Paediatrics Flashcards

1
Q

Brain injury is a common feature contributing to the course and outcome of meconium aspiration
True or False?

A

True

Loss of sphincter control in the uterus is unlikely as it is a poorly developed reflex, therefore uncommon in neonates and is often associated with listeria infection. For term babies this reflex is well developed and is more common.
• Term babies will require hypoxic and ischaemic insults in order to relax sphincter
• A further strong inspiratory reflex is required to inspirate
• Inspiration of meconium is a sign of severe hypoxic ischaemic brain injury

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2
Q

Neonatal Respiratory Distress Syndrome is expected to improve following the initial 24 hours after birth
True or False?

A

False

NRDS affects premature babies due to surfactant deficiency (Hyaline membrane disease). It begins at 6 hours after birth and is worst between 24-48 hours before improving
• Treatment include giving steroids during pregnancy and tocolytics to prevent early delivery
• Once delivered management is with surfactant and CPAP

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3
Q

In the absence of fever, hypothyroidism is the most common cause of sleepiness in a newborn baby
True or False?

A

False

The cause of sleepiness may be physiological or pathological. It is important to differentiate between the two in order to
• Physiological – due to the stressful nature of birth/sleep cycle is much faster in neonates
• Pharmacological – maternal intake of medication during birth/whilst breast feeding
• Pathological – non specific sign of illness e.g. hyponatraemia/hypoglycaemia/infection/hypothyroidism

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4
Q

Intrapartum antibiotic prophylaxis protects babies against Group B Streptococcal sepsis throughout the neonatal period
True or False?

A

False

It prevents Group B Streptococcal sepsis at the beginning but not the entire duration of the neonatal period.
• E.Coli/Group B streptococcal (and gram negatives) are present in the digestive tract and so are the most common causative first organisms
• Can present in the first 48hrs after birth or delayed within the first few months, usually presenting as meningitis
• It is a medical emergency due to aggressive nature of infection
• Treatment is two doses @12hours of penicillin given Intrapartum that protects for the first 48hours after birth but not for duration of neonatal period

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5
Q

Neck rigidity and bulging fontanelle are useful features for the diagnosis of bacterial meningitis in newborn babies
True or False?

A

False

Young infants are very bad at amounting an immune response.
• It will take a long time for neck rigidity to manifest due to irritation of meninges
• Bulging fontanelle will take a while as there is a lot of room for expansion
• Both present too late and are not a useful measure

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6
Q

Cardiac murmurs detected on routine neonatal check 72 hours after birth, require more prompt assessment than those during a screening visit at two years of age
True or False?

A

True

Changes from foetal to neonatal circulation occur following birth
• This is an important time as duct dependency will manifest itself. Has three distinct casues:
(1) Severe tetraphalogy or conditions with impaired right ventricular circulation leading to a LR shunt
(2) Severe left ventricular circulation impairment that leads to a RL shunt
(3) No mixing between the two circulations (transposition of the great vessels)

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7
Q

APGAR score includes RR.

True or False?

A

False

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8
Q

APGAR score includes capillary return

True or False?

A

False

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9
Q

APGAR score at 5 min has an important role in determining resuscitation interventions.
True or False?

A

False

Used at 5/10/15/20 minutes for prognostic information to see how neurodevelopment will occur

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10
Q

APGAR scores are important determinants of the need for intensive care of extremely premature babies
True or False?

A

False

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11
Q

APGAR scores can be artificially lowered by intra-partum use of analgesia and sedation
True or False?

A

True

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12
Q

In resuscitation of babies at birth, adrenaline should be given if the hear rate is below 40 per minute
True or False?

A

False
In adults primary event leading to cardiac arrest is cardiovascular. In children it is most commonly due to respiratory events with cardiac arrest occurring as a secondary complication.
• Management: initial O2 and mucosal aspiration, if no response, cardiac assistance (adrenaline)

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13
Q

Intra-ventricular haemorrhage is a recognised complication of forceps delivery
True or False?

A

False
Intra-ventricular haemorrhage is specific to premature births. Occurs due to large rapid changes in blood pressure that causes damage to poorly developed choroid plexus

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14
Q

Low body temperature is a sign of systemic infection in young infants
True or False?

A

True

This can occur due to the larger surface area and thinner skin in infants

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15
Q

Peri-umbilical redness precedes cord separation

True or False?

A

False
Umbilical stump will fall off within two weeks due to necrosis
• Redness SHOULD NOT extend to the area around the umbilicus
• If it is red it require IV antibiotics and admission to hospital as it is an easy site of peritoneal infection

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16
Q

Seizures in premature babies can manifest only in colour change
True or False?

A

True
Due to lack or presence of myelin so are unable to have visible seizures just localised ones
• It is believed that you are born with the same amount of nerves as when you die. However, it is due to myelination that we develop progression of higher cognition and motor development

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17
Q

Breast fed babies are at a higher risk of haemorrhagic disease of the newborn
True or False?

A

True
Breast feeing can casue generalised jaundice
• Haemorrhagic disease in the newborn is caused by a lack of vitamin K
• Formulae milk has Vitamin K addition, whereas breast does not

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18
Q

Asthma is a common cause of recurrent wheezing in infancy

True or False?

