Overview Flashcards

1
Q

what does ecstasy do at the neural level

A

indirect 5ht-2A agonist = increases serotonin
increases oxytocin
increases dopamine

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2
Q

what does alcohol do at the neural level

A

indirect NMDA receptor antagonist
indirect GABA agonist

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3
Q

what does cocaine do at the neural level

A

Blocks the serotonin and dopamine reuptake transporters

indirect agonist

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4
Q

what is the effect of SSRIs

A

indirect serotonin agonist

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5
Q

what is the effect of zoloft

A

dopamine reuptake inhibitor
binds via sigma receptor = myriad a biological processes

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6
Q

what is the effect of paxil

A

noradrenaline reuptake inhibitor
inhibits cytochrome P450 enzymes
muscarinic antagonist

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7
Q

how does MAOis work

A

inhibit the break down of monoamines

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8
Q

how do tricyclics work

A

blocks the noradrenaline and serotonin reuptake pumps

competitive antagonist of post synaptic acetylcholine neurons

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9
Q

how does donepezil work

A

prevents the break down of acetylcholine

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10
Q

how does memantine work

A

non-competitive NMDA antagonist

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