Paediatric airway/respiratory conditions Flashcards

1
Q

Breakdown of causes of respiratory failure

A

Congenital and acquired

Extra-thoracic/intra-thoracic/Resp drive

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2
Q

Congenital causes of respiratory failure

A

Extra-thoracic:
- laryngomalacia
- Subglottic stenosis
- Tracheomalacia
- Vascular ring
- Cystic hygroma
- Craniofacial anomalies

Intra-thoracic
- Cogenital lung disorders (CDH, congenital lobar emphysema)
- CCAM
- Surfactant protein B & C deficiency syndromes
- Alveolar capillary dysplasia

Resp drive:
- SMA
- Congenital hypoventilation syndrome
- Congenital myotonic dystrophy
- Congenital myasthenia gravis
- Eventration of diaphragm
- Duchennes

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3
Q

Acquired causes of respiratory failure

A

Extra-thoracic:
- Infection (croup, RP abscess)
- Trauma
- Other - hypertrophied tonsils

Intra-thoracic
- Infection
- Heart failure (TAPVD)
- Asthma
- Near drowning
- ARDs
- BOOP
- Malignancy (T-Cell lymphoma)

Resp drive:
- CNS infection
- CNS trauma
- Drug overdose
- Guillain-Barre
- Myasthenia gravis
- kyphoscoliosis
- Flail chest
- Stroke

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4
Q

Organisms causing pneumonia in neonates

A

Neonates:

Transplacental/STROM
- Herpes simplex
- Toxoplasmosis
- Listeria
- Group B strep

Nosocomial
- Group B strep
- E coli
- Chlamydia
- Staph

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5
Q

Organisms causing pneumonia in children

A

Bacterial
- Strep pnemo
- Staph aureus
- mycoplasma
- Chlamydia
- Haemophilus
- Group A strep

Viral
- RSV
- Influenza A, B, H1N1
- Adenovirus
- Measles

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6
Q

VAP diagnosis

A

Change in colour and amount of secretions
Worsening gas exchange
+/- rising infection markers
Culture of infectious agent

Commonly pseudomonas, enterobacter cloacae & staph aureus

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7
Q

Empyema management

A

High dose IV abx for 3 weeks
Fibrinolysis:
- Small chest drain
- Urokinase 40000 IU in 40 ml 12 hourly
- clamp drain and encourage mobility
- Drain on suction
- Alteplase is an alternative
VATs surgery

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8
Q

Bronchiolitis

A

“Inflammation of the small airways of the lungs”

Infant <3 months at risk

Sx:
Antecedent URTI -> signs resp distress
Cough
Bilateral crepitations
Clinical air trapping and wheeze
Apnoea

Mx:
Oxygen
IV fluid. Restrict to 2/3 maintenance
?Ribavarin ?adrenaline nebs
CPAP
Invasive ventilation
ECMO

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9
Q

Mechanical ventilation in Bronchiolitis

A

May require high Insp pressure
PEEP 5-10 cmH2O
Low RR and increased I time
HFOV
Rarely ecmo

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10
Q

Asthma DDx

A

New dx - rule out foreign body
Mediastinal tumour
Congenital malformation
- vascular ring
- tracheal stenosis

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11
Q

Severe asthma exacerbation features for <5 years and >5 years

A

<5 years:
HR >130
Too breathless to talk or feed
RR > 50

> 5 years:
Too breathless to talk
PEFR <50%
HR >120
RR >30

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12
Q

Life threatening asthma signs

A

Confusion, exhaustion
PEFR <33%
Silent chest or poor resp effort
Cyanosis

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13
Q

Admission to PICU with asthma

A

Deteriorating PEFR
Persistent or worsening hypoxia
Hypercapnia
Falling pH
Exhaustion, poor respiration

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14
Q

PICU management of asthma

A

IV hydrocortisone 4mg/kg
IV salbutamol
(5mcg/kg for 1 hour then 1mcg/kg/hr)
IV aminophyline
5mg/kg bolus then 1mg/kg/h infusion
Magnesium
50mg/kg over 20min
Consider NIV

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15
Q

Intubating asthmatics

A

Good IV access
Fluid bolus 10ml/kg
Ketamine RSI
Cuffed tube
AVOID RAPID BAGGING
Manual decompression

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16
Q

Ventilation for asthmatics

A

PC preferably, 4-8ml/kg TV
Rate well below age average
Insp 1.0-1.5s
I:E ration 1:3 - 1:5
Aim to limit PIP <35 cmH2O
Avoid high PEEP

17
Q

Non-ventilatory issues for intubated asthmatics

A

Sedation & paralysis
- adequate sedation with morph/midaz or ketamine
- Avoid prolonged paralysis -> pancuronium or vecuronium

Continue bronchodilator therapy

18
Q

Referactory hypoxaemia mx in intubated asthmatics & rescue treatments

A

CXR/POCUS - atelectasis/pneumothorax
Hypovolaemia can worsen V/Q mismatch
Trial spontaneous breathing

Rescue treatments:
- Ketamine infusion
- volatile anaesthetics
- magnesium infusion
- BAL or nebulized DNAse for secretions
- proning
ECMO

19
Q

Diagnosis of ARDs in paediatrics

A

American-european consensus conference definition

Oxygenation
- ALI P/F ration <300
- ARDS P/F ration <200
CXR
- bilateral infiltration
Pulmonary artery pressure
- <18 mmHg if measured
- no signs of increased left atrial pressure

20
Q

ARDs management

A

Intubated and ventilate +/- mechanical support
Prevent overload
Adequate sedation and pain relief
nutritional support