A

DK
There is no conclusive evidence to point to this
• Wheeze is a dry, continuous, polyphonic noise
• Asthma is caused by reversible airways obstruction due to hyper-responsive airways caused by IgE mediated inflammation (usually) that is brought on by either allergic/infective or autoimmune parameters

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19
Q

Apnoea is common in young babies with bronchiolitis

True or False?

A

True

Preterm infants or full term infants in the first 4 weeks of life can present with this

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20
Q

Babies with bronchiolitis showing respiratory distress but no wheeze can be managed at home
True or False?

A

False

This requires muscular effort and babies will eventually tire, leading to lack of inspiration and eventual resp failure

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21
Q

Dehydration is a frequent complication of bronchiolitis

True or False?

A

True

This can occur due to a lack of appetite

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22
Q

Hospitalised infants with bronchiolitis are at risk of fluid overload
True or False?

A

True

Most commonly due to SIADH where respiratory manifestation is most common

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23
Q

In a baby with vomiting and significant METABOLIC ACIDOSIS
Pyloric stenosis is a common underlying cause
True or False?

A

False
Due to the production of bicarbonate caused by excessive vomiting metabolic alkalosis would occur. So this is false.
• Additionally repeatedly vomiting would relax your pyloric sphincter, lessening your stenosis and would lead to a less severe form of alkalosis

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24
Q

In a baby with vomiting and significant METABOLIC ACIDOSIS
Hyperkalaemia maybe present despite potassium depletion
True or False?

A

True
In this situation a shift from intracellular to extracellular concentration can occur
• This gives a false value and an impression of normal values
• Management: give fluids then K+ once kidneys are well perfused (unless in situations of pyloric stenosis or diabetes)

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25
Q

In a baby with vomiting and significant METABOLIC ACIDOSIS
Tetany can occur despite normal calcium levels
True or False?

A

False
This is caused by hypocalcaemia
• Calcium is in the blood (50% bound/50% unbound)
• Unbound is “active calcium”
• Acidosis does not change total calcium levels but it does cause a shift towards unbound “active” calcium leading to hypercalcaemia
• Alkalosis causes a shift towards bound “non-active” calcium leading to hypocalcaemia and subsequent tetany
o Hyperventilation/renal failure

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26
Q

In a baby with vomiting and significant METABOLIC ACIDOSIS
High lactate may suggest poor circulation
True or False?

A

True

Poor circulation/sepsis or infection leads to increased lactate caused by poor perfusion

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27
Q

In a baby with vomiting and significant METABOLIC ACIDOSIS
High ketones may be the explanation
True or False?

A

True

Ketones are acidotic and can be caused by starvation

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28
Q

In a baby with vomiting and significant METABOLIC ACIDOSIS
In the presence of hypoglycaemia, ketonuria would point to hyperinsulism
True or False?

A

Uncertain

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29
Q

In a baby with vomiting and significant METABOLIC ACIDOSIS
Genetic metabolic disorders need to be considered
True or False?

A

False

If no other diagnosis is possible

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30
Q

Clindamycin IV +/- Immunoglobulin, 3rd Generation Cephalosporin IV, 3rd Generation Cephalosporin plus Vancomycin IV, IV co-amoxiclave, 3rd Generation Cephalosporin plus Flucloxacillin IV, 3rd Generation Cephalosporin plus Acyclovir plus a Macrolide IV, Trimethoprim orally, None, Oral Penicillin V

What is the most suitable antimicrobial treatment for: Scarlet Fever

A

Oral Penicillin V

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31
Q

Generation Cephalosporin IV, 3rd Generation Cephalosporin plus Vancomycin IV, IV co-amoxiclave, 3rd Generation Cephalosporin plus Flucloxacillin IV, 3rd Generation Cephalosporin plus Acyclovir plus a Macrolide IV, Trimethoprim orally, None, Oral Penicillin V

What is the most suitable antimicrobial treatment for:
Reseola Infantum in a 2 year old

A

None

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32
Q

Generation Cephalosporin IV, 3rd Generation Cephalosporin plus Vancomycin IV, IV co-amoxiclave, 3rd Generation Cephalosporin plus Flucloxacillin IV, 3rd Generation Cephalosporin plus Acyclovir plus a Macrolide IV, Trimethoprim orally, None, Oral Penicillin V

What is the most suitable antimicrobial treatment for:
Fever with no focus in 4 year old

A

None

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33
Q

Generation Cephalosporin IV, 3rd Generation Cephalosporin plus Vancomycin IV, IV co-amoxiclave, 3rd Generation Cephalosporin plus Flucloxacillin IV, 3rd Generation Cephalosporin plus Acyclovir plus a Macrolide IV, Trimethoprim orally, None, Oral Penicillin V

What is the most suitable antimicrobial treatment for:
Severe peri-orbital celulitis

A

3rd Generation Cephalosporin plus Flucloxacillin IV (caused by Staph aureus, Pneumococcus, Staph Epidermis)

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34
Q

Generation Cephalosporin IV, 3rd Generation Cephalosporin plus Vancomycin IV, IV co-amoxiclave, 3rd Generation Cephalosporin plus Flucloxacillin IV, 3rd Generation Cephalosporin plus Acyclovir plus a Macrolide IV, Trimethoprim orally, None, Oral Penicillin V

