Ovary

Question 1

If malignant, ovarian tumors are leading cause of death from repro CA.

Answer 1

MOST ARE BENIGN

Question 2

palpable ovarian or adnexal mass in pre-menarchal or post-menopausal patients is suggestive of ovarian neoplasm

Answer 2

:)

Question 3

Risk factors of ovarian cancer

Answer 3

age, low parity, decreased fertility, delayed childbearing, FH
OCPs taken for >5 years decreases risk by %30

Question 4

Genetic risks of ovarian cancer

Answer 4

1st degree relative: %5 risk
BRCA1: %45 risk
BRCA2: %25 risk

Question 5

Frequency sequence of female repro cancer (3)

Answer 5

endometrial > ovarian > cervical

Question 6

Sequence of mortality caused by female repro cancer (3)

Answer 6

Ovarian > endometrial > cervical

Question 7

HX/PE - ovarian cancer

Answer 7

neoplasms usually asymptomatic
mild/ non-specific GI ssx/pelvic pressure
early disease not detected on pelvic exam

Question 8

HX/PE - advanced ovarian CA

Answer 8

%75 present w/ advanced malignant disease

abdominal pain, bloating, palpable mass, ascites

Question 9

DX of ovarian CA

Answer 9

Increased CA-125 associated w/ epithelial cell CA (%90 of ovarian CA)
used as marker of progression or recurrence
Transvaginal U/S 1st step in W/U of symptomatic female

Question 10

Premenopausal increase CA-125 marker

Answer 10

may indicate benign disease like endometriosis

Question 11

Postmenopausal increase CA-125 marker

Answer 11

indicates greater chance that ovarian CA is malignant

Question 12

Ovarian mass TX: pre-menarche

Answer 12

> 2cm needs close f/u and usually surgery

Question 13

Ovarian mass TX: pre-menopause

Answer 13

obs <10cm with benign characteristics

surgically evaluate >10cm if complex or unchg

Question 14

Ovarian mass TX: post-menopause

Answer 14

closely follow with U/S masses w. benign characteristics

surgically evaluate palpable masses

Question 15

Ovarian CA TX

Answer 15

surgery - TAH/BSO, omentectomy, pelvic and peri-aortic lymphadenectomy
post-op chemo routine unless low-grade