Ovarian Hyperstimulation Syndrome

Question 1

What is the cause of ovarian hyperstimulation syndrome?

Answer 1

Fertility medication, benign hamartoma

Question 2

Sx of mild vs moderate vs severe ovarian hyperstimulation syndrome

Answer 2

Mild = bloating

Moderate = weight gain of 2lbs/day

Severe = SOB, pleural effusion

Question 3

What is the cause of tissue edema and hypovolemia in ovarian hyperstimulation syndrome?

Answer 3

Capillary leakage

Question 4

How does tissue edema present in ovarian hyperstimulation syndrome?

Answer 4

Ascites and hydrothorax

Question 5

How is the tissue edema in ovarian hyperstimulation syndrome treated/managed?

Answer 5

IV crystalloid and albumin

Hematocrit and electrolyte monitoring

Possible ascites drainage

Question 6

What are the consequences of hypovolemia in ovarian hyperstimulation syndrome?

Answer 6

Decreased organ perfusion; resulting in liver/renal impairment

Hemoconcentration; can result in VTE

Question 7

How is decreased organ perfusion in ovarian hyperstimulation syndrome treated/managed?

Answer 7

Hematocrit and electrolyte monitoring

Question 8

How is hemoconcentration in ovarian hyperstimulation syndrome treated?

Answer 8

Prophylactic heparin because hemoconcentration has thromboembolic effects