - MALABSORPTION - coeliac, CF, CMPA, NEC - FAILURE TO UTILISE NUTRIENTS - Down's, IUGR, congenital infection, metabolic disorders, diabetes - INCREASED REQUIREMENTS - Thyrotoxicosis, CF, malignancy, CKD, CHD ``` Investigations - only FBC and ferritin usually – FBC and WBC differential – U&Es (renal function, metabolic disturbance) – LFTs – TFT – CRP – ferritin – tissue transglutaminase antibodies – urine microscopy and culture and dip – to microscopy culture and dip – karyotyping girls Sweat test, chest x-ray ``` Management MDT in GP - health visitor, paediatric dietician, SALT, child psychologist, social services - If severe - admit? Takes 4-8 weeks
114
Short stature definition
below 2.5th centile ``` Causes – Constitutional – familial – chronic disease (CF, CHD, coeliac) – sickle-cell disease – thalassaemia – IBD – hypothyroid Dash down syndrome – malnutrition Less commonly - GH deficiency, CNS tumours, Turner, Noonan, Prader Wili ```
115
Where to refer developmental problems to Causes of global developmental delay
Local MDT services: Paediatricians and therapists - Screening tests - Standardized tests looking at specific areas of development ``` Causes [1] Antenatal - Chromosomal/DNA - Infections - Toxins/alcohol - Nurocutaneous [2] Perinatal - Extreme prematurity - HIE - Symptomatic hypoglycaemia - Hyperbilirubinaemia [3] Postnatal - Infection: Meningitis, encephalitis - Anoxia (seizures) - Head injury [4] Other - Chronic illness, physical abuse, emotional neglect ``` Tests - Chromosome analysis - FBC and ferritin - U&Es - TFTs - CK - Vision and hearing assessment
116
ADHD pathophysiology Managagement approach
Genetic component (0.7 heritability) - Prenatal exposure to nicotine - Pre and perinatal complications - LBW Refferral to community pediatrics/CAMHs - full assessment and diagnosis by psychiatrist. Must be in 2 or more setting - CONNERS rating scale (parent, teacher and child) Management - Behavioural + educational AKA MDT - 10 weeks watchful waiting possible - parent support groups then refer. If severe - immediate 2ndry care referral - PSychotherapy - Behavioral therapy - Parent education courses - CBT
117
CP management approach
Urgent assessment by child development centre --> local integrated MDT approach with local child development team: Specialist health visitor co-ordinated - SALT - OT - Physiotherapy - SENCO Support: SCOPE
118
What is a seizure
Paroxysmal abnormality of cognitive, autonomic, motor or sensory function due to transient brain dysfunction Epileptic seizure: when this is due ti underlyng electrical activity in the brain - usually excessive, hypersynchronous
119
Growing pains
``` 3-12yo Often wakes and relived by massaging - symmetrical lower limb pain (NOT limited to joints) - NOT present on walking - NOT limiting activities - NOT limping - Normal physical examination ```
120
What is osteomyelitis
Infection of metaphysis of long bone (often femur) - Can spread to joint causing septic arthritis PAINFUL, IMMOBILE, ACUTE febrile illness - Skin swollen, erythematous, warm and tender oabove Investigations - Blood cultures: +ve - WCC, WRP raised - US: Periosteal elevation - X-ray changes from 10 days: mottled rarefefaction, involucrum, lytic destruction, sequestra Management - Prompt antibiotics for 6 weeks (to prevent bone necrosis, chronic infection and limb deformity) - IV!!!!!! until CRP normal and symptoms reside - May need surgical drainage if response is poor
121
Osteochondritis dissecans
Localised tenderness over femoral condyles FOLLOWING AVASCULAR NECROSIS of medial femoral condyle - Slipping/locking/giving way Investigations - X-ray Management - Rest and quadriceps exercises - Sometime surgery required
122
Chondromalacia patellae
Softening of the articular cartilage of the patella - Pain when standing from sitting or going up stairs Management - Physio for quadrecep muscle straining - Painkillers
123
Limp red flags
``` <3 >9 Fever Pain waking at night - malignancy Redness, swelling or stiffness Weightloss anorexia, night sweats, fatigue Unexplained rash/bruising Worse in the morning - inflammatory joing disease Unable to weight bear Severe pain Suspect maltreatment ```
124
Reactive arthritis
Join swelling <6 weeks Oftern after an enteric infection: salmonella, shigella, campylobacter. Also viruses, STIs, Myocplas,a RF, post-strep Management - CRP mildly elevated only - X-ray normal NO TREATMENT NEEDED
125
CMPA management
Determine symptoms + relationship to milk. IF <2h - refer to allergy clinic If >2 hours, suggests not IgE mediated. Dietician supported trial of elimination from baby's diet/maternal diet WITH SUPPLEMENTS for 4 WEEKS (eHF for formula fed) - Clear improvement - confirm diagnosis with re-introduction (1 week) - Is symptoms return = confirms and get support of dietician - Cows milk protein free diet until 9-12 months - planned reintroduction (home if no atopic dermatitis or any hx of any immediate symptoms) - MILK LADDER
126
LP contraindications
``` Prolonged or focal seizure 
 Focal neurological signs 
 A widespread purpuric rash 
 A Glasgow Coma Scale score 13 
 Abnormal posture or movement e.g. decerebrate posture 
 An inappropriately low pulse, raised blood pressure and irregular breathing 
