Other important bits n bobs Flashcards
Conditions/specifics to ask about as a general cover in the history
Heart disease
Stroke
VTE
HTN
Headache/migraine
Epilepsy
Liver disease
Bowel disorders
Diabetes
Cancer
HIV
Smoker?
BMI?
What fhx specifically ask about
breast ca (BRCA carriers - UKMEC 3 for CHC and 2 for others)
VTE (if first deg fam <45 then = UKMEC 3 CHC, if >45 = UKMEC 2)
General history
Remind confidential
Personal history
Family history
PMHx
Social hx incl smoking, alcohol, domestic abuse, alcohol/drugs
Meds hx
Sexual hx
Obstetric hx (thinking about breast feeding)
Gynae hx (incl LMP, regularity, lenth, pain, HMB, endo, fibroids)
Cervical screening
Criteria to be a migraine
2 or more of:
- photophobia
- headache impairs ability to function
- nausea
criteria to be aura
visual aura rating scale (VARS)
Visual aura lasts between 5-60 mins = 3 points
Aura symptom develops gradually over 5-60 mins = 2 points
Presence of dark/ blank spot = 2 points
Presence of zigzag lines = 2 points
Visual impairement affects same side in both eyes (NB usually unilateral) = 1 point
Migraine with aura if >=5 points
Key to establish length of time symptoms last for. If <5 min wont count.
ICHD-3 criteria migraine
A. At least two attacks fulfilling criteria B and C
B. One or more of the following fully reversible aura symptoms:
visual
sensory
speech and/or language
motor
brainstem
retinal
C. At least three of the following six characteristics:
- at least one aura symptom spreads gradually over ≥5 minutes
- two or more aura symptoms occur in succession
- each individual aura symptom lasts 5-60 minutes1
- at least one aura symptom is unilateral
- at least one aura symptom is positive
- the aura is accompanied, or followed within 60 minutes, by headache
D. Not better accounted for by another ICHD-3 diagnosis.
What should a fertility consultation address? [3]
- Advice on how to get pregnant and factors affecting pregnancy
- The time frame involved
- Recommendations for seeking medical advice if pregnancy fails to occur
How many times a week should women be having sex when trying to conceive?
2-3 times a week
Should you recommend timing to fertile period
No it isnt recommended and there is no need for temperature measurements of ovulation testing kits but it’s acknowledged many women will use these so understanding the principles is important
How long before extra fertility tests should be done when a couple is trying?
12 months - after 12mo, 80% of couples will have conceived. If fails after regular sex for a year further assessment and ix of woman and man to be done.
Women under the age of 36 are advised to wait 12 months before getting ix.
What things decrease fertility?
-AGE - massive curve drop off from 31y/o
- Recurrent PID
- Inflammatory bowel disease
Modifiable factors affecting female fertility
- Smoking
- Alcohol
- Drugs
- Taking folic acid
- Normal BMI
- Stress
- Caffeine
- Exercise- can boost fertility by improving insulin resistance and glucose control. Also helps reduce stress.
Changing these can increase chance of conception, and reduce the risk of pregnancy related complications.
Non-modifiable factors affecting female fertility
- PCOS
- Age
- Chronic medical conditions such as diabetes - MDT approach to prep for pregnancy
- PID
- IBD
- Delay due to current contraception (DMPA is the only one)
What are the pregnancy risks related to being overweight?
- Increase miscarriage risk when BMI >30
- Gestational diabetes
- Pre-eclampsia
- Stillbirths
- Baby >4kg
- VTE
What are the peripartum risks related to being overweight?
- Preterm labour
- Long labour
- Shoulder dystocia
- Postpartum haemorrhage
- Operative/instrumental delivery
- Anaesthetic risks
Postpartum risks related to being overweight?
- Infections
- VTE
What preconception advice should be given to women with high BMI
- Weight loss advice
- Increased dose of folic acid (5mg)
- Referral to dietician if BMI >40
- 10mcg vit D following conception
- Advice they might need hospital based antenatal care for raised BMI
- Nutritional advice - no need for extra calories first 2 trimesters, extra 200kcal/day in 3rd trimester, not to diet in pregnancy but to eat healthily
What medical problems need special attention w/r to pregnancy?
- Diabetes
- Epilepsy
- VTE
- Mental health issues
- Renal
- Cardiac
- HTN
- Severe asthma
- AI conditions
- HIV
Consider preconception referral to maternal fetal medicine.
