Other Leaukaemia

Question 1

Classic flow for plasmablastic dc

Answer 1

CD 123+, CD 56+, cd4 45 43 +ve
1/3 are TdT +ve
Mpo cCD3 79a and 11c neg

Question 2

BDCA- 2

Answer 2

Highly specific flow marker for blastic plasmacytoid DC neoplasm

Question 3

Flow for megakaryoblastic

Answer 3

Cd41 and or cd61
The more mature marker CD 42 less frequently positive
No lymphoid markers
Mpo CD 34 CD 45 and hla dr often negative

Question 4

Blasts in M7

Answer 4

Cytoplasmic blebs
Deeply basophillic
1-3 nucleoli
Agranular