Paeds Flashcards
Chickenpox
Fever initially
Itchy, rash starting on head/trunk before spreading. Initially macular then papular then vesicular
Systemic upset is usually mild
Measles
Prodrome: irritable, conjunctivitis, fever
Koplik spots: white spots (‘grain of salt’) on buccal mucosa
Rash: starts behind ears then to whole body, discrete maculopapular rash becoming blotchy & confluent
Mumps
Fever, malaise, muscular pain
Parotitis (‘earache’, ‘pain on eating’): unilateral initially then becomes bilateral in 70%
Rubella
Rash: pink maculopapular, initially on face before spreading to whole body, usually fades by the 3-5 day
Lymphadenopathy: suboccipital and postauricular
Hand, foot and mouth
Caused by the coxsackie A16 virus
Mild systemic upset: sore throat, fever
Vesicles in the mouth and on the palms and soles of the feet
Erythema infectiosum
Also known as fifth disease or ‘slapped-cheek syndrome’
Caused by parvovirus B19
Lethargy, fever, headache
‘Slapped-cheek’ rash spreading to proximal arms and extensor surfaces
Scarlet fever
Reaction to erythrogenic toxins produced by Group A haemolytic streptococci
Fever, malaise, tonsillitis
‘Strawberry’ tongue
Rash - fine punctate erythema sparing face
Patau syndrome - trisomy 13
Microcephalic, small eyes
Cleft lip/palate
Polydactyly
Scalp lesions
Fragile X
Learning difficulties Macrocephaly Long face Large ears Macro-orchidism
Vaccination schedule:
2 months
5in1 - DTaP/IPV(polio)/Hib
PCV (pneumococcal)
Rotavirus
Vaccination schedule:
3 months
5in1 - DTaP/IPV/Hib 2nd dose
Men C
Rotavirus 2nd dose
Vaccination schedule:
4 months
5in1 - DTaP/IPV/Hib 3rd dose
PCV (pneumococcal) 2nd dose
Vaccination schedule:
12-13 months
Hib/Men C booster
MMR
PCV (pneumococcal) 3rd dose
Vaccination schedule:
2, 3, 4 yrs plus years 1 + 2 school
Flu vaccine
Vaccination schedule:
From 3 yrs 4 months up to year 1 school
MMR 2nd dose
4in1 pre-school booster - DTaP/IPV
Vaccination schedule:
12-13 years girls only
HPV
Vaccination schedule:
13-18 years
3in1 booster - TD/IPV
Vaccination schedule:
13-15 years
Men C booster
Pierre-Robin syndrome
Micrognathia
Posterior displacement of the tongue (may result in upper airway obstruction)
Cleft palate
Knee problems - children and young adults
Chondromalacia patellae
Softening of the cartilage of the patella
Common in teenage girls
Characteristically anterior knee pain on walking up and down stairs and rising from prolonged sitting
Usually responds to physiotherapy
Knee problems - children and young adults
Osgood-Schlatter disease
(tibial apophysitis)
Seen in sporty teenagers
Pain, tenderness and swelling over the tibial tubercle
Knee problems - children and young adults
Osteochondritis dissecans
Pain after exercise
Intermittent swelling and locking
Knee problems - children and young adults
Patellar subluxation
Medial knee pain due to lateral subluxation of the patella
Knee may give way
Knee problems - children and young adults
Patellar tendonitis
More common in athletic teenage boys
Chronic anterior knee pain that worsens after running
Tender below the patella on examination
Klinefelter’s syndrome - Primary hypogonadism
Klinefelter’s syndrome is associated with karyotype 47, XXY
Features often taller than average lack of secondary sexual characteristics small, firm testes infertile gynaecomastia - increased incidence of breast cancer elevated gonadotrophin levels
Diagnosis is by chromosomal analysis
Kallman’s syndrome - Hypogonadotrophic hypogonadism
Kallman’s syndrome is a recognised cause of delayed puberty secondary to hypogonadotrophic hypogonadism. It is usually inherited as an X-linked recessive trait. Kallman’s syndrome is thought to be caused by failure of GnRH-secreting neurons to migrate to the hypothalamus.
The clue given in many questions is lack of smell (anosmia) in a boy with delayed puberty
Features
‘delayed puberty’
hypogonadism, cryptorchidism
anosmia
sex hormone levels are low
LH, FSH levels are inappropriately low/normal
patients are typically of normal or above average height
Cleft lip/palate and visual/hearing defects are also seen in some patients
Androgen insensitivity syndrome
Androgen insensitivity syndrome is an X-linked recessive condition due to end-organ resistance to testosterone causing genotypically male children (46XY) to have a female phenotype. Complete androgen insensitivity syndrome is the new term for testicular feminisation syndrome
Features
‘primary amennorhoea’
undescended testes causing groin swellings
breast development may occur as a result of conversion of testosterone to oestradiol
Diagnosis
buccal smear or chromosomal analysis to reveal 46XY genotype
Management
counselling - raise child as female
bilateral orchidectomy (increased risk of testicular cancer due to undescended testes)
oestrogen therapy
Edwards syndrome - trisomy 18
Micrognathia
Low-set ears
Rocker bottom feet
Overlapping of fingers
Noonan syndrome
Webbed neck
Pectus excavatum
Short stature
Pulmonary stenosis
Prader-Willi syndrome
Hypotonia
Hypogonadism
Obesity
William’s syndrome
Short stature Learning difficulties Friendly, extrovert personality Transient neonatal hypercalcaemia Supravalvular aortic stenosis
Hip problems in children
DDH
Often picked up on newborn examination
Barlow’s test, Ortolani’s test are positive
Unequal skin folds/leg length
Hip problems in children
Transient synovitis
Typical age group = 2-10 years
Acute hip pain associated with viral infection
Commonest cause of hip pain in children
Hip problems in children
Perthes disease
Perthes disease is a degenerative condition affecting the hip joints of children, typically between the ages of 4-8 years. It is due to avascular necrosis of the femoral head
Perthes disease is 5 times more common in boys. Around 10% of cases are bilateral
Features
hip pain: develops progressively over a few weeks
limp
stiffness and reduced range of hip movement
x-ray: early changes include widening of joint space, later changes include decreased femoral head size/flattening
Hip problems in children
SUFE
Typical age group = 10-15 years
More common in obese children and boys
Displacement of the femoral head epiphysis postero-inferiorly
Bilateral slip in 20% of cases
May present acutely following trauma or more commonly with chronic, persistent symptoms
Features
knee or distal thigh pain is common
loss of internal rotation of the leg in flexion
Hip problems in children
JIA
Preferred to the older term juvenile chronic arthritis, describes arthritis occurring in someone who is less than 16 years old that lasts for more than three months. Pauciarticular JIA refers to cases where 4 or less joints are affected. It accounts for around 60% of cases of JIA
Features of pauciarticular JIA
joint pain and swelling: usually medium sized joints e.g. knees, ankles, elbows
limp
ANA may be positive in JIA - associated with anterior uveitis
Hip problems in children
Septic arthritis
Acute hip pain associated with systemic upset e.g. pyrexia. Inability/severe limitation of affected joint
6-year-old girl is investigated for precocious puberty. On examination she is noted to have cafe-au-lait spots predominately on one side of her body and a skull deformity
McCune-Albright syndrome
Little or no head lag on being pulled to sit
Lying on abdomen, good head control
Held sitting, lumbar curve
3 months
Lying on abdomen, arms extended Lying on back, lifts and grasps feet Pulls self to sitting Held sitting, back straight Rolls front to back
6 months
Sits without support (refer at 12 months)
7-8 months