What is the most suitable antimicrobial treatment for:
UTI in a 4 year old

A

Trimethoprim only

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35
Q

Generation Cephalosporin IV, 3rd Generation Cephalosporin plus Vancomycin IV, IV co-amoxiclave, 3rd Generation Cephalosporin plus Flucloxacillin IV, 3rd Generation Cephalosporin plus Acyclovir plus a Macrolide IV, Trimethoprim orally, None, Oral Penicillin V

What is the most suitable antimicrobial treatment for:
Septic knee arthritis in non-immunised 2 year old

A

3rd Generation Cephalosporin plus Flucloxacillin IV (if immunised can given only Flucloxacillin) you are worried about Haemophilus Influenza B in non immunised child

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36
Q

Generation Cephalosporin IV, 3rd Generation Cephalosporin plus Vancomycin IV, IV co-amoxiclave, 3rd Generation Cephalosporin plus Flucloxacillin IV, 3rd Generation Cephalosporin plus Acyclovir plus a Macrolide IV, Trimethoprim orally, None, Oral Penicillin V

What is the most suitable antimicrobial treatment for:
Florid meningitis in a 3 year old with encephalopathic picture preceded by respiratory problems

A

3rd Generation Cephalosporin plus Vancomycin IV (for atypical infections such as Aspergillus)

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37
Q

Generation Cephalosporin IV, 3rd Generation Cephalosporin plus Vancomycin IV, IV co-amoxiclave, 3rd Generation Cephalosporin plus Flucloxacillin IV, 3rd Generation Cephalosporin plus Acyclovir plus a Macrolide IV, Trimethoprim orally, None, Oral Penicillin V

What is the most suitable antimicrobial treatment for:
Semi-comatosed 8 year old with encephalopathic picture preceded by respiratory symptoms

A

3rd Generation Cephalosporin plus Acyclovir plus a Macrolide IV (this is triple therapy for a picture of Encephalitis/Meningitis. Herpes is particularly severe and macrolide is used to treat Mycoplasma

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38
Q

Generation Cephalosporin IV, 3rd Generation Cephalosporin plus Vancomycin IV, IV co-amoxiclave, 3rd Generation Cephalosporin plus Flucloxacillin IV, 3rd Generation Cephalosporin plus Acyclovir plus a Macrolide IV, Trimethoprim orally, None, Oral Penicillin V

What is the most suitable antimicrobial treatment for:
A child with an infected skin lesion who developed generalised erythema, diarrhoea and postural hypotension

A

Clindamycin IV +/- immunoglobulin (This is toxic shock syndrome. Clindamycin weakens the bacteria and reduces toxin production whilst immunoglobulins neutralise the pre-produced toxins in order to reduce toxic effect)

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39
Q

The following are indications for admission to hospital for a young infant with bronchiolitis:
RR of 45 per minute
True or False?

A

False
Respiratory rates and age groups:
• Very preterm:

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40
Q

The following are indications for admission to hospital for a young infant with bronchiolitis:
Reduced feeding intake
True or False?

A

True

Reduced feeding intake is worrying as it can lead to acute starvation and dehydration

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41
Q

The following are indications for admission to hospital for a young infant with bronchiolitis:
HR of 80 per minute
True or False?

A

False

Hypoxia in infants results in a bradycardic effect

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42
Q

The following are indications for admission to hospital for a young infant with bronchiolitis:
Concerns regarding social history
True or False?

A

True

Must be confident that the parents are able to provide for the child, regardless of situation

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43
Q

The following are indications for admission to hospital for a young infant with bronchiolitis:
Sleepiness
True or False?

A

True

Sleepiness combined with respiratory pathology is a worrying situation

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44
Q

In a 7 year old child during an acute asthmatic attack, the following signs are reassuring:
Haemoglobin oxygen saturation monitor reading of 92%
True or false?

A

False
A normal saturation does not mean an absence of pathology. You can have serious progression (down to 7PaO2) before any changes in saturation are noticed
• Even at lowest saturation i.e. venous blood haemoglobin uptake is roughly at 75%
• Remember the sigmoid curve

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45
Q

In a 7 year old child during an acute asthmatic attack, the following signs are reassuring:
Absence of wheeze
True or false?

A

False

“silent chest” is a very serious sign of severe asthma

46
Q

In a 7 year old child during an acute asthmatic attack, the following signs are reassuring:
Improvement following salbutamol via spacer lasting for 60 minutes
True or false?

A

False

You would ideally like to see improvement that lasts for 3-4 hours before you are willing to discharge the child

47
Q

In a 7 year old child during an acute asthmatic attack, the following signs are reassuring:
Wheeze only on one side
True or false?

A

False

Wheeze on one side could indicate pathology: pulmonary collapse, pneumothorax, foreign body inhalation

48
Q

In a 7 year old child during an acute asthmatic attack, the following signs are reassuring:
pCO2 of 6.9 kPa on arterial blood gasses
True or false?

A

False
With moderate asthma you see polypic, hypocapnoea with a moderate or low PCO2. With severe asthma you see a high or a rising CO2

49
Q

Urinary tract infections (UTIs) in infants and young children are unlikely in the absence of urinary symptoms
True or False?

A

Fase

There can be a fever with no obvious source

50
Q

Urinary tract infections (UTIs) in infants and young children, group A strep is a likely cause
True or False?

