Oxidative Phosphorylation Flashcards
What is oxdative phosphorylation?
- Electrons (e-) and proteons (H+) are recycled from reduced coenzymes
- NADH -> E- + H+ + NAD
- FADH -> E- + H+ + FAD
- Electrons flow along an electron transport chain in a series of redox reactions
- Electrons release energy which is used to join ADP + PI -> ATP
- Oxygen is the final electron acceptor - combines with electrons and protons to form water
- Oxidative phosphorylation makes most of ATP in aerboic respiration chemiosmosis in presence of O2 - H20 produced
Why is oxidative phosphorylation important?
The hydrogen atoms carried are important potential important energy storages
The hydrogen atoms carried by coenzymes NAD and FAD
This is a mechanism by which some of the energy of the electrons within the hydrogen atoms is convered in ATP
What is the site of oxidative phosphorylation?
Mitochondria
What is each mitchondria bounded by?
A smooth outer membrane and an inner one that is folded into extensions called cristae
The inner space/matrix of mitochondrion contains proteins , lipids and traces of DNA
Respiration of lipids
Before being respired , lipids are first hydrolosed to glycerol and fatty acids
Glycerol is then phosphorylated and coverted to TP
Fatty acid component is broken down to 2 carbon fragments which is converted to acetly coenzyme A
Oxidation of lipids produce 2-carbon fragments of carbohydrate and many hydrogen atoms are used to produce ATP using oxidative phosphorylation. For this reason , lipids release more than double the enerby for same mass of carbohydrate
Respiration of protein
Protein is another potential source of energy
It is first hydrolsyed into consutient amino aicds
These have their amino acid group removed before entering the respiratory pathway at different proteins deprending on the number of carbon atoms they contain
3-carbon compound coverted to pyruvate while 4- and 5 carbon compound are converted to intermediates to Krebs cyc;e
