Overdose

Question 1

treatment for paracetamol overdose ?

Answer 1

ingested < 1 hour = activated charcoal

N-acetylcysteine

Question 2

treatment for aspirin overdose ?

Answer 2

charcoal

urinary alkalisation with IV bicarbonate

Question 3

treatment for benzodiazepine overdose ?

Answer 3

flumazenil

Question 4

treatment for lithium overdose ?

Answer 4

mild/moderate = IV saline 
severe = haemodialysis, sodium bicarbonate

Question 5

treatment for warfarin overdose ?

Answer 5

vitamin K

prothrombin complex

Question 6

treatment for heparin overdose ?

Answer 6

protamine sulphate

Question 7

treatment for tricyclic antidepressant overdose ?

Answer 7

IV bicarbonate

Question 8

treatment for carbon monoxide overdose ?

Answer 8

100% oxygen

hyperbaric oxygen

Question 9

treatment for lead overdose ?

Answer 9

dimercaprol

calcium edetate

Question 10

treatment for opiate overdose ?

Answer 10

IV or IM naloxone

Question 11

treatment for digoxin overdose ?

Answer 11

digoxin specific antibody fragments i.e. digibind

Question 12

treatment for beta blocker overdose ?

Answer 12

atropine if bradycardia

glucagon if no response to atropine

Question 13

what substance overdose presents with injected conjunctivae, impaired motor coordination, increased appetite, dry mouth, and anxiety?

Answer 13

marijuana

Question 14

what substance overdose presents with dilated pupils, confusion, hypotension, and poor coordination ?

Answer 14

barbiturates i.e. thiopentone, phenobarbital

Question 15

what substance overdose presents with tactile hallucinations, euophoria, grandiosity, hypertension, paranoia, fever, skin excoriations ?

Answer 15

emphetamines
(skine xcoriations with methamphetamines)

Question 16

mechanism of amphetamines

Answer 16

induces reversal of monoamine transporters
increases neurotransmitter release