A

False

E.Coli is the most common causative agent

51
Q

Urinary tract infections (UTIs) in neonates can manifest in prolonged jaundice
True or False?

A

True

UTIs can be one of the causes of non specific jaundice in neonates

52
Q

Urinary tract infections (UTIs) in infants and young children are unlikely in children under 3 years of age if the urine dipstick is completely negative
True or False?

A

False
Urine dipsticks are very sensitive
• Babies are poor at mounting an inflammatory response so very few WCs can be found leading to a false negative
• Nitrites in the urine are also time dependent. Usually urine does not stay long enough in the bladder as the first thing that happens in infants is automatic voiding to combat inflammation or infection. Hence giving a false negative

53
Q

Urinary tract infections (UTIs) in infants and young children have renal cysts as a common associated abnormality
True or False?

A

False
Structural abnormalities are the most common PUJ stenosis/reflux nephropathy
• Children present usually due to:
(1) UTIs present with generalised symptoms
(2) Can scar kidneys  leading to completely dysfunctional kidneys
(3) 50% have an underlying abnormality
• Risk factors for UTIs include: dehydration, constipation, nappy hygiene
• Grade I-III reflux is treated conservatively
• Grade IV reflux is treated surgically

54
Q

Urinary tract infections (UTIs) in infants and young children can manifest in drowsiness
True or False?

A

True

Non specific drowsiness is due to the absorption of ammonia that has crossed the blood brain barrier

55
Q

Loose motions can be a sign of constipation

True or False?

A

True

Overflow diarrhoea

56
Q

Constipation is a risk factor for UTI in children

True or False?

A

True

Not clear as to why. One theory is the translocation of bacteria across intact walls

57
Q

Bruising in immobile children is a strong indicator of physical abuse
True or False?

A

True
Any bruising in immobile children that remains medically unexplained is a cause of concern. As a clinician you are allowed to have an indication but not make an accusation

58
Q

Bone fractures in infants are frequently a sign of metabolic bone disease
True or False?

A

False

Less than 1% are due to metabolic disorders

59
Q

In left handed children, left hand use preference can be noticed from 4 months of age
True or False?

A

False
Use preference can be noticed from 3 years onwards
• The presence of speech and language centre on either side of the brain only occurs at 2-3 years of age
• This is when hand dominance occurs as well
• If this occurs any earlier it is a pathological sign, showing hemiplegia

60
Q

A 2 month old baby was brought to the GP with 24 hour history of refusal of feeds, vomiting, 2 diarrhoeal stools and sleepiness alternating with irritability. The baby has a slightly changed cry and his young mum is quite worried saying that her baby “looks different”. Is the following statement true or false regarding this case:

A temperature of 39oC that responds promptly to Paracetamol and/or Ibuprofen strongly suggests a viral aetiology

A

False

You cannot differentiate between bacterial or viral infection with Paracetamol response

61
Q

A 2 month old baby was brought to the GP with 24 hour history of refusal of feeds, vomiting, 2 diarrhoeal stools and sleepiness alternating with irritability. The baby has a slightly changed cry and his young mum is quite worried saying that her baby “looks different”. Is the following statement true or false regarding this case:

Serious bacterial infection is unlikely if there is no fever

A

False

Infants are not able to mount a proper immune response

62
Q

A 2 month old baby was brought to the GP with 24 hour history of refusal of feeds, vomiting, 2 diarrhoeal stools and sleepiness alternating with irritability. The baby has a slightly changed cry and his young mum is quite worried saying that her baby “looks different”. Is the following statement true or false regarding this case:

If the vomiting and diarrhoea stop and there are no signs of dehydration, admission to hospital is not necessary

A

False
Babies with less than 3 months are at high risk and all indicators point to CNS involvement. Unsafe to send home

63
Q

A 2 month old baby was brought to the GP with 24 hour history of refusal of feeds, vomiting, 2 diarrhoeal stools and sleepiness alternating with irritability. The baby has a slightly changed cry and his young mum is quite worried saying that her baby “looks different”. Is the following statement true or false regarding this case:

In the absence of any neck rigidity, meningitis is unlikely

A

False

64
Q

A 2 month old baby was brought to the GP with 24 hour history of refusal of feeds, vomiting, 2 diarrhoeal stools and sleepiness alternating with irritability. The baby has a slightly changed cry and his young mum is quite worried saying that her baby “looks different”. Is the following statement true or false regarding this case:

Oral rehydration should be attempted for 8 hours before considering admission to hospital for IV infusion of fluids

A

False

8 hours is too long

65
Q

Enteroviral infection can present as fever with no obvious cause in an otherwise reasonably well toddler
True or False?

A

True

66
Q

Ottitis Media can present as fever with no obvious cause in an otherwise reasonably well toddler
True or False?

A

True

67
Q

UTI can present as fever with no obvious cause in an otherwise reasonably well toddler
True or False?

A

True

68
Q

Pneumonia can present as fever with no obvious cause in an otherwise reasonably well toddler
True or False?

A

True

69
Q

Meningitis can present as fever with no obvious cause in an otherwise reasonably well toddler
True or False?

A

True

70
Q

Bacteraemia can present as fever with no obvious cause in an otherwise reasonably well toddler
True or False?

A

True

71
Q

Septicaemia can present as fever with no obvious cause in an otherwise reasonably well toddler
True or False?

