Overview of Immune System Flashcards
Immunity came from the latin word ___ which denotes what?
> Immunitas
> Denotes protection from legal prosecution
What are the 2 concepts of immunology?
> Traditional concept
> Modern concept
− Protection against infectious diseases (anti-infection)
− Immunity to different types of pathogenic microorganisms.
− 📣 “basic concept for immunity – ward of infections”
Traditional concept
− Study of immune response & function of which an individual recognizes and excludes antigenic foreign substances; consumption, function, and mechanism of immune response and the disease associated with immunity
− 📣 “Also recognizes that different substances, foreign, and self-molecules molecules trigger immune response”
Modern concept
___ is a reaction to microbes and molecules recognized as foreign, regardless of physiologic or pathologic consequences of such reaction.
Immunity
Consists of cells and molecules responsible for immunity
Immune system
This is a collective and coordinated response to the introduction of foreign substances.
Immune response
Immune response elicited by self-molecules.
Autoimmune response
Immune system is a ___ system
FUNCTIONAL SYSTEM (not an organ system)
What does it mean to be immune?
To be protected
Immune system is made up of network of what?
> Cells
> Tissues
> Organs that work together to protect the body
Immune system functions to call for what when there are invaders in the body?
> Help
> Identify
> Tag
> Destroy
> Remember invaders
Organs of the immune system is divided into three groups:
> Primary lymphoid organs
> Secondary lymphoid organs
> Tertiary lymphoid tissues
What are the primary lymphoid organs?
Thymus and bone marrow, where maturation of lymphocytes takes place
What are the secondary lymphoid organs?
> Lymph nodes
> Spleen
> various MALT
> GALT
Type of lymphoid organs that function as a lymphoid organ in which they trap antigen and provide sites for mature lymphocytes to interact with that antigen.
Secondary lymphoid organs
What are the tertiary lymphoid organs?
Most prominent of these are cutaneous associated lymphoid tissues
They can import lymphoid cells during inflammatory response
Tertiary lymphoid tissues
Normally contains fewer lymphoid cells than 2 L.O
Tertiary lymphoid tissues
Natural/Native immunity
Innate Immunity
Early line of defense against microbes
Innate Immunity
Cellular and Biochemical defense that exist BEFORE an infection occurs
Innate Immunity
Capable of RAPID/IMMEDIATE response to invading microbes and injured cells (Mins to hours of exposure)
Innate Immunity
Specific for structures that are common to groups or related microbes 📣 “repeated exposure invoke virtually identical innate response”
Innate Immunity
