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anatomy: ch 19 blood > overview > Flashcards

overview Flashcards

1
Q

what are the contents of the fluid portion of blood

A

plasma
plasma proteins
solutes

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1
Q

what are the 3 functions of blood

A

transport
regulation
protection

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2
Q

name the function of albumins

A

affect osmotic pressure and transports fatty acids

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3
Q

name the function of globulins

A

serve in immune response

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4
Q

name the function of fibrinogen

A

precursor/inactive form of fibrin (a clotting protein)

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5
Q

what are erthrocytes

A

Red blood cells

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6
Q

What are leukocytes

A

White blood cells

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7
Q

What are thrombocytes?

A

platelets

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8
Q

What is hematopoiesis

A

development of formed elements in red blood marrow (RBC, WBC, and platelets)

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9
Q

what is the precursor stem cell of a erythrocyte

A

proerythrocyte

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10
Q

what is the stem cell of granulocytes

A

myleoblast

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11
Q

what is the stem cell of a monocyte (macrophage)

A

monoblast

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12
Q

what is the stem cell of B and T lymphocytes

A

lymphoblast

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13
Q

what is the stem cell of thrombocytes (platelets)

A

megakaryocyte

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14
Q

What hormone aids erthropoiesis

A

erythropoietin

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15
Q

what hormone aids thrombopoiesis

A

thrombopoietin

16
Q

define heme

A

red pigment
contains iron at the center to reversibly bind O2

17
Q

define globin

A

protein that binds CO2

18
Q

explain heme recycling

A

aged RBC are phagocytosed by macrophage in spleen

Hb split into globin and heme

19
Q

What happens to globin during RBC recycling

A

broken down into individual amino acids

20
Q

what happens to heme during RBC recycling

A

the iron is removed from heme.

21
Q

define transferrin and ferritin

A

carrier of iron from blood to liver

Iron storage in liver

22
Q

Explain the fate of heme pigment during recycling

A

Heme > biliverdin (green) > bilirubin (orange) > blood > liver > bile > small intestine > urobiligen > stercobilin

OR

Heme > biliverdin (green) > bilirubin (orange) > blood > liver > bile > small intestine > urobiligen > urobilin > urinr

23
Q

what mechanism is used for RBC formation

A

negative feedback

24
Q

Explain the negative feedback loop of RBC formation

A

low O2 delivery detected by kidneys
increased erythpoietin formation
increased proerythroblast to erythroblast formation in red bone marrow
^RBC = ^O2 delivery = reduction of initial stress

25
Q

Explain the cause and effect of sickle cell anemia

A

amino acid substitution in globin chain

changes shape of RBC

anatomy: ch 19 blood (3 decks)

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