A

False

Bacteraemia is the presence of bacteria in the blood. Septicaemia is this but with an inflammatory immune response

72
Q

A 9 month boy presents to A&E with a history of recent gastroenteritis. His diarrhoea stopped 24 hour ago but he seems to have developed episodic periods of crying as in severe pain during which he may look ill and pale. In between, he seems to recover and look reasonably well. His temperature is 38oC. His abdomen is full and vaguely tender; there might be some fullness in the right middle/upper quadrant. There was no tenderness in the McBurney’s point and there was no obvious abdominal muscle rigidity. Is the following statement true or false regarding this case:

A heart rate of 80bpm is an indicator of good perfusion and circulation?

A

False

This is far too low for this child

73
Q

A 9 month boy presents to A&E with a history of recent gastroenteritis. His diarrhoea stopped 24 hour ago but he seems to have developed episodic periods of crying as in severe pain during which he may look ill and pale. In between, he seems to recover and look reasonably well. His temperature is 38oC. His abdomen is full and vaguely tender; there might be some fullness in the right middle/upper quadrant. There was no tenderness in the McBurney’s point and there was no obvious abdominal muscle rigidity. Is the following statement true or false regarding this case:

A heart rate of 190bpm reflects the increase in temperature?

A

False
This is far too high
• Expect to see a 10 bpm increase for every 1oC in adults
• Expect to see a 10-20 bpm increase for every 1oC in adults

74
Q

A 9 month boy presents to A&E with a history of recent gastroenteritis. His diarrhoea stopped 24 hour ago but he seems to have developed episodic periods of crying as in severe pain during which he may look ill and pale. In between, he seems to recover and look reasonably well. His temperature is 38oC. His abdomen is full and vaguely tender; there might be some fullness in the right middle/upper quadrant. There was no tenderness in the McBurney’s point and there was no obvious abdominal muscle rigidity. Is the following statement true or false regarding this case:

A period of observation with monitoring in hospital is the recommended course of action to allow the diagnosis to be confirmed?

A

False
Always consider appendicitis if there is an atypical presentation
• Diagnosis is intussusception “recurrent jelly stools”  too late, this is a sign of necrosis
(1) 9 months is peak age
(2) Episodic nature of pain
(a) Colic pain is spasmic and lasts for a few minutes
(b) Intermittent is days of pain then weeks of nothing
(c) Episodic in near normality with minutes of insufferable pain
(3) Cannot be felt in lower right quadrant (illeocaecal involvement that moves upwards)
(4) Vascular component require immediate management

75
Q

A 9 month boy presents to A&E with a history of recent gastroenteritis. His diarrhoea stopped 24 hour ago but he seems to have developed episodic periods of crying as in severe pain during which he may look ill and pale. In between, he seems to recover and look reasonably well. His temperature is 38oC. His abdomen is full and vaguely tender; there might be some fullness in the right middle/upper quadrant. There was no tenderness in the McBurney’s point and there was no obvious abdominal muscle rigidity. Is the following statement true or false regarding this case:

This baby should have an immediate imaging of the abdomen?

A

False

76
Q

A 9 month boy presents to A&E with a history of recent gastroenteritis. His diarrhoea stopped 24 hour ago but he seems to have developed episodic periods of crying as in severe pain during which he may look ill and pale. In between, he seems to recover and look reasonably well. His temperature is 38oC. His abdomen is full and vaguely tender; there might be some fullness in the right middle/upper quadrant. There was no tenderness in the McBurney’s point and there was no obvious abdominal muscle rigidity. Is the following statement true or false regarding this case:

This child is likely to have acute appendicitis and should be admitted and kept nil by mouth and started on IV infusion, to arrange a surgical review?

A

True

Management and diagnosis is through barium/air enema

77
Q

A 5 year old child with eczema and known nut allergy presents with a three day history of transient morning peri-orbital puffiness. He had a sore throat a couple of weeks beforehand. Is the following statement true or false?

A trial of anti-histamines for a few days is an appropriate initial management

A

False

Fluid retention. Morning facial puffiness that resolves once you adopt a vertical position

78
Q

A 5 year old child with eczema and known nut allergy presents with a three day history of transient morning peri-orbital puffiness. He had a sore throat a couple of weeks beforehand. Is the following statement true or false?

A referral to the allergist for allergy testing is appropriate

A

False

79
Q

A 5 year old child with eczema and known nut allergy presents with a three day history of transient morning peri-orbital puffiness. He had a sore throat a couple of weeks beforehand. Is the following statement true or false?

A trial of extension of the exclusion died to seeds and legumes is appropriate

A

False

80
Q

A 5 year old child with eczema and known nut allergy presents with a three day history of transient morning peri-orbital puffiness. He had a sore throat a couple of weeks beforehand. Is the following statement true or false?

A urine test should be obtained without delay

A

True

Most likely renal disease –> nephrotic syndrome

81
Q

A 5 year old child with eczema and known nut allergy presents with a three day history of transient morning peri-orbital puffiness. He had a sore throat a couple of weeks beforehand. Is the following statement true or false?

