Paeds 1 Flashcards
What Abx do you give for meningitis? before admission on admission (neonates, 1-3m, >3m)
Before admission: benzylpenicillin Admission: Neonate - benzylpenicillin/ amoxicillin + gentamicin 1-3m - cefotaxime + amoxicillin >3m - ceftriaxone
What Abx do you give for sepsis?
IV Ceftriaxone
What Abx do you give for pneumonia?
Typical & Atypical
Typical: Oral amoxicillin
Atypical: erythromycin/clarithromycin
What Abx do you give for UTI? <3m >3m & pyelonephritis Lower UTI Prophylaxis
<3m: IV ceftriaxone/cefotaxime + amoxicillin
> 3m with pyelonephritis:
If well - oral cephalexin/co-amoxiclav
If severe - IV co-amox/cefuroxime
Lower UTI: Trimethoprim Nitrofurantoin Cephalexin Amoxicillin
Prophylaxis:
Low dose trimethoprim/nitrofurantoin (2nd line - amox/cefalxein)
What Abx would you give for otitis media?
Amoxicillin/ erythromycin
What Abx would you give for tonsillitis?
Phenoxymethylpenicillin/ clarythromycin
What Abx would you give in CF for:
prophylaxis
pseudomonas infection
Prophylaxis: flucloxacillin
Pseudomonas: inhaled colistimethate sodium/ Tobramycin
What Abx would you give for whooping cough?
Erythromycin
What Abx would you give for TB?
Rifampicin
Isoniazid
Pyrazinamide
Ethambutol
What Abx would you give for epiglottitis?
IV cefuroxime
Constipation
1st line
2nd line
3rd line
1st - Macrogol
2nd - stimulant (Senna)
3rd - lactulose (osmotic)/ docusate sodium
Eczema:
Emollients - 1 thin, 3 thick (ointment)
Steroids - mild, moderate, potent, v potent
SEs of steroids
Emollients (use after washing & 2/3 times in day):
Thin - E45
Thick (ointment) - Diprobase, Hydromol, 50:50 (50% liquid paraffin)
Steroids (apply 1-2/day): Mild - hydrocortisone Moderate - Eumovate Potent - betnovate V potent - dermovate
SEs: thinning - more prone to flares, bruising, tearing
Croup Oral steroids (2) Nebulised Steroids (1)
Oral:
Dexamethasone/ Prednisolone
Nebulised:
Budesonide
Name, onset & duration of: Rapid acting insulin Short acting insulin Intermediate insulin Long acting
Humalog - 10min --> 30-90mins Actrapid, humulin - 30-60mins --> 2-5hr Isophane - 1-2hr --> 4-12 hr Levemic - 1-2hr --> 20hr
What is in a mixed insulin preparation?
Shorting acting & long acting
What is a basal bolus regime of insulin?
Long acting in evening
Shorting acting 3x/day before meals
Hypoglycaemia management if:
conscious (g of glucose by 10kg, 30kg, 50kg child)
unconscious (3)
Conscious: sugary snap/ hyostop gel - 10kg child = 5g glucose - 30kg = 10g glucose - 50kg = 15g glucose
Unconscious: - Hypostop gel on buccal mucosa - IV 10% dextrose 2mls/kg, followed by glucose infusion - SEVERE - glucagon IM <8yrs = 500mcg, >8yrs = 1mg
Antiepileptics for:
Absence seizure
Sodium valproate
Ethosuximide
Antiepileptics for: Myoclonic seizure (1st & 2nd lines)
1st - Sodium Valproate
2nd - Lamotrigine, levetiracetam, topiramate
Antiepileptics for:
Tonic clonic seizure (1st & 2nd line)
1st - sodium valproate
2nd - lamotrigine, carbamazepine
Antiepileptics for: Atonic seizure (1st & 2nd line)
1st - sodium valproate
2nd - lamotrigine
Antiepileptics for: focal seizures (1st & 2nd line)
1st - carbamazepine/lamotrigine
2nd - sodium valproate/levetiracetam
2 Medications used for west syndrome seizure
Prednisolone
Vigabatrin
Desmopressin
- mechanism of action
- indications
- contraindications
- SEs
1) anti-diuretic hormone = increase water reabsorption & reduce urine output Increase levels of plasma VIII 2) primary nocturnal enuresis, diabetes insipidus, haemophilia, von Willebrand's disease 3) Diuretics Cardiac insufficiency SIADH Hx of hyponatraemia 4) Hyponatraemia
What steroid do you give for nephrotic syndrome + how much?
Prednisolone
60mg/m^2 OD 4-6 weeks until proteinuria ceases
Reduce to 40mg/m^2 OD alternate days 4-6weeks
Reduce dose gradually
Rickets: Treatment Prevention - mechanism of action of each - contraindications (same for both) - SEs (same for both)
Treatment: ergocalciferol
- absorbs Ca & PO4 from intestine, reabsorbs them from kidney, growth of Ca & PO4 in bone
Prevention: cholicalciferol (Vit D3)
- metabolised in liver –> calcidol –> metabolised in kidney –> calcitriol –> maintain Ca & PO4 homeostasis (absorption of Ca & PO4 in small intestine –> bone mineralisation)
- CI: hypercalceamia
- SEs: hypercalcaemia, hypercaliurea, abdo pain, nausea