Overnight wear of contact lenses Flashcards
how many patients are found to take naps in their CLs
50%
how many night does:
Continuous wear
Extended wear
Flexible wear
refer up to
Continuous wear refers to up to 30 nights
Extended wear refers to up to 6 nights (a 2 weekly lens goes down to 1 week i.e. the modality/frequency decreases)
Flexible wear: occasional overnight wear
what is the risk of overnight CL wear
the eye is deprived of oxygen and the lens will sit tightly and become dehydrated = complications associated with CL wear
give 4 reasons why people will choose to wear lenses overnight
Convenience
- No cleaning every day
- Less use of solutions reduces cost
- No removing the lens everyday
- Clear vision when waking (for high myopes)
Lifestyle
- Certain occupations
Therapeutic bandage CL
High Rx and aphakes
why is Therapeutic bandage CL used and how is it changed
- eye protection from the wind
- elderly patients
- sensitive corneas
hospital changes the lens every month, px does not change if carer is not there
give 4 reasons why you do not want to fit EW lenses
- Relative to daily wear (DW) there is a significant increase
in the risk of a serious adverse event
e.g. microbial keratitis is more likely to occur due to the build up of deposits on the lens as its not coming out and being cleaned - Hypoxic environment- closed eye, less tear circulation
- Frequent monitoring is required
px has to visit more, every 3 months - Needs to be an ‘ideal’ px
The environment needs to be ideal - hygienic surroundings
The px needs to be very compliant - need to come back for aftercare
The px needs to be vigilant - make px aware there could be infection and signs of them
what 3 qualities should an EW lens have to compensate for the hypoxic environment it creates for the cornea
- make sure fitting is not tight and that they move well
- lens should have good wettability
- make sure of no deposit build up
what was one of the earliest overnight lenses made from, when were they created and up to how long could they be used
- glass haptic lenses
- fitted in the 1880s
- worn continuously for up to 2 years at a time
what lens was created in 1970,
what type of material was this and what was more feasible with this.
when did the use of these lenses increase
- the Permalens (developed by John de Carle from London)
- gas-permeable material
- rigid lenses for EW more feasible
- their use increased gradually in the 1980s
what did the FDA improve in 1981
extended wear hydrogels for cosmetic correction
how many americans were wearing EW lenses by 1985
what concerns were there about EW lenses by the end of the 1980s and what happened as a result
4 million Americans wearing EW lenses
By the end of the 1980s there
were concerns about incidence of microbial keratitis in EW patients. Majority of papers suggested that soft EW was the major concern, but the publicity affected the EW market for all lens types.
what did the poggio and schein study impact
Reported incidence of keratitis was
- 4.1/100,000 in daily CL wearers,
- 20.9/100,000 in Extended Wear patients.
- Other studies supported similar findings
- Confidence lost in EW lenses
as this figure was enough to change the value in the FDA guidance
what did the FDA do in 1989
recommended that EW Hydrogel CL wear should be limited to 6 nights and 7 days. After this px must remove lenses
what did the FDA do in 1999
approved use of SiH lenses for up to 30 days CW
oxygen is not an issue for SiHy lenses, but hoped that microbial keratitis risk was not so bad
which are the most common groups of people to be prescribed CW lenses
older patients and males
list 5 changes that occur in closed eye conditions
- Available oxygen reduces (from 155mmHg to 55mmHg)
- Demand for corneal oxygen increases
- pH changes from 7.45 to 7.25
- Tear osmolarity decreases
- Increased oedema
what is the Holden and Mertz criterion and which lenses did not meet this criteria
minimum Dkt required to prevent central oedema during overnight wear
it is the formula that tells you how much o2 is required by the eyes to prevent central corneal oedema
it has 2 versions: a DW and a EW equation
most hydrogels didn’t meet the criteria
what does oxygen availability to the cornea depend on with the lens
depends on oxygen
permeability (Dk) and the thickness of the lens (t)