Paediatrics Flashcards
Down’s syndrome presentation investigations
- Look for features of Down’s Syndrome (give examples)
- Karyotyping - Trisomy 21 (confirms diagnosis)
Health complications
• Cardiac echo - ASD, VSD, Tetralogy of Fallot
• Abdo USS - biliary/duodenal atresia
Down’s syndrome counselling
- What - Extra chromosome 21
- Re-occurence - higher age and genetics, can get genetic testing for both parents
- General care - LD, long-term care, health problems
- Heart disease, hearing problems (otitis media), vision problems (cataracts), hypothyroidism
Management
• MDT (paeds, GP, social worker, specialists (cardio, neuro, gastro etc.)
• Educate parents - support groups
• Early - physio, SALT
• Medium - specialist school, regular review
• Long - help with employment, living independently, fertility
Neonatal jaundice investigations
Bedside and bloods approach • Obs • Skin examination • Abdominal examination • Urine dip, MC&S
- Blood group
- DAT
- FBC and blood film
- G6PD
- Blood culture
- Bilirubin
- TSH
- LFT
Neonatal jaundice (hyperbilirubinaemia) management
- Phototherapy or exchange transfusion - refer to treatment threshold graph
- In phototherapy - eyes protected, blood samples taken regularly, can breastfeed and provide skin to skin contact, heated incubator to make baby feel comfortable
• Hydration e.g. encourage frequent breastfeeding
Asthma investigations
- Obs
- Peak expiratory flow rate
- Resp exam
- Consider spirometry
- Consider skin-prick testing
Asthma management
10 puffs of salbutamol through a spacer
Long-term:
- SABA
- Low-dose ICS
- Add LTRA
- Stop LTRA, start LABA
- Change ICS and LABA for MART (maintenance and reliever therapy)
- Increase ICS to moderate dose
- Specialist referral, consider high-dose ICS and trial of theophylline
Provide personalised asthma action plan from Asthma UK
Trigger avoidance
Ensure patient has own peak flow meter
Explain how to use inhalers
Bronchiolitis investigations
- Obs
- Resp exam - coughing, work of breathing, auscultation of lungs
- Nasopharyngeal swab would show RSV (not routine)
Bronchiolitis counselling
Reassure and discharge
• Common virus causing these symptoms, should resolve in 2 weeks
• Oxygen sats showing they are oxygenating well
• We think its mild and no medication needed, (palivizumab for high-risk preterm)
• Make sure they are feeding well, return if <75%
• Contagious - avoid other infants
Cow’s milk protein allergy investigations
- Obs
* Examination - skin (signs of anaphylaxis), abdominal, resp
Cow’s milk protein allergy management
IgE-mediated (minutes after ingestion)
• Allergy testing
• Paeds dietician referral
• Exclude cow’s milk protein from mother’s diet if breastfeeding
• Extensively hydrolysed formula if formula fed
• Elemental (amino acid) formula if that doesn’t work
Non-IgE mediated (2-72 hours after ingestion)
• Same as above but first 2 steps only if severe
Weaned
• Exclude CMP from diet
• Nutritional counselling from paeds dietician
• Regularly monitor growth
• Reintroduce into diet - follow Milk Ladder (Allergy UK)
Croup investigations
- Obs - A-E approach (RR, O2 sats, HR)
- Avoid examining throat
- Fluid balance assessment
- Resp exam
- Urine dip
• CXR - thumb and steeple sign, not usually done
Croup mild, moderate, severe management (according to Westley croup severity score)
All
• Oral dexamethasone (single dose for all patients, inhaled bec or IM dex if not possible)
• Analgesics
Mild
• No admission
• Safety net
Moderate
• Oxygen
Severe
• Admit
• Can give steroids while transported if travelling from GP
• Airway support (paeds, nurse, anaesthetists involved)
• O2 high flow via non-rebreathe mask
• Nebulised adrenaline (1 in 1000 1mg/ml), risk of rebound so close monitoring
Mild croup counselling
- Infection and inflammation of the airways
- Very common, have given some medication and should get better within 48 hours
- Keep caring at home with calpol, plent of fluids, and sitting upright
- Comfort child if distressed
- Come back to if symptoms don’t go away
- Call ambulance if drooling, trouble breathing, lethargic
Cystic fibrosis investigations
- Obs
- Examination
- Sweat test
- Genetic testing (and family) - delta F508 mutation
CF counselling
- Lifelong condition with recurrent resp infections and malabsorption
- Referred to specialist cystic fibrosis centre
- MDT approach
- Lungs - physio, mucoactive agents (lumacaftor - potentiator, ivacaftor - corrector)
- Infection - prophylaxis (staph aureus), acute infection (pseudomonas aerigunosa)
- Nutrition - enzyme tablets (creon), high-calorie diet, monitor growth
- Psychosocial - support for child and carers
Consider genetic testing if planning on having another child
Food allergy investigations
- IgE immunoassay
* Skin prick
Food allergy management/counselling
- Avoid allergens
- Mild - non-sedating antihistamines
- Severe - IM adrenaline and salbutamol if bronchospasm
- Educate on how to manage allergic attack (allergy action plan) and provide epi-pen
- Consider food challenge after 6-12 months of being symptom-free
