pack Flashcards
What are the carries for the outer and inner layers of the mitochondria?
What are the 5 co-enzymes in the pyruvate dehydrogenase complex?
1.Thiamine pyrophosphate (B1)
2.Lipoic acid
3.CoA (B5, pantothenic acid)
4.FAD (B2, riboflavin)
5.NAD+ (B3, niacin)
(The lovely Coenzymes for nerds)
What is thiamine converted to?
Thiamine pyrophosphate
Thiamine is a co-factor for what 4 enzymes?
Pyruvate dehydrogenase complex
What are the two types of thyamine defciency?
Beriberi and wernicke-korsakoff syndrome
periperi chicken with thyme
What are the types, causes and symptoms of beriberi thymine def?
Cause: malnutrition
What are the causes and symptoms of wernicke korsaksofft hymine def?
What is FAD synthsized from and what is it added to?
Flavin: the flavor makes you fat
Ribo: bc atp has adenosine and ribose sugar
What is NAD synthsized from?
Niacin: like نعسان and nad like نام
tryptophan: bc when you sleep you want a fan
What is CoA synthsized from and what does it accept?
Coenzyme A: So it is the co of actyl
Pantothenic: bc A looks like two legs so pants and they are thin
What does lipoic acid bind to? What is it a co factor for? What is it inhibted by?
Little Ants Inhabit Arsenic
(they have arsenals)
What activates pyruvate dehydrogenase?
What enzymes regulate PDH by phosphorlation? which one is active?
What is the rate limting step in the krebs cycle? What is it regulated by? What does it produce?
Isocitrate dehydrogenase
ADP and Ca++ activate it
Isocitrate to α-ketoglutarate
What are the co factors for a-ketoglutarate dehydrogenase?
The lovely co-enzymes for nerds
Thiamine pyrophosphate
Lipoic acid
CoA
FAD
NAD+
What does a-ketoglutrate dehydrogenase yield?
Succinyl CoA
Bc you become succesful after Keto
What happens in succinyl-CoA synthetase?
GTP is synthesized
And succicnate is produced
It is substrate level phosphorylation
What happens in succicnate dehydrogenase?
Succicnate is converted to fumarate
Requires FAD
bc when they lose more weight they become high rate
