Overview of Drug Info Relevance Flashcards
1
Q
How will your knowledge develop after graduation?
A
- new knowledge of diseases will come out
- new drugs, deviced, procedures, dietary supplements
- new studies on old drugs devices, procedures, dietary supplements
2
Q
How is medical knowledge growing?
A
- exponentially faster over time
3
Q
What will be relevant after 10 years?
A
- “What was leanred in the first 3 years of medical shcool will be 6% of what is known at the end of the decade”
- over half the knowledge you leanred will be irrelevant due to new drugs– you will be outmoded if you can’t keep up
4
Q
What are the limitations of book chapters and review articles?
A
- Book chapters (18 months old) and review articles (12 months old) may not contain contemporary data
- authors might have biases
- might not divulge enough info for you to understand the topic
5
Q
When would a book chapter not be sufficient?
A
- when the topic is on your clinical specialty
- when book chapters disagree with eachother
- when you’re doing a formulary review on a pharmacy and therapeutics committee
- when youre worried about being scammed
- interested in researching in the area
- writing your own book chapter
6
Q
What is the P & T Committee?
A
- The formulary is an important way to assure that clinicians have the drugs they need to care for patients without going broke
- Pharmacy and Therapeutics committee
- more physicans than pharmacists
- pharmacist does the review and presents to the rest of the committee
- committee votes to approve of the drug for use and restrictions
7
Q
How will people scam data?
A
- over-exaggerate results or how they fit with the body of the literature
- primary endpoint is not the one originally planned
- supplemental research is not upto personal standard
- products have not been studied for adverse effects
- drug rep does not refute data or weaknesses
8
Q
What do I need to do?
A
- be cautious when reading a study
- determine: internal validity, external validity; and how the study fits into similar studies
- Know quality, strength, and applicability of meta analysis
9
Q
Will I have to generate new data as a pharmacist?
A
- yes, drug use evaluations (DUEs)