Oxygenation Dynamics Flashcards

1
Q

What is normal minute ventilation Range?

A

4-8 L/min (5L/min Average)

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2
Q

What is normal Cardiac Output (CO)?

A

4-8 L/min (5.5L/min Average)

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3
Q

What is Q?

A

Abbreviation for Cardiac Output

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4
Q

What is venous admixture V/Q mismatch?

A

Lack of available oxygen to the alveolar membrane

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5
Q

What is Shunting?

A

Any type of block that inhibits gas exchange “A Shunt is where blood flows past alveoli with no gas exchange occurring”

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6
Q

What is the first stage of shock?

A

Uncompensated Respiratory Alkalosis

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7
Q

What is deadspace ventilation?

A

Lack of perfusion to part of the lung tissue which is being ventilated. ie: pulmonary embolism, cardiogenic shock, etc.

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8
Q

What is first line therapy for venous admixture?

A

Supplemental Oxygen Therapy

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9
Q

What are the goals of Aerobic Respiration?

A

Production of ATP

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10
Q

What is required for aerobic respiration (4 things)?

A

Adequate Oxygen
Ability to extract O2 and move into the cell (hemoglobin)
Ability to move oxygen (Cardiac Output)
Ability to move O2 into the cell

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11
Q

What is the normal amount of hemoglobin in an adult?

A

12-15g/dl

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12
Q

Which patients have lower glycogen stores?

A

Pediatrics and Geriatrics

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13
Q

What is Glycoloysis?

A

The first stage of ATP creation, converts glucose to pyruvate

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14
Q

What is Lactate?

A

Product of glycolysis,
Indication of stress (a need for more ATP), not a direct indication of tissue hypoxia

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15
Q

What are the end products of the Krebs Cycle?

A

2 ATP
6 CO2
6 NADH
2 FADH

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16
Q

What is Oxidative Phosphorylation (Electron Transport System)?

A

NADH releases electrons and Hydrogen ions
FADH releases electrons and Hydrogen ions
These energizes the complexes, which opens hydrogen ion gates
ATP Synthase combines ADP and Phosphorous with Hydrogen ions to form ATP
Creates 36 ATP, CO2, and H2O

17
Q

How does hydrogen cyanide impact oxidative phosphorylation?

A

HCN uncouples oxidative phosphorylation by blocking Cytochrome C oxidase from donating electrons, resulting in inability to create ATP, increases acidosis within cell.

18
Q

How many ATP are created in Aerobic respiration?

A

36 net total ATP

19
Q

What does P stand for in lab values?

A

Partial Pressure

20
Q

What is PO2

A

Partial Pressure of Oxygen in the given environment
Normal: 80-100mmHg

21
Q

What is PaO2?

A

Partial Pressure of Oxygen in the blood
Normal: 80-100mmHg

22
Q

What is PAO2?

A

Partial Pressure of Oxygen in the Alveoli
Normal: 80-100mmHg

23
Q

What is SaO2?

A

The amount of Hgb in the blood that is saturated
Normal: 93-98%

24
Q

What is SpO2?

A

Total Saturation of oxygen bound to Hgb
Normal: 93-98%

25
Q

What is SvO2?

A

Mixed venous oxygen saturation (pulmonary artery catheter)
Normal: 60-80%

26
Q

What is the difference between SpO2 and SaO2?

A
27
Q

What is ScvO2?

A

Central Venous Oxygen Saturation
Central line = 5-8% higher
Normal: 70-80%

28
Q

What is Hgb?

A

Hemoglobin: 12-15 g/dL

29
Q

Q

A

Cardiac Output: 5-6L/min

30
Q

CaO2

A

Total content of oxygen bound to Hgb (16-22ml/O2/dL)

31
Q

DO2

A

Delivery of Oxygen each minute (900-1100ml/kg/min)

32
Q

O2ER

A

Oxygen consumption-Extraction (2ml/kg/min)