PACES viva Qs Flashcards
Contents of inguinal canal
Ilioinguinal nerve
Genital branch of genitofemoral nerve
Round ligament or spermatic cord
Contents of femoral canal
Efferent lymphatic vessels
LNs
Borders of inguinal canal
Roof: internal oblique and tranversus abdominis
Floor: inguinal ligament
Anterior: aponeurosis of external oblique
Posteriorly: transversalis fascia
Borders of femoral canal
Medially: lacunar ligament
Laterally: femoral vein
Anteriorly: inguinal ligament
Posteriorly: Pectineus muscle
What is Gardner’s syndrome?
Syndrome within spectrum of familial polyposis coli syndromes Includes: = Adenomatous polyposis of large bowel = Multiple osteomata of skull = Desmoid tumours = Epidermoid cysts
Borders of anterior triangle of neck
Midline
Ant border of sternocleidomastoid
Mandible
Borders of posterior triangle of neck
Posterior border of sternocleidomastoid
Clavicle
Anterior border of trapezius
Causes of cervical lymphadenopathy?
LIST Lymphoma/leukaemia Infection Sarcoidosis Tumours (primary or secondary)
What nerve may be damaged in posterior triangle?
Spinal accessory nerve
Causes of proximal myopathy
Endocrine: COT
- Cushings
- Osteomalacia
- Thyrotoxicosis
Neuromuscular
- Duchennes/Beckers
- Myotonic dystrophy
MSK
- PMR
- Myositis
Causes of peripheral neuropathy
Sensory
- Diabetes
- B12 deficiency
- Hypothyroidism
- ETOH
- Uraemia
- Leprosy
- Amyloidosis
- Iatrogenic eg drug-induced (Isoniazid), amiodarone
Motor
- GBS
- Pb poisoning
- Porphyria
- Hereditary sensorimotor polyneuropathies eg charcot-marie-tooth
- Diphtheria
What are the ECG changes in first degree heart block?
Prolongation of PR interval but no dropping of QRS
What are the ECG changes in Mobitz type I heart block?
Successive prolongation of PR interval until QRS dropped
What are the ECG changes in Mobitz type II heart block?
Fixed PR interval with some p waves not conducted to QRS complexes in certain ratio
What are the ECG changes in third degree heart block?
Complete dissociation between atrial and ventricular contraction
SRS pattern in V1 and RSR pattern in V6
LBBB
RSR pattern in V1 and SRS pattern in V6
RBBB
Most specific marker for pericarditis on ECG?
PR depression
ECG findings posterior MI?
Tall R waves V1-V3
What does vitamin B12 deficiency cause?
Subacute degeneration of spinal cord
Causes of SIADH?
Malignancy
- Small cell lung Ca
(pancreas/prostate also possible)
Neurological
- Stroke
- SAH
- Subdural haemorrhage
- Meningitis/encephalitis/abscess
Infection
- TB
- Pneumonia
Drugs:
- Carbamazepine
- Sulphonyureas
- SSRIs
- Tricyclics
Why does hyponatraemia need to be corrected slowly?
Risk of central pontine myelinolysis
What are the causes of a collapsing pulse?
Aortic regurgitation
Hyperkinetic states eg thyrotoxicosis, anaemia, fever, pregnancy, exercise
PDA
What are the causes of pulsus paradoxus?
Severe asthma
Cardiac tamponade
What are the causes of pulsus alternans?
Severe LVH
What CLASS of drug should be prescribed for a patient with diabetes and hypertension who is found to have microalbuminuria?
ACEi
What effect do ACEi have on urinary albumin excretion?
Decrease it
Most likely cause of otitis media?
Strep pneumoniae
What are some consequences of acromegaly?
endocrine - impaired glucose tolerance, DM cardio - LVH, HTN, cardiomyopathy msk - carpal tunnel syndrome gi - recurrent GI polyps other - obstructive sleep apnoea
Examination findings for otitis media
Bulging tympanic membrane
Loss of light reflex
possible perforation and pus
Muscles innervated by trochlear nerve?
Superior oblique for abduction and depression
Muscles supplied by CNVI?
Abducens supplies lateral rectus for abduction of eye
Muscles supplied by CNIII?
Medial rectus Superior rectus Inferior rectus Inferior oblique LPS
What are some causes of paralytic strabismus?
CN III/IV/VI palsy
What are some causes of ptosis?
