Overall Flashcards
What is the structure of a PMT in order of when the photons hit it?
Photocathode (which turns it into photoelectrons), then dynodes (amplifies signal) and finally to an anode
What does a focussing grid do in a PMT?
Ensures the electrons are electrons are focussed towards the next dynode
Is there lead shielding at the back of a gamma camera and why?
Yes to ensure the detected gamma rays only come from the patient
What is a collimator in basic terms for nuclear medicine?
A lead plate with thousands of small holes
How big are the holes of a collimator roughly?
A couple of millimetres in diameter (depends on type)
What is the purpose of a collimator in nuclear medicine?
Only gamma rays travelling in the direction of the holes can get through, which provides spatial localisation so an image can be formed
Why is the crystal sealed in an air tight frame?
Because it is hygroscopic, so air and light need to be kept out
What interactions happen in a scintillation crystal?
Photoelectric absorption or Compton scattering
Roughly how many light photons are produces from the scintillation of one gamma photon in a crystal?
Several thousand
What are scintillation crystals usually made of in gamma cameras?
Sodium iodide doped in thallium NaI(Tl)
Why is the inner surface of the encapsulation of a scintillation crystal covered in a diffuse white reflective coating?
The light will be reflected preferentially back out through the back of the camera so that more are collected
What do the photons meet after the scintillation crystal in a gamma camera?
A light guide
What are the three signals produced by the pulse arithmetic in a gamma camera?
Position (x and y) and energy
The light output in the crystal of a gamma camera is proportional to what?
The energy of the gamma ray
How is the position of a gamma ray worked out from a distribution of signal across PMTs (how does anger logic work here)?
The centroid of the distribution is found (colloquially known as centre of gravity)
Why does the position determined by anger logic have uncertainty and what is this known as?
Random fluctuations in the amount of light collected by each PMT and variations in the number of photoelectrons produced at the photocathode. Intrinsic spatial resolution
What is the value of the intrinsic spatial resolution of a gamma camera?
3 - 5 mm (3.5 mm according to lecturer)
What is the energy resolution of a gamma camera?
9% (according to lecturer)
How do you work out the x (and y) position of a gamma ray using anger pulse arithmetic?
Weighted sum of all the voltages (x1V1+x2V2+… where x1 is the position of PMT 1) divided by the sum of all the voltages (total energy)
How is the total energy of a gamma ray calculated using anger pulse arithmetic?
All the voltages summed from all PMTs
What are the advantages of a NaI(Tl) scintillation crystal?
Moderate density (good stopping power for gamma rays), high atomic number (most interactions at 140 keV are photoelectric absorption, good photopeak efficiency), light output proportional to energy absorbed, emits blue light which the crystal is transparent to and well matched to PMTs, can grow large crystals
Roughly how many scintillation photons are produced per keV in a NaI(Tl) crystal?
35 per keV
What is the wavelength and energy of the scintillation photons from a NaI(Tl) crystal?
415 nm (blue light) and 3 eV
How thick are standard crystals in gamma cameras?
3/8th of an inch (9.5 mm) - this is standard or 5/8th of an inch