Imaging of the orbits and paranasal sinuses should be obtained without delay

A

False

82
Q

A previously healthy 7 year old child presents with a week history of coryza followed by cough and for the last couple of days has starting getting a bit breathless and developed a fever. On examination he was found to have crepitations on the right lung base. Is the following an appropriate action, true or false?
Obtain a chest x-ray

A

True

83
Q

A previously healthy 7 year old child presents with a week history of coryza followed by cough and for the last couple of days has starting getting a bit breathless and developed a fever. On examination he was found to have crepitations on the right lung base. Is the following an appropriate action, true or false?
Admit to hospital and start a course of Gentamicin

A

False

Gentamycin is for gram negative

84
Q

A previously healthy 7 year old child presents with a week history of coryza followed by cough and for the last couple of days has starting getting a bit breathless and developed a fever. On examination he was found to have crepitations on the right lung base. Is the following an appropriate action, true or false?

Admit to hospital for IV treatment with third generation Cephalosporin and Flucloxacillin

A

False

85
Q

A previously healthy 7 year old child presents with a week history of coryza followed by cough and for the last couple of days has starting getting a bit breathless and developed a fever. On examination he was found to have crepitations on the right lung base. Is the following an appropriate action, true or false?

Use oral Amoxicillin to treat the chest infection

A

True

86
Q

A previously healthy 7 year old child presents with a week history of coryza followed by cough and for the last couple of days has starting getting a bit breathless and developed a fever. On examination he was found to have crepitations on the right lung base. Is the following an appropriate action, true or false?

Use oral Co-Amoxiclav to treat the chest infection

A

False

Co-amoxiclav is a broad spectrum and is used in acute settings when you do not worry about antibiotic resistance

87
Q

A 16 year old girl presented with a 1 day history of nasal snuffliness, fever and fatigue. She also complained of headaches and pains in her claves and arms. Physical examination revealed an ill looking girl with fever at 39oC. There was no neck stiffness. She was also found to have a skin rash with generalised red spots. The “glass test” was negative (i.e. the spots do blanch on pressure). Is the following statement true or false in relation to this case?

Investigations to exclude calf deep venous thrombosis are appropriate

A

False

Unless on pill and presence of thrombophilic disorder (v. unlikely)

88
Q

A 16 year old girl presented with a 1 day history of nasal snuffliness, fever and fatigue. She also complained of headaches and pains in her claves and arms. Physical examination revealed an ill looking girl with fever at 39oC. There was no neck stiffness. She was also found to have a skin rash with generalised red spots. The “glass test” was negative (i.e. the spots do blanch on pressure). Is the following statement true or false in relation to this case?

In the absence of an obvious focus for infection, antibiotics shouldn’t be given

A

False

This is an ill looking girl. You must treat in order to cover anything more serious

89
Q

A 16 year old girl presented with a 1 day history of nasal snuffliness, fever and fatigue. She also complained of headaches and pains in her claves and arms. Physical examination revealed an ill looking girl with fever at 39oC. There was no neck stiffness. She was also found to have a skin rash with generalised red spots. The “glass test” was negative (i.e. the spots do blanch on pressure). Is the following statement true or false in relation to this case?

Tamiflu should be started following the appropriate swabs for virology

A

False

This illness is far too rapid and aggressive to be flu. Should be considered as secondary differential diagnosis

90
Q

A 16 year old girl presented with a 1 day history of nasal snuffliness, fever and fatigue. She also complained of headaches and pains in her claves and arms. Physical examination revealed an ill looking girl with fever at 39oC. There was no neck stiffness. She was also found to have a skin rash with generalised red spots. The “glass test” was negative (i.e. the spots do blanch on pressure). Is the following statement true or false in relation to this case?

Treatment for possible Meningococceamia should urgently be instated

A

True

91
Q

A 16 year old girl presented with a 1 day history of nasal snuffliness, fever and fatigue. She also complained of headaches and pains in her claves and arms. Physical examination revealed an ill looking girl with fever at 39oC. There was no neck stiffness. She was also found to have a skin rash with generalised red spots. The “glass test” was negative (i.e. the spots do blanch on pressure). Is the following statement true or false in relation to this case?

Use of oral Amoxicillin to treat maxillary sinus infection

A

True

92
Q

A 16 year old girl presented with a 1 day history of nasal snuffliness, fever and fatigue. She also complained of headaches and pains in her claves and arms. Physical examination revealed an ill looking girl with fever at 39oC. There was no neck stiffness. She was also found to have a skin rash with generalised red spots. The “glass test” was negative (i.e. the spots do blanch on pressure). Is the following statement true or false in relation to this case?

Measles is a likely cause if this girl has not been given the measles vaccine/MMR

A

False
The illness is too rapid. Measles is a disease with a prominent prodromal period of 3-4 days. Symptoms: conjunctivits, cough and rhinitis

93
Q

History of exposure to measles in the previous week is a contraindication for giving the MMR vaccine.
True or False?

A

False

MMR can be given exposure

94
Q

The anterior fontanelle is expected to close at 6-18 months of age
True or False?

A

True
• If closed before –> Primary craniosynostosis (can be caused thyrotoxicosis) leading to raised ICP. Secondary macrocephaly with no brain growth
• IF close after –> Hydrocephaly, Down’s syndrome, hypothyroidism

95
Q

Pneumococcal vaccine should not be administered to children with documented invasive pneumococcal infection in infancy
True or False?

