Ovarian Cancer

Question 1

Stage IA

Answer 1

Limited to one ovary or fallopian tube; negative washings, no surface involvement

Question 2

Stage IB

Answer 2

Limited to both ovaries or fallopian tubes; negative washings, no surface involvement

Question 3

Stage

• IC1
• IC2
• IC3

Answer 3

Limited to one or both ovaries WITH

• surgical spill
• capsule rupture or surface involvement
• malignant ascites/washings

Question 4

Stage IIA

Answer 4

Extension/implants on uterus

Question 5

Stage IIB

Answer 5

Extension/implants on other pelvic tissues

Question 6

Stage IIIA2 +/-

Answer 6

Microscopically confirmed extra-pelvic peritoneal mets +/- LNs

Question 7

Stage IIIB

Answer 7

Macroscopic extrapelvic <2 cm +/- LN

Question 8

Stage IIIC

Answer 8

Macroscopic extrapelvic >2 cm +/- LN

Question 9

Stage IVA

Answer 9

Malignant effusions

Question 10

Stage IVB

Answer 10

Mets in liver, spleen, inguinal LNs, bowel invasion

Question 11

BRCA1 risk OV/BR

Answer 11

40% risk of ovarian cancer
60% risk of breast cancer

chromosome 17

Question 12

BRCA2 risk OV/BR

Answer 12

27% risk of ovarian cancer
50% risk of breast cancer

chromosome 13

Question 13

Baseline population risk of ovarian cancer

Answer 13

1.3% (compared to 13% for breast cancer)

Question 14

Types of Epithelial Ovarian Cancer

Answer 14

• Serous
• Endometrioid
• Clear Cell
• Malignant Brenner
• Mucinous
• Mixed