Overview of the Cardiovascular System Flashcards
What is the main definition/function of the cardiovascular system?
-The cardiovascular system is defined as the heart, blood vessels and approximately 5 litres of blood.
What are some of the general functions of the CVS?
- Transport of 02 and substrates to cells (e.g. glucose, amino acids, fatty acids)
- Transport of C02 and and metabolites from cells for excretion (e.g. lungs, liver, kidneys)
- Distribution of hormones e.g. adrenaline, insulin,
- Transport of defence mechanisms e.g. immune system,
- Thermoregulation- chemical reactions need correct temperature.
Passive diffusion vs Convection Transport
- Passive diffusion= Random, undirected, thermal movement of molecules.
- Bulk flow using convection Transport is the movement of fluids and solutes down a pressure gradient
- In a resting healthy person Blood flow delivering 02 transport to cells is about 5 litres per minute,
- Failure of heart or pressure gradient (sepsis) prevents bulk flow -No 02 transport to tissue and organs.
The cardiovascular system is a dual circulation, parts are in parallel and in series, what is meant by this?
- In parallel= Cardiac output is ‘split up Safeguard 02 supply, most organs are supplied this way,
- In series= Liver and kidneys receive ‘used’ blood, this can be an issue is CVS is compromised
The Cardiovascular system is a closed system, what is happening at the same time?
- What happens in one part in one part of the CVS has a major impact on the other parts,
- In a resting healthy CVS- this is happening at the same time- keeping balance:
- 5l/min of blood returns to the right side of the heart (Venous circulation),
- 5l/min of blood is ejected by the right side of the heart to the lungs and,
- 5l/min of blood returns to left side of heart (pulmonary circulation)
- 5l/min of blood is ejected by left ventricle to the body (systemic circulation)
What is Venous circulation?
-When blood returns to the right side of the heart,
What is pulmonary circulation?
-When blood returns to the left side of the heart
What is systemic circulation?
-When blood is ejected by left ventricle to the body
What is Heart rate?
-The number of heart beats per minute.
What is stroke volume?
-Volume of blood ejected from heart per beat
What is Cardiac output?
-Volume of blood ejected from heart per min which is the same as Blood flow in Circulation.
What is blood pressure?
-The pressure of circulating blood flow on blood vessel walls,
What is Total peripheral resistance?
-Resistance of blood vessels to blood flow
How do you calculate Cardiac Output?
-Heart Rate X Stroke Volume
How do you calculate Arterial BP?
-Cardiac Output X Total Peripheral Resistance