Pacop

Question 1

parabens (preservative ) increase preservative property by?

Answer 1

Increasing MW

Question 2

Sodium pump

Answer 2

Ion channel

Question 3

Approach in drug discover wherein there is already an existing drug that can be used to identify a new lead compound?

Answer 3

Random screening

Question 4

Radical reactions may also proceed using this reagent:

Answer 4

Hydrogen Peroxide
(H2O2)

Question 5

The addition of hydrogen molecule to an alkene is catalyzed by the metal ?

Answer 5

Palladium

Question 6

Methoxybenzene is AKA:

Answer 6

Anisole

Question 7

A compound used to synthesize primary alcohols:

Answer 7

Propane

Question 8

A cephalosporin excreted in bile:

Answer 8

Ceftriaxone

Question 9

Preservative used for molds:

Answer 9

Methylparaben

Question 10

A functional group being modified if formulation into a salt is needed:

Answer 10

Carbonyl

Question 11

Compound used to identify the Partition coefficient in -vitro

Answer 11

N-octanol

Question 12

The total affinity of the ligand to its receptor

Answer 12

Avidity

Question 13

Dimethylbenzene is aka:

Answer 13

Xylene

Question 14

Benzen undergoes what type of reaction?

Answer 14

Electrophilic substitution

Question 15

which of the following carbocation intermediate is the most stable?

Answer 15

Tertiary

Question 16

Regioselectivity of an organic reaction in which the orientation of the substituents stabilizes the product is governed by:

Answer 16

Markovnikov’s Rule

Question 17

Enol is not a stable compound because it undergoes

Answer 17

Tautomerization

Question 18

Acetylation of morphine yields:

Answer 18

Heroin

Question 19

Primidone is a product that is converted into:

Answer 19

Phenobarbital

Question 20

In phenols, substitution at _______ position increases bactericidal activity

Answer 20

Para (4)

Question 21

C3H6O can be a/an

Answer 21

Ketone/Ether

Question 22

Zero order dug metabolism:

Answer 22

Saturable Kinetics

Question 23

Thiopental is being converted into pentobarbital upon metabolism by what pathway?

Answer 23

Desulfuration

Question 24

First cass of antivetroviral dugs and first type of dugs for HIV to be available:

Answer 24

NRTI
(Nucleoside Reverse
Transcriptase Inhibitor)

Question 25

HIV drugs also used for Hepatitis B infection:

Answer 25

Lamivudine

Question 26

metabolic disorder is commonly seen in what type of HIV drugs?

Answer 26

Protease inhibitors

Question 27

coordination of what metal in tetracycline sticture increases its activity?

Answer 27

Palladium

Question 28

What cephalosporin can cause blood brain barrier?

Answer 28

Cefuroxime

Question 29

this agent is used to chelate copper in which an excess amount causes wilson's disease:

Answer 29

Penicillamine