Paediatrics Flashcards
1
Q
Absorption
A
decreased in neonates and infants
2
Q
pH stomach
A
high (7) adult value at 2 yrs
3
Q
Penicillin
A
increased oral F in neonates
4
Q
Phenytoin
A
decreased absorption neonates
5
Q
Gastric Emptying
A
increased neonates increased intestinal transit time
6
Q
Bile acid production
A
decreased neonates decrease F of certain drugs
7
Q
Vd for hydrophilic
A
increased neonates
8
Q
Albumin
A
decreased neonates
decrease fraction unbound
9
Q
Enzyme capacity
A
decreased
decreased hepatic clearance and blood flow
10
Q
GFR
Tubular reabsorption
A
low rapidly increasing
adult at 2 yrs
11
Q
% adult dose calc
A
= SA of child/1.73 x 100