- Consider in hospital if previous severe reaction
- Nuts and seafood allergies usually persist into adulthood
Pneumonia investigations
Bedside, bloods, imaging approach
- Obs
- Resp exam
- Urinalysis
- FBC and CRP
- Cultures
• CXR
Pneumonia management
- Amoxicillin/clarithromycin 5 days
- Co-amoxiclav high severity
- Antipyretics
- Adequate hydration
- Advise against parental smoking
- CHeck child regularly during day and night
- Return if RR increases, dehydration, or worsening fever
Hospital admission if O2 < 92%, grunting, marked chest recession, RR > 60
- Supplemental O2
- PO abx if tolerated, otherwise IV and review to switch back after 48 hours
Sore throat (pharyngitis and tonsillitis) investigation
- Obs
- Top to toe examination including throat, skin, cervical lymph nodes and ears
- Consider throat swab (rapid antigen test for group A strep)
Sore throat management
Group A strep confirmed (FeverPAIN 4/5 or Centor 3/4) or very unwell
- Phenoxymethylpenicillin (5-10 days) or clarithromycin
- Avoid amoxicillin in case mono
- Adequate fluid intake
- Antipyretics
- Salt water gargling, difflam
- Return to school 24 hours after taking abx / feeling well
Scarlet fever abx
Phenoxymethylpenicillin or azithromycin
Notify Health Protection Unit
Sinusitis treatment
< 10 days
• Antipyretics
• Nasal saline
• IN corticosteroid
> 10 days
• IN corticosteroid 14 days
• Back-up prescription (7 days) - 1. phenoxymethylpenicillin, 2. co-amoxiclav
Viral-induced/episodic wheeze management
Burst therapy
• 10 puffs of salbutamol using a high-volume spacer
• Puff every 30 seconds
Assess for response, repeat every 10-20 minutes
Discharge after 4 hours with no symptoms
Give salbutamol weaning regime (explain similar management to hospital, at home)
Whooping cough investigations
Bedside and bloods approach
• Obs
• Respiratory exam (cardio and abdo for completion)
• PCR of nasopharyngeal aspirate
• Consider IF antibody testing of perinasal swabs
• FBC, CRP, U&E
Whooping cough management
- ABx - macrolide e.g. clarithromycin (cough can still persist after ABx)
- Fluids
- Rest
- Calpol
- School exclusion until 48 hours after starting ABx or 21 days after onset of cough if not treated
- Prophylaxis - macrolide to close contacts, particularly if not immunised
- Safety net - come back if seizures, signs of respiratory distress, dehydration or weight loss
Coeliac investigations
Bedside, bloods, imaging approach
• Obs
• Abdo exam
• Faecal fat - Sudan Stain
- FBC, glucose, LFTs, U&E
- Vit D, Vit B12, folate, iron
- Calcium
- CRP/ESR
- IgA TTG ab
- EMA ab
• Jejunal/distal duodenal biopsy endoscopically
Coeliac counselling
- Inability to digest gluten
- Common but lifelong condition
- MDT - gastro, dietician, endo, speicalist nurse
- Dietician can help modify diet, how to manage in social settings and avoid cross contamination. Also iron supplementation.
- Annual review to monitor height and weight, review symptoms, assessment of diet
- Coeliac UK
Constipation investigations
- Abdominal examination - masses, tenderness
* Could do obs and further examination for completeness but not necessary
Constipation management
- Balanced diet with fibre and adequate fluid intake
- Regular toileting
- Behavioural interventions e.g. star chart
- Consider asking health visitor to support
Faecal impaction
- Osmotic laxative (movicol paediatric plain - polyethelene glucol 3350) for 2 weeks or until impaction resolves
- Stimulant laxative (senna)
• Can continue at maintenance dose until regular bowel habit established
Constipation management for infants not weaned and weaned
Not weaned
• Breast-fed: unsual, consider organic
• Bottle-fed: extra water between feeds, abdo massage, bicycling legs
Weaned
• Extra water, diluted juice
• Lactulose if not effective
Crohn’s investigations
Bedside, bloods, imaging approach
• Obs
• Abdominal examination (including mouth)
- FBC (anaemia)
- CRP
- Faecal calprotectin
- Vitamin B12 and vitamin D
- AXR - dilated loops, strictures
- Colonoscopy - inflamed, thickened, strictures/fistulae, skip lesions ‘cobble-stone’
- Biopsy - inflammation in all layers, increased goblet cells and granulomas
- Small bowel enema/barium study - Kantor’s string sign, ‘rose thorn’ ulcers
Crohn’s counselling
- Condition with unknown cause
- Digestive system is inflamed and problems absoring nutrients
- Life-long, risk of relapse - important we control it now
- Medication can be used to settle down the inflammation every time it flares up
- Will be seen by gastroenterologist
- No special diet, but may find certain foods will make it worse
- Recommend liquid diet during flare ups
- Complications - osteoporosis, erythema nodosum, bowel cancer
• Support: Crohn’s Colitis UK
How to induce remission in Crohn’s (first 2 options)?
- Corticosteroids
2. Aminosalicylates e.g. mesalazine
How to maintain remission in Crohn’s?
- Check thiopurine methyltransferase
- Give azathioprine (methotrexate 2nd line)
- Monitor for neutropaenia
- Monitor monthly - check for anaemia, vit deficiency