A

False
There are 84 different strains of pneumococcus
• In small infants there is a poor response to encapsulated bacteria therefore we require immunisation

96
Q

Learning difficulties are a common cause of delay in gross motor development
True or False?

A
False
There are three main causes for delays
•	Normal variation
•	Lack of opportunity and training
•	Presence of physical or neurological abnormality
97
Q

Maculopapular rash and non specific symptoms/ Retro-auricular lymphadenopathy/ Haematuria/ Rapidly evolving acute severe febrile illness/ Target lesions/ Persisting fever and irritability for 5 days in a young child/ Diarrhoea & orthostatic hypotension are important features/ Sub-conjunctival haemorrhages/ Slapped cheeks/ Deafness/ Fever with no obvious focus resolving as skin rash appears/ Papulovesicular rash at different stages of evolution/ Abruptly developing skin rash/ Oral Penicillin V is usually effective/ Prominent prodromal symptoms

Match the following condition with the most appropriate answer:
Scarlet Fever

A

Oral Penicillin V is usually effective

98
Q

Maculopapular rash and non specific symptoms/ Retro-auricular lymphadenopathy/ Haematuria/ Rapidly evolving acute severe febrile illness/ Target lesions/ Persisting fever and irritability for 5 days in a young child/ Diarrhoea & orthostatic hypotension are important features/ Sub-conjunctival haemorrhages/ Slapped cheeks/ Deafness/ Fever with no obvious focus resolving as skin rash appears/ Papulovesicular rash at different stages of evolution/ Abruptly developing skin rash/ Oral Penicillin V is usually effective/ Prominent prodromal symptoms

Match the following condition with the most appropriate answer:
Reseola Infantium

A

Fever with no obvious focus resolving as skin rash appears

99
Q

Maculopapular rash and non specific symptoms/ Retro-auricular lymphadenopathy/ Haematuria/ Rapidly evolving acute severe febrile illness/ Target lesions/ Persisting fever and irritability for 5 days in a young child/ Diarrhoea & orthostatic hypotension are important features/ Sub-conjunctival haemorrhages/ Slapped cheeks/ Deafness/ Fever with no obvious focus resolving as skin rash appears/ Papulovesicular rash at different stages of evolution/ Abruptly developing skin rash/ Oral Penicillin V is usually effective/ Prominent prodromal symptoms

Match the following condition with the most appropriate answer:
Measles

A

Prominent prodromal symptoms

100
Q

Maculopapular rash and non specific symptoms/ Retro-auricular lymphadenopathy/ Haematuria/ Rapidly evolving acute severe febrile illness/ Target lesions/ Persisting fever and irritability for 5 days in a young child/ Diarrhoea & orthostatic hypotension are important features/ Sub-conjunctival haemorrhages/ Slapped cheeks/ Deafness/ Fever with no obvious focus resolving as skin rash appears/ Papulovesicular rash at different stages of evolution/ Abruptly developing skin rash/ Oral Penicillin V is usually effective/ Prominent prodromal symptoms

Match the following condition with the most appropriate answer:
German Measles

A

Retro-auricular lymphadenopathy

101
Q

Maculopapular rash and non specific symptoms/ Retro-auricular lymphadenopathy/ Haematuria/ Rapidly evolving acute severe febrile illness/ Target lesions/ Persisting fever and irritability for 5 days in a young child/ Diarrhoea & orthostatic hypotension are important features/ Sub-conjunctival haemorrhages/ Slapped cheeks/ Deafness/ Fever with no obvious focus resolving as skin rash appears/ Papulovesicular rash at different stages of evolution/ Abruptly developing skin rash/ Oral Penicillin V is usually effective/ Prominent prodromal symptoms

Match the following condition with the most appropriate answer:
Parvoviral Infection

A

Slapped Cheeks

102
Q

Maculopapular rash and non specific symptoms/ Retro-auricular lymphadenopathy/ Haematuria/ Rapidly evolving acute severe febrile illness/ Target lesions/ Persisting fever and irritability for 5 days in a young child/ Diarrhoea & orthostatic hypotension are important features/ Sub-conjunctival haemorrhages/ Slapped cheeks/ Deafness/ Fever with no obvious focus resolving as skin rash appears/ Papulovesicular rash at different stages of evolution/ Abruptly developing skin rash/ Oral Penicillin V is usually effective/ Prominent prodromal symptoms

Match the following condition with the most appropriate answer:
Mumps

A

Deafness

103
Q

Maculopapular rash and non specific symptoms/ Retro-auricular lymphadenopathy/ Haematuria/ Rapidly evolving acute severe febrile illness/ Target lesions/ Persisting fever and irritability for 5 days in a young child/ Diarrhoea & orthostatic hypotension are important features/ Sub-conjunctival haemorrhages/ Slapped cheeks/ Deafness/ Fever with no obvious focus resolving as skin rash appears/ Papulovesicular rash at different stages of evolution/ Abruptly developing skin rash/ Oral Penicillin V is usually effective/ Prominent prodromal symptoms

Match the following condition with the most appropriate answer:
Whooping Cough

A

Sub-Conjuntival Haemorrhages

104
Q

Maculopapular rash and non specific symptoms/ Retro-auricular lymphadenopathy/ Haematuria/ Rapidly evolving acute severe febrile illness/ Target lesions/ Persisting fever and irritability for 5 days in a young child/ Diarrhoea & orthostatic hypotension are important features/ Sub-conjunctival haemorrhages/ Slapped cheeks/ Deafness/ Fever with no obvious focus resolving as skin rash appears/ Papulovesicular rash at different stages of evolution/ Abruptly developing skin rash/ Oral Penicillin V is usually effective/ Prominent prodromal symptoms

