Paediatric Dermatoloy Flashcards
Measles
- Caused by measles virus
- Spread by droplets
- 14-day incubation period
Presentation
- Fever, coryza and conjunctivitis
- Day 3 - rash appears on face (discrete, maculopapular, behind ears) then spreads down body and becomes confluent
- Cough present for whole illness
- Koplik spots - pathognomic but rarely seen
Management
- Notifiable disease
- Isolate child and stay off school for 4 days after rash begins
- Supportive treatment
- Safety netting (SOB, altered consciousness, seizures)
- Ribavarin for immunocompromised
- Vaccinate
Complications
- otitis media - most common complication
- Pneumonia
- Encephalitis and SSPE
Encephalitis
- Headaches, seizures and irritability which progresses to seizures and coma
- 15% mortality
- Long term sequelae including deafness, LD
Sub-Sclerosing Pan Encephalitis
- Occurs 7 years after measles infection
- Caused by a variant of measles which persists in the CNS
- Loss of neurological function which progresses to dementia and death
Scarlet fever
- Characteristic red rash associated with toxin-producing strain of Strep (usually Strep A)
Presentation
- Fine, punctate erythematous rash, most prominent in flexures
- 3 S’s of Scarlet fever:
1. Sparing of perioral area
2. Strawberry tongue
3. deSquamates
Investigations - none
Management
- Erythromycin
- Can return to school 24h after Abx start
Complications
- Rheumatic fever
Rubella
- Caused by rubella virus
- Incubation period 15-20 days
Presentation
- Red, maculopapular rash begins on face and then spreads centrifugally down torso and arms
- No fever (or low-grade)
- Rash wanes after 3-5 days
Investigations
- Serology - IgM ELISA done on all patients
- Repeat in convalescent phase because of false positives
Management
- No specific management, supportive only
- Should resolve in 7-10 days
- Avoid school for 4 days after rash starts, and avoid pregnant women
Complications
- Thrombocytopenia with haemorrhage
- Encephalitis
5th and 6th Disease
5th Disease - Erythema Infectiosum
- Caused by PB19 infection, most common in sprint
- 7 day coryza of fever, headache and myalgia
- Maculopapular red rash on cheeks which progresses to lace-like rash on trunk and limbs
6th Disease - Roseola Infantum
- Caused by HHV-6 and HHV-7
- There is 2-3 day coryza
- Generalised maculopapular rash begins as the fever wanes
Management of both
- Supportive care only
- Explain risk of febrile seizures
- No need to stay off school
Nappy rash
- Usually due to contact dermatitis due to irritant effects of urine
- Can also be atopic eczema, Candida infection
- In contact dermatitis the flexures are spared
Advice for parents
- High absorbency, well-fitting nappies
- Leave nappy off for as long as possible
- Change nappy as soon as possible after child has soiled
- Gently clean the area with water/fragrance free wipes and dry before fixing new nappy
- Use barrier cream e.g. Castor oil ointment (available OTC/in supermarkets)
Management of complications
- Inflammation - 1% hydrocortisone, only for infants >1 months, 7 days use max
- Suspected bacterial infection - oral flucloxacillin
- Suspected Candida infection - topical clomitrazole
Cradle cap
- Infant sebhorreic dermatitis
- Starts as an erythematous scaly eruption on the head
- There can be a sticky adherent covering on the head (Cradle cap)
- Rash may spread to face, axillae and napkin area
Management
- Advise patients that it is common and usually resolves spontaneously by 8 months
- They can use baby oil on the head, then use a soft brush to loosen the scales and wash with baby shampoo
- If symptoms persist, can give topical clomitrazole to be used 2-3/day until symptoms disappear
Eczema
- Common in children, usually presents in first year of life
- Itch-scratch cycle - the child feels an itch, scratches it, this exacerbates the rash
- Usually dry skin, excoriations and there can be lichenification
Management
- EMOLLIENTS!!
- Mild - 1% hydrocortisone for 48h
- Moderate - betametasone 0.025% for 48h for flare ups and 1% hydrocortisone for maintenance + non-sedating antihistamine – Follow up – if not better, check compliance, can refer to dermatology
Severe - Betamethasone 0.1% cream for flare ups and Bethamethasone 0.025% for face and flexures
Advice
- Atopic march
- Frequent and liberal use of emollients, even when skin is cleat
- Keep nails short
- If there are bowel symptoms, may refer to food allergy clinic for skin-prick testing
Guttate psoriasis
- usually presents following a bacteria/viral URTI
- There are red, scaly, drop-like plaques across the trunk and upper limbs
- These resolve over 3-4 months
- Tx with bland ointments
- Can recur in 3-5 years
Molluscum contagiosum
- Caused by poxvirus
- Presents with skin-coloured pearly papules, with central umbilication
- These are not harmful but can take 18 months to resolve
- No management needed
- Avoid sharing towels, clothing and baths
Pityriasis rosea
- Cause unknown but thought to be related to HHV infection
- There is an initial herald patch (red, scaly patch) which then develops into a widespread maculopapular rash
- May or may not be itchy
- Self-resolving in 4-6 weeks
Tinea
- Invasions of dead keratinised structures with dermatophyte fungi
- Can see fungal hyphae on skin scrapings microscopy
- Tinea capitis - systemic antifungals + selenium silphide shampoo
- Can otherwise give topical antifungal
Scabies
- Caused by Sarcoptes scabei
- Infection of the dermal layers down to the stratum corneum
- Presents with intense itching, 2-6 weeks after exposure
- In older children you may see burrows
- Clinical diagnosis
Treatment
- Permethrin 5% cream
- Apply to whole body, starting at neck and shoulders and then moving downwards
- Allow it to dry before putting on clothes
- After 8-12 hours, wash off
- Repeat treatment after 1 week
- Wash and tumble dry all clothing to decontaminate
- Treat close contacts
Pediculosis
- Pediculosis capitis = headlice infestation
- Treat with dimeticone 4% - apply and leave overnight, then wash out the next day
- Repeat treatment if symptoms are still there one week later
- Comb hair with fine-tooth comb to remove any live lice
Epidermolysis Bullosa
- Genetic condition with blistering of the skin and mucous membranes
- Blistering can be spontaneous or after minor trauma
- AD can be fatal whereas AR is milder
- There can be fusing of fingers and toes and limb contractures due to repeated healing and scarring
- Ulceration in mucosal membranes can lead to oesophageal strictures and stenosis
- Manage by avoiding minor trauma and treating secondary bacterial infections
Albinism
- Failure in the biosynthesis and metabolism of melanin
- Can be ocular, partial or oculocutaneous
- Eye problems - failure to develop fixation reflex, photophobia (constant frowning), pendular nystagmus
- Manage with sun protection and corrective glasses