Ovary

Question 1

Tumors that can be commonly bilateral

Answer 1

Serous (up to 66%)
Endometrioid (40%)

Question 2

Requirement for transitional cell carcinoma

Answer 2

> 50% malignant transitional epithelium
If <50% = malignant brenner tumor

Question 3

What are the two syndromes associated with fibrothecomas

Answer 3

Meig’s syndrome
Basal cell Nevus syndrome

Question 4

What is the mutation in sertoli-leydig cell tumors

Answer 4

DICER1

Question 5

What is the mutation in granulosa cell tumors?

Answer 5

Fox L2

Question 6

This is a metastatic gastrointestinal carcinoma to the ovaries, characterized by bilateral metastasis, composed of mucin-producing cancer cells with a signet ring appearance most often of gastric origin

Answer 6

Krukenberg tumor

Question 7

Immuno phenotype of STIC

Answer 7

Increased KI 67
p53 mutant

Question 8

What is the most common mutation seen in endometrioid carcinoma arising from an endometriotic cyst?

Answer 8

ARID1A

Question 9

What is the cut off microinvasion size in serious borderline tumor with micro invasion

Answer 9

Less than 5 mm

Question 10

What is the lining of mucinous cystadenoma

Answer 10

Mullerian, gastric foveolar, intestinal type with goblet cells, and sometimes with neuroendocrine and paneth cells

Question 11

What is the lining of MBT and mucinous carcinoma

Answer 11

Gastrointestinal type epithelium

Question 12

This is the ovarian carcinoma, most commonly associated with paraneoplastic hypercalcemia and venous thromboembolism

Answer 12

Clear cell carcinoma

Question 13

SCTAT is associated with what syndrome

Answer 13

Puetz-jegher’s syndrome