Match the following condition with the most appropriate answer:
Chicken pox

A

Papulovesicular Rash at different stages of evolution

105
Q

Maculopapular rash and non specific symptoms/ Retro-auricular lymphadenopathy/ Haematuria/ Rapidly evolving acute severe febrile illness/ Target lesions/ Persisting fever and irritability for 5 days in a young child/ Diarrhoea & orthostatic hypotension are important features/ Sub-conjunctival haemorrhages/ Slapped cheeks/ Deafness/ Fever with no obvious focus resolving as skin rash appears/ Papulovesicular rash at different stages of evolution/ Abruptly developing skin rash/ Oral Penicillin V is usually effective/ Prominent prodromal symptoms

Match the following condition with the most appropriate answer:
Allergic Reactions

A

Abruptly developing skin rash

106
Q

Maculopapular rash and non specific symptoms/ Retro-auricular lymphadenopathy/ Haematuria/ Rapidly evolving acute severe febrile illness/ Target lesions/ Persisting fever and irritability for 5 days in a young child/ Diarrhoea & orthostatic hypotension are important features/ Sub-conjunctival haemorrhages/ Slapped cheeks/ Deafness/ Fever with no obvious focus resolving as skin rash appears/ Papulovesicular rash at different stages of evolution/ Abruptly developing skin rash/ Oral Penicillin V is usually effective/ Prominent prodromal symptoms

Match the following condition with the most appropriate answer:
Erythema Multiformae

A

Target Lesions

107
Q

Maculopapular rash and non specific symptoms/ Retro-auricular lymphadenopathy/ Haematuria/ Rapidly evolving acute severe febrile illness/ Target lesions/ Persisting fever and irritability for 5 days in a young child/ Diarrhoea & orthostatic hypotension are important features/ Sub-conjunctival haemorrhages/ Slapped cheeks/ Deafness/ Fever with no obvious focus resolving as skin rash appears/ Papulovesicular rash at different stages of evolution/ Abruptly developing skin rash/ Oral Penicillin V is usually effective/ Prominent prodromal symptoms

Match the following condition with the most appropriate answer:
Enteroviral Infections

A

Maculopapular rash and non specific symptoms

108
Q

Maculopapular rash and non specific symptoms/ Retro-auricular lymphadenopathy/ Haematuria/ Rapidly evolving acute severe febrile illness/ Target lesions/ Persisting fever and irritability for 5 days in a young child/ Diarrhoea & orthostatic hypotension are important features/ Sub-conjunctival haemorrhages/ Slapped cheeks/ Deafness/ Fever with no obvious focus resolving as skin rash appears/ Papulovesicular rash at different stages of evolution/ Abruptly developing skin rash/ Oral Penicillin V is usually effective/ Prominent prodromal symptoms

Match the following condition with the most appropriate answer:
Kawasaki Disease

A

Persisting fever and irritability for 5 days in a young child

109
Q

Maculopapular rash and non specific symptoms/ Retro-auricular lymphadenopathy/ Haematuria/ Rapidly evolving acute severe febrile illness/ Target lesions/ Persisting fever and irritability for 5 days in a young child/ Diarrhoea & orthostatic hypotension are important features/ Sub-conjunctival haemorrhages/ Slapped cheeks/ Deafness/ Fever with no obvious focus resolving as skin rash appears/ Papulovesicular rash at different stages of evolution/ Abruptly developing skin rash/ Oral Penicillin V is usually effective/ Prominent prodromal symptoms

Match the following condition with the most appropriate answer:
Meningococceamia

A

Rapidly evolving acute severe febrile illness

110
Q

Maculopapular rash and non specific symptoms/ Retro-auricular lymphadenopathy/ Haematuria/ Rapidly evolving acute severe febrile illness/ Target lesions/ Persisting fever and irritability for 5 days in a young child/ Diarrhoea & orthostatic hypotension are important features/ Sub-conjunctival haemorrhages/ Slapped cheeks/ Deafness/ Fever with no obvious focus resolving as skin rash appears/ Papulovesicular rash at different stages of evolution/ Abruptly developing skin rash/ Oral Penicillin V is usually effective/ Prominent prodromal symptoms

Match the following condition with the most appropriate answer:
Henoch-Schonlein Purpura

A

Haematuria

111
Q

Maculopapular rash and non specific symptoms/ Retro-auricular lymphadenopathy/ Haematuria/ Rapidly evolving acute severe febrile illness/ Target lesions/ Persisting fever and irritability for 5 days in a young child/ Diarrhoea & orthostatic hypotension are important features/ Sub-conjunctival haemorrhages/ Slapped cheeks/ Deafness/ Fever with no obvious focus resolving as skin rash appears/ Papulovesicular rash at different stages of evolution/ Abruptly developing skin rash/ Oral Penicillin V is usually effective/ Prominent prodromal symptoms

Match the following condition with the most appropriate answer:
Toxic Shock Syndrome

A

Diarrhoea and orthostatic hypotension are important features