Unilteral
CNIII palsy/Horner’s
Mechanical eg trauma or xanthelasma
Bilateral
MG, congenital, Myotonic dystrophy, senile
What is true ptosis caused by?
LPS weakness
What does the screening programme for colorectal cancer involve?
Screening every 2 years for 60-74 year olds
What malignancy is H pylori associated with?
MALToma
What is a skin flap?
Consists of tissue or tissues transferred from one site of the body to another whilst maintaining a continuous blood supply through a vascular pedicle
What is a graft?
Transfer of skin from a donor site to a recipient site independent of a blood supply
What causes lid lag?
Overstimulation of levator palpebrae superioris
What are the features of Grave’s disease o/e?
Diffuse goitre Thyroid acropachy Eye disease Proximal myopathy Pretibial myxoedema
What are the causes of diffusely enlarged thyroid gland?
Simple Colloid goitre
Grave’s
Thyroiditis
Findings for otoscopy and tympanometry for glue ear?
ear drum dull + retracted, fluid level visible
flat tympannogram
What are the causes of vertigo?
Peripheral/vestibular
- Meniere’s
- BPPV
- Labyrinthitis
Central
- Vestibular Schwannoma
- MS
- Stroke
- Head injury
- Inner ear syphilis
Drug
- Vancomycin
- Loop diuretics
- Metronidazole
- Co-trimoxazole
Definition of a hernia
a protrusion of a viscous out of a containing cavity
Hypocalcaemia on ECG
Prolongation of QTc segment
Alternating amplitude of QRS on ECG
Electrical alternans - associated with pericardial effusion
Hypercalcaemia on ECG finding and causes?
QTc shortening, if severe J waves -
hyperparathyroidism or malignancy?
Hypokalaemia findings on ECG?
T wave inversion, QTc prolongation and visible U waves i
Hyperkalaemia findings on ECG?
tall, peaked T waves, QTc shortening and ST-segment depression
What criteria is used for pleural effusion and what are the cutoffs?
Lights criteria to determine whether transudate or exudate
<30 = transudate
>30 = exudate
Use criteria if 25-30, includes ratio of serum to aspirate protein and LDH - ie higher protein and LDH content the more likely its exudative
What are some causes of a transudate pleural effusion?
Nephrotic syndrome CCF Liver failure ie cirrhosis Myoexedema Meig's syndrome eg benign ovarian tumour, ascites, right sided pleural effusion
What are some exudative causes of pleural effusion?
Infection eg pneumonia, fungal infection, lung empyema, TB Malignancy PE Pancreatitis Trauma
What is the classification used for heart failure?
New York Heart Association Classification
- No limitation on activity
- Comfortable at rest, dyspnoea on ordinary activity
- Marked limitation of normal activity
- Dyspnoea at rest
What are some causes of a normal anion gap acidosis?
Addisons
GI losses eg due to diarrhoea or fistula
Renal tubular acidosis
What are some causes of a raised anion gap acidosis?
Ketones: DKA, Ethanol
Lactate: shock, sepsis, hypoxia
Urate: renal failure
What scores are used to assess Upper GI bleeding?
Blatchford - pre-endoscopy
Rockhall - post-endoscopy -> to guide prognosis eg rebreeding, mortality
What mode/plane of imaging is needed for scaphoid fractures?
Ulnar deviation AP view
What is the pattern of injury in a Colles fracture?
Dorsal displacement of distal radius
What is the pattern of injury in a Smith’s fracture?
Anterior/volar displacement of radius
Blood finding with Paget’s disease of bone?
Solitary rise in ALP
What are some common causes of carpal tunnel syndrome?
Idiopathic Pregnancy Rheumatoid arthritis Oedema Lunate fracture
Associated with:
Hypothyroidism
Diabetes
Heart failure/COCP
Examination findings in CTS
Weakness of abductor pollicis brevis
Wasting of thenar eminence
Muscles supplied by median nerve
LOAF
- Lateral two lumbricals
- Opponens pollicis
- Abductor pollicis brevis
- Flexor pollicis brevis
Non-traumatic causes of AVN of femoral head?
Diabetes
HIV
Lupus
Chronic renal failure
Late systolic murmur?
Mitral valve prolapse
Coarctation of aorta
What score can be used to assess mortality in ACS pts?
GRACE score - 6mth mortality in pts with ACS
? Diagnosis if ECG shows a shortened PR interval and wide QRS complexes associated with a slurred upstroke seen in lead II.