(suggesting impending brain herniation) 
 Thrombocytopenia or clotting disorder 
 Pupillary dilatation 
 Papilloedema 
 Hypertensio ```
127
Meningitis investigations once in hospital
``` FBC + CRP Glucose, gas, Coagulation screen, culture Blood PCR for N.meningitidis LP unless CI + cultue +/- PCR Rapid antigen tests on blood and urine Throat swabs for bacterial culture and viral PCR ``` Management - <3months: Cefotaxime - >3months: Ceftriaxone + dexamethasone CONSIDER ACICLOVIR IF SUSPECT ENCEPHALITIS Complications - Hearing impairment - Local vasculitis - Local cerebral infarction - Subdural effusion
128
pGALS
Any pain in back, muscles or joints? Trouble with stairs,?getting dressed? Gait - Walk normally - Tip toe - Heel walk Arms - Hand up to the ceiling - Hands behind your ears - Hands behind back - Hands straight out in front - Make a fist and turn (squeeze fists) - Touch fingers to thumb quick - Praying hands + FLIP - Bend thumb + fingers back Legs - on couch - Lift leg and bend - both legs - Flex and dorsiflex feet - Feel knee? - Spine - Look at back - trace down spine - Knees straight and touch your toes - Use kneck to look up - Chin down over chest - Look right, look left - Ear to shoulder on one side then the other - Open mouth and see if you can put three fingers in your mouth
129
Inhaler technique
1. Take off the cap and shake the inhaler 2. Put the inhaler into the end of your spacer 3. Breathe out gently as long as feels comfortable 4. Put the mouthpiece between your teeth and lips, making a seal so no medicine can escape 5. Press the canister to put one puff of your medicine into the spacer 6. Breathe in slowly and steadily (not hard and fast) through the mouthpiece 7. Keep the spacer in your mouth with your lips sealed around it and breathe in and out of the mouthpiece five times. Repeat the steps for each dose needed Clean spacer once a week by soaking in warm soapy water. Let air dry
130
JIA risk factors
``` Autoimmune disease Female Onset before 6 No infection or other cause Objective arthritis - >6 weeks ``` Characteristics - Worse in morning - Stiff - Most get better by adulthood ``` Management = MDT - specialist nurse, rheumatology, Exercise - swimming, cycling NSAIDs Steroids Methotrexate Immuno drugs ```
131
Turner syndrome On fetal US scan Complications
45, X. Usually maternal X chromosome. Many with Turner’s experience only short stature and ovarian failure. Picked up on fetal US  Cystic hygroma  Oedema of hands, neck and feet  Heart abnormalities eg. bicuspid aortic valve  Kidney abnormalities eg. horseshoe or pelvic kidney Complications 1. Heart defects (bicuspid aortic valve/coarctation of aorta/aortic root dilatation) 2. Kidney abnormalities eg. horseshoe kidney, recurrent UTIs 3. Lymphoedema 4. Hypothyroidism 5. HTN 6. Recurrent ear infections, hearing loss 7. Osteoporosis 8. Obesity and diabetes 9. ADHD in childhood Normal IQ in most but have difficulty with spacial reasoning
132
Investigations for Turner syndrome Management
```  Full examination inc. ENT  Urine dip  Developmental assessment  Gonadotrophin levels  Karyotype  Pelvic USS to rule out Mullerian agenesis ``` ``` Investigations for complications  TFTs, thyroid abs  HbA1c  Renal function tests: UEs, urine culture, imaging  ECG, echo  XR for bone age – delayed due to oestrogen def (GH contraindicated if epiphyses are fused)  Hearing tests ``` Management Explain nature of lifelong condition, and that Turner’s is NOT inherited. Main issues: growth, puberty, fertility, general health. MDT! Paediatric endocrinology, psychiatrist, gynaecologist, geneticist, nephrologist, ENT, cardiologist, specialist nurse  give GH if epiphyses not fused give oestrogen and progestogen (initially low dose oestrogen then add progestogen; later use COCP)  Fertility may be achieved with oocyte donation, and gamete or embryo transplantation. Screen for complications (see above) May need psych support also Educational support – SEN Support for family – can offer SW
133
Eczema management
Determine severity Mainstays of management - Triggers + conservative - Emollients - trial and error. Liberal - Topical corticoseroids (applied 20mins after emollients) - Immunomodulator and occlusive bandages by specialists only - Dietician mediated elimination of foods - Psychological support Steroids contine 48h after exacerbation Consider admission need Review anti-histamistamines every 3 months (can give short courses sedating for 2 weeks if bad) Review sterpods every 3-6 months
134
Fungal rash
KOH microscopy if unsure: Hyphae MUST FOR NAILS Woodlamp examination - UV light fluorescene of lesion Dermoscopy Fungal culture PCR Nail clippings Managmenet Tinea capitis - 4 weeks oral terbinafine +/- topical antifungals to reduce transmission - ketoconazole shampoo Tinea corporis - 7-8 days topical antifungal Tinea ungium - oral terbinafine OD 12 weeks (toenails), 6 weeks (finger nails)
135
Scabies investigation Management
Burroes pathognomic Ink burrow test Microscopy of skin scrapings from lesions = diagnosis Permethrin cream - leave on overnight. 2 doses, 1 week apart. WHOLE FAMILY - To cool skin that is clean - reapply to hands if wasshed - Mittens for infants Antihistamines for sleep Wash everything at 60 or higher after 1st treatment