pack Flashcards
What is the ferrous form of iron
fe+2
(bc the word is أنعم)
What is the ferric form of iron?
fe+3
(bc the word is أخشن)
What form of iron can our body absorb?
The ferrous form, (Fe +2)
(bc it is smaller, so it is easier to absorb)
What type of iron do most foods contain?
Ferric (fe+3)
What form of iron is stored and transferred in our body
Ferric (Fe+3)
What is iron called in the blood?
Hemoglobin
What is iron called in the muscles?
myoglobin
What is ferritin?
The storage form of iron (fe+3)
What is transferrin?
A protein that transfers iron inside the blood stream (fe+3)
What is the most sensitive marker that we focus on when mesuring blood iron levels?
ferritin
What are the different ways to assess the iron levels of the blood?
Serum Iron
Ferritin
Transferrin
Transferrin saturation
What happens to serum iron, ferrtin, and transferrin levels when a patient has iron deficiency.
Serum iron: decrease
Transferrin: increase
Ferritin: decrease
What does ferroportin do?
ferroportin is used by cells to release iron from the inside of the cell to the outside.
What does haptoglobin do?
it catches hemoglobin that is released from cells that rupture.
(it’s like it’s saying hato llglobin)
What does hemopexin do
catch heme
(it pexs up the heme)
What does hepcidin do?
Prevents the iron from getting released into the blood by inhibting/degrading ferroportin
What does Dcytb (ferrireductase) do?
convert fe 3+ to fe 2+
What does hephastin do?
It converts fe 2+ to fe +3
(it makes it phat)
What does erythropoiten do?
Controls erythroferrone.
What does erthythroferrone do?
Lowers the production of hepcidin which in turn increases blood iron levels.
What is hemosiderin?
It is partially digested ferritin
What is DMT1
Divalent metal transporter 1
It is the iron receptor
What is a condition that causes iron overload?
hereditary hemochromatosis
What does hereditary hemochromatosis do?
Causes oxidation bc of iron overload which damages the organs.