WPW
What are some causes of hypoglycaemia?
Exogenous drugs eg sulphonylureas or insulin Pituitary insufficiency Liver failure Addison's Insulinoma Non-pancreatic neoplasms
Causes of clubbing?
Cardiac causes
cyanotic congenital heart disease (Fallot’s, TGA)
bacterial endocarditis
atrial myxoma
Respiratory causes lung cancer pyogenic conditions: cystic fibrosis, bronchiectasis, abscess, empyema tuberculosis asbestosis, mesothelioma fibrosing alveolitis
What is an abnormally large drop in blood pressure on inspiration called and what does it signify?
Pulsus paraxodus
- characteristic of cardiac tamponade
What is a raised JVP with inspiration called and in what condition is it found?
Kussmaul’s sign
- constrictive pericarditis
Drugs that can induce intracranial hypertension?
COCP Tetracyclines Steroids Vitamin A Lithium
Widespread saddle-shaped ST elevation with PR segment depression indicates…
Pericarditis
Q waves in lead II, III, aVF indicates …
Previous inferior MI
Downsloping ST depression (‘reverse tick’ sign) indicates…
Digoxin toxicity
Deep T wave inversion or biphasic T waves in V2-V3 indicates…
LAD stenosis
ECG findings
left ventricular hypertrophy
non-specific ST segment and T-wave abnormalities, progressive T wave inversion may be seen
deep Q waves
HOCM
What are some of the indications for ORIF in fracture management?
failed cons management intra-articular # multiple # same bone bilateral same # open #
Methods of non-operative fixation ortho?
Non-rigid eg slings
POP
Bracing
Continuous traction eg collar and cuff
What are some general fracture complications?
Anaesthetic
Intra-op
Early / late post-op
Complications of fracture ortho specific?
Intra-op: visceral damage or NV injury
Early: infection, compartment syndrome, fat embolism, VTE
Late: malunion, AVN, joint loosening, fracture at site, complex regional pain syndromes
From what fractures is compartment syndrome most likely?
Tibial shaft
Supracondylar
Complications of compartment syndrome?
Rhabdomyalysis
Volkmann’s contractures
What are the 5 causes of non-union of a fracture?
- ischaemia
- infection
- inter fragmentary strain increased
- intercurrent disease
- interposition of tissue between fragments
3 sites prone to AVN?
Femoral head
Scaphoid
Talus
How can you differentiate a fat embolism from a PE?
Neuro s/s
- confusion
- agitation
- retinal haemorrhages
- fat globules
ECG: inverted P wave in lead I, right axis deviation, and loss of R wave progression
dextrocardia
?kartagener’s syndrome
Features of IBD related to disease activity?
Arthritis: pauciarticular, asymmetric
Erythema nodosum
Episcleritis
Osteoporosis
What are some absolute and contraindications to thrombolysis?
Absolute
- Haemorrhage/active bleeding
- GI bleeding within last 3wks
- Prev intracranial haemorrhage
- Pregnancy
- Intracranial neoplasm
- Intracranial infarct in last 3mths
- Varices
- Uncontrolled HTN
Relative
- Concurrent anticoag
- Major trauma or surgery in last 2wks
- Active diabetic haemorrhage retinopathy
- Suspected intracardiac thrombus
How can you differentiate a bulbar palsy from a pseudo bulbar palsy?
Bulbar = LMN signs CN9-12
Pseudobulbar = UMN signs CN5/7, 9-12
eg jaw jerk bulbar = absent, pseud-bulbar = brisk
CT report describes a hypodense collection around the convexity of the brain that is not limited to suture lines - what is it?
Chronic subdural haematoma
Note hypooodense rather than hyper as chronic not acute
What limits extra-dural haematomas?
Suture lines
left homonymous hemianopia - where is the lesion?
right optic tract
homonymous quadrantanopia inferior - where is the lesion?
optic radiation - parietal lobe
homonymous quadrantanopia superior - where is the lesion?
optic radiation - temporal lobe
incongruous visual field defects - likely place of lesion?
optic tract
congruous visual field defects - likely place of lesion?
optic radiation or occipital cortex
Congenital conditions associated with epilepsy
Mitochondrial disease
Tuberous sclerosis
Cerebral palsy
What is a eye sign of Vestibular Schwannoma?
Loss of corneal reflex
What are your differentials for sudden onset headache?
