Paediatric Emergencies - Altered Consciousness, Epilepsy, Poisoning and Meningitis Flashcards

1
Q

What can cause altered consciousness?

A

Almost anything

Head trauma
Toxins
Infection
Metabolic causes
Brain tumour
Seizure etc
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2
Q

What is important to ask about on history if a child presents with altered consciousness?

A
Onset - Gradual or Sudden?
Previously unwell?
Feed
Trauma
PMH of seizures
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3
Q

How are children with altered consciousness managed?

A

A-E approach

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4
Q

What parts of the A-E approach are particularly important when assessing a child with altered consciousness?

A

Breathing pattern can indicate brain injury & smell breath for alcohol, toxins and ketones

C - admission bloods, clotting, lactate, culture and ABG

D - esp. pupils and glucose

E - Medical ID tag, signs of non blanching rash? Jaundice, fontanelles?

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5
Q

If the cause remains unknown after the A-E approach, what would be your next steps?

A

CT Head
EEG
Lumbar Puncture
Treat for meningitis/encephalitis if history fits

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6
Q

How would Raised Intracranial Pressure present in a child?

A
Bulging fontanelles
Loss of Consciousness
Unequal/unreactive pupils
Headache and vomit
Abnormal resp. pattern
Hypertension and bradycardia
Muscle flaccidity
Papilloedema
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7
Q

What are the contraindications to lumbar puncture in a child?

A
Reduced consciousness (GCS <13)
Septic shock
Likely invasive meningococcal disease
Signs of RICP
Focal neurology
Bleeding tendency
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8
Q

What is status epilepticus?

A

Any seizure lasting > 30 mins

OR

Series of seizures over a >30 min period without regain of consciousness

However for purpose of nice guidelines start treatment at 5 mins

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9
Q

What can cause status epilepticus?

A
Epilepsy
Fever
Febrile convulsion 
Head trauma
CNS infection
Poisoning
Metabolic disturbance
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10
Q

What is done immediately when a child is in status epilepticus?

A

A-E assessment
High flow O2
Check glucose

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11
Q

What is done after 5 minutes if the status epilepticus doesn’t resolve?

A
Buccal Midazolam 
300 mcg/kilo if <2 month
2.5mg/kg 3-11 months
5mg/kg 1-4 years
7.5mg/kg 5-9 years
10mg/kg 10-17 years

IV lorazepam
100mcg/kg <11 years old
4mg if 12-17years old

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12
Q

What would you do if status epilepticus isn’t resolving after 15 minutes even following treatment?

A

Call for senior help

IV Lorazepam 2nd dose

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13
Q

What would you do if status epilepticus hasn’t resolved after 25 minutes despite treatment?

A

Inform ITU

IV Phenytoin infusion - 20mg/kg

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14
Q

What would you do if status epilepticus hasn’t resolved after 45 minutes despite treatment?

A

Rapid sequence induction of anaesthesia

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15
Q

What investigations must be done following life supporting treatment for status epilepticus?

A
ABG
Calcium
Magnesium
Clotting
Anti-Epileptic drug level
EEG
Imaging
Lumbar Puncture
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16
Q

When do most cases of poisoning occur?

A

Toddler accidentally ingest something they shouldn’t

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17
Q

What can be other causes of poisoning in children?

A

Adolescents - self harm

Deliberate poisoning

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18
Q

What must you establish in the history?

A

Exactly what was ingested - name, brand, concentration
When they ingested it
How much they ingested

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19
Q

What investigations should be done following a child coming in with poisoning?

A
Urine toxicology screen
ABG
Carboxyhaemoglobin
ECG
Abdo X-Ray
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20
Q

What should the examination of a poisoned child include?

A

Inspection of oropharynx and vomitus

Assess level of consciousness

21
Q

What possible management options are there for swallowing?

A

Activated charcoal - 1g/kg within 1 hour of ingestion
Specific treatments for certain drugs and toxins
Gastric lavage
Ipecacuanha
Bowel irrigation

22
Q

What must be done if the poisoning is due to deliberate self harm?

A

Admit to hospital for psychiatric assessment

23
Q

What can Iron overdose cause and how is it treated?

A

Shock and Gut Haemorrhage

IV Desferrioxamine

24
Q

What can paracetamol overdose cause and how is it treated?

A

Liver failure

IV N-Acetylcysteine

25
What do salicylate overdose cause and how is it treated?
Widespread cellular damage and cardiac dysrhthmias Ethanol Dialysis if severe Alkalinize urine with bicarbonate Anti-arrhythmic
26
How is ecstasy overdose treated and what does it cause?
Hyperpyrexia and rhabdomyolysis and dysrhythmia Active cooling Benzodiazepines
27
What group of organisms normally causes meningitis?
Viruses
28
What do you do differently for viral meningitis than for bacterial?
Treat the same as you can't differentiate between them clinically
29
What are the main bacteria that cause meningitis is neonates?
Grou B Strep E Coli Listeria Monocytogenes
30
What are the main bacteria that cause meningitis in infants?
Neiserria Meningitidis | Strep Pneumoniae
31
What are the main bacteria that cause meningitis in children?
Neiserria Meningitidis Strep Pneumoniae Haemophilus Influenzae
32
What is meningitis?
Inflammation of the leptomeninges and CSF
33
In what ways can meningitis spread?
Direct spread - penetrate skin and skull or nasal mucosa | Haematological
34
What symptoms would make you wary of meningitis?
``` Headache Vomiting Stiff neck Photophobia Purpuric rash Altered mental state Kernig and Brudzinski's signs Pain Fever Cold extremities and long cap refill ```
35
What is Kernig's sign?
Can't straighten leg when hip is flexed to 90 degrees due to back pain
36
What is Brudzinski's sign?
Patient's hip and knees flex when neck is flexed
37
What investigations must you do if you query meningitis?
Bloods - CRP, FBC, Coag screen, PCR for N Meningitidis, glucose Lumbar puncture unless contraindicated Nasal swabs
38
When should you start treatment if you query meningitis?
Straight away! Don't wait for investigations
39
What signs on lumbar puncture are indicative of bacterial meningitis?
Raised protein, neutrophils | Low glucose
40
What signs on lumbar puncture are indicative of viral meningitis?
``` Protein raised or normal Glucose low (but not as low as bacterial) Raised lymphocytes ```
41
What are the main risk factors for neonatal meningitis?
Premature birth Low birth weight Traumatic delivery
42
How does neonatal meningitis present?
Non specific symptoms! ``` Raised or lower temp Respiratory distress Hypotension Bradycardia Poor feed ```
43
What are the short term complications of meningitis?
``` Acidosis Low K+, Ca2+, Mg2+ and glucose Coagulopathies Seizures Raised ICP ```
44
What are the long term complications of meningitis?
``` Hearing loss Scars from necrosis Limb loss Renal failure Psychosocial problems ```
45
How do you manage a patient with meningitis in the short term?
Resus with A-E approach IV Ceftriaxone for 7 days Dexamethasone IV Cefotaxime + Amox for <3 months
46
What antibiotic would you use for H Influenzae B and for how long?
IV Ceftriaxone for 10 days
47
What antibiotic would you use for S Pneumoniae and for how long?
IV Ceftriaxone for 14 days
48
What antibiotic would you use for L Monocytogenes and for how long?
IV Amoxicilin for 21 days | Gentamicin for 7 days
49
What antibiotic would you use for Gram -ve bacilli and for how long?
IV Cefotaxime for 21 days