SAH
Pituitary apoplexy
What marker in the blood do central seizures raise which can distinguish them from absence?
Prolactin
In addition to focal seizures, what can carbamazepine be used to treat?
Bipolar disorder
Trigeminal neuralgia
Contents of the lateral wall of the cavernous sinus?
Oculomotor nerve
Trochlear nerve
Ophthalmic branch of trigeminal nerve
Maxillary nerve of trigeminal nerve
Contents of cavernous sinus?
Internal carotid artery
Abducens nerve
Sudden onset headache, visual field defects + BP changes or sth similar? What immediate management needs to be given?
Pituitary apoplexy
Replace steroids immediately
In what seizures is carbamazepine CI in?
Myoclonic
Absence
CT head - multiple ring enhancing lesions
Toxoplasmosis
CT head - single enhancing lesion
TB
Findings of RA on X-ray?
LESS
- Loss of joint space
- Erosions
- Soft tissue swelling
- Osteopenia
later - subluxation
Adverse signs in cardiac arrest?
Hypotension
Myocardial ischaemia
Syncope
Heart failure
Definitive treatment for acute glaucoma
Laser peripheral iridiotomy
Normal QT segment
less than 430 ms in males
less than 450 ms in females
Normal PR interval
120-200ms
Causes of cavitation on CXR?
abscess, infective eg staph aureus pneumonia, klebsiella, pseudomonas TB vasculitis eg Wegner's granulomatosis SCC PE Rheumatoid Aspergillosis
Causes of proximal myopathy
Inherited: Duchenne’s muscular dystrophy, Becker’s, myotonic dystrophy
Endocrine: Cushings syndrome, thyrotoxicosis, hyperparathyroidism, diabetic amyotrophy
Inflammatory: polymyositis, rheumatoid
Metabolic: osteomalacia
Malignancy: Lambert-Eaton syndrome, paraneoplastic
Drugs: ETOH, steroids
Lateral epicondylitis - what movement is most painful?
Wrist extension on resistance with elbow extended or supination of forearm
Thyroid scan - globally reduced uptake of iodine-131 - cause?
Qe Quervain’s
Most specific ECG marker for pericarditis?
PR depression
Most common tumour causing bony mets
1) Prostate
2) Breast
3) Lung
Most common sites of bony mets
1) Spine
2) Pelvis
3) Ribs
4) Skull
5) Long bones
Causes of a third nerve palsy
Medical: Diabetes Vasculitis -> GCA, SLE MS Raised ICP -> herniation through tentorial notch
Surgical - pupil dilated:
Posterior communicating artery aneurysm
Cavernous sinus thrombosis
Features of COPD on CXR
Flattened hemidiaphragms
Hyperinflation
Hyperlucent lung fields
What are the complications of acromegaly?
Cardiomyopathy
HTN
Diabetes
Colorectal cancer
Considerations for transvenous pacing?
complete heart block with broad complex QRS
recent asystole
Mobitz type II AV block
ventricular pause > 3 seconds
Pyrazinamide SEs
gout
hepatitis
What is myasthenia gravis?
An autoimmune disorder characterised by insufficient functioning of nicotinic ACH receptors leading to fatiguability
In what cancers is Lambert eaton syndrome seen?
SCLC
Breast
Ovarian
How does Pulmonary fibrosis present on a CT?
Honeycombing
Where do lung mets commonly come from?
Breast Prostate Renal Colorectal Bladder
Where do lung mets commonly come from?
Renal
could also be choriocarcinoma or prostate
Causes of cavitating lesions
Cancer e.g. SCC Autoimmune e.g. RA nodules, Wegener’s Vascular e.g. PE Infection e.g. upper zone TB, pulmonary abscess (Staph aureus, Klebsiella, Pseudomonas), fungi (Aspergilloma, histoplasmosis, coccidiomycosis) Trauma Youth e.g. bronchogenic cyst
Causes of hilar lymphadenopathy
TB
Sarcoid
Lymphoma
Causes of widened mediastinum
Thoracic aortic aneurysm Thyroid/retrosternal goitre Thymoma Teratoma Lymphoma
Causes of globular heart
Pericardial effusion
Cardiac tamponade
Tetralogy of Fallot (boot shaped)
Causes of Beck’s triad
Hypotension
JVP
Muffled heart sounds
How do you tell an NG tube is well placed?
1) pH testing via aspiration <4
2) CXR: should bisect carina at T4