Risks around preg assoc with diabetes
What women should do prior to conception
- poor control is accoc with inc risk of congenital malformation, miscarriage, stillbirth & neonatal death
prior to conceiving:
- pre-preg specialist review, esp if underlying microvascular disease
- optimise diabetic control and reduce their hba1c <48
- eye screening
- women with t2dm may need to switch to insulin
good glycaemic control reduces risks
What women with epilepsy be advised w/r to conception
They need specialist pre-conception counselling to review and ADJUST THEIR AEDS
Meds such as valproate and carbamazepine together with other multidrug regimes = inc risk of congenital malf and LT neurodevelopmental probs
Women on valproate should be on a pregnancy prevention programme
DO NOT STOP MEDS UNTIL SPECIALIST REVIEW. Continue contraception.
What is the leading cause of maternal death in the UK?
VTE!!
What are significant RFs for VTE in pregnancy? If women have any of these RFs what should be done?
- Personal or Fhx
- Thrombophilia
- High BMI
- Increased maternal age
MDT preconception counselling needed involving HAEM AND OBSTETRICS. Some women may need to change anticoag - WARFARIN = TERATOGENIC. Or start prophylactic treatment
What needs to be done around mental health w/r to pre-conception?
- Screen for undiagnosed MH issues
- Pre-existing MH issues may be exacerbated by pregnancy and a new baby. Some psychotropics are teratogenic and need specialist review. e.g. carbamazepine, valproate, lithium, lamotrigine, paroxetine. CONTINUE CONTRACEPTION until review.
Who is usually involved with pregnancy planning for women who have physical or learning disabilities?
Holistic consultation needed
Extensive input usually required from carers, social services and support workers
Who do you refer same sex couples wanting to conceive to?
Fertility specialist and counselling
What is available depends on the region
What psychosexual issues might affect fertility? Approach?
Persistent issues , despite counselling, such as severe vaginismus or erectile dysfunction and who are unable to conceive a child naturally should be referred for fertility treatment
Women wants to conceive but amenorrhoeic / oligo?
early fertility referral should be considered to exclude endocrine dysfunction e.g. PCOS, prolactinoma
Approach to women with cancer / cancer treatment in past of child bearing age
Advise to discuss fertility prospects with a specialist even if preg isnt an imminent issue. Women undergoing cancr treatment can often have discussion with specialist prior to starting and eggs can be collected.
Aside from advice around conceiving, what should ALWAYS be explored and asked about in a fertility consult?
DOMESTIC ABUSE
it is more common during pregnancy and women are more likely to die when pregnant.
Consider involving adult AND child safeguarding.
What are the additional risks to the baby for overweight mothers
- increased risk of fetal abnormalities and neural tube defects
- risk of obesity and diabetes later in life
- neonatal hypoglycaemia
- increased perinatal mortality
What screening tests can be done in the preconception period?
The pre-conception period provides an opportunity to perform relevant screening tests, either to reduce risk of complications during pregnancy e.g undiagnosed STI or to maximise disease prevention, e.g. cervical screening
- Ensure cervical screening up to date. (NB should be avoided when actually pregnant)
- CT screening - untreated genital CT can lead to neonatal pneumonia and conjuctivitis
- Rubella screening - can cause fetal loss or congenital rubella syndrome. If not had, or had less than 2 doses of MMR vaccine, then is to have two doses 1 month apart and then not get pregnant for 1 month after.
- Other STI and BBV screen
- Sickle cell/ thalassaemia screen
- Vit D screen
- Varicella screen
What preconception nutrition and vitamin supplementation advice should be given incl doses, when to take, and who applies to
- Folic acid - reduces neural tube defects eg spina bifida, anencephaly, cleft palate. Foods naturally high in it = brussels, beans, oranges, yeast. Dose: 400mcg OD. Higher dose of 5mg for women who have h/o or fhx neural tube defects, DM/coeliac dis, BMI>30, sickle cell/ thalassaemia, twins, on AEDs ***** or enzyme inducers, partner with spina bifida. Take when trying to conceive and for 12w gestation. No SEs.
- Vitamin D - helps prevent rickets in the child and osteoporosis in the adult. Take 10mcg/day. Particularly recommened in: darker skin, BMI >30, little exposure to sun
- Vitamin C - as it helps iron absorption
What foods should people trying to conceive AVOID
- Any supplement containing vitamin A
- High dose multivitamins
- Fish liver oil supplements
- Unpasteurised cheeses
- Uncooked meats and raw or lightly cooked eggs
- Peanuts
- Certain fish such as swordfish, and restrict tune (mercury poisoning)
- Foods high in fat and sugar
To summarise - what should be discussed in a pre-conception consultation:
- Factors affecting fertility incl modifiable
- STI screening
- Cervical cytology screening
- Supplements - folic acid, vit D, vit C and foods to avoid
- Full PMH and drug hx
- Domestic abuse
- Full history in general
- MH
How long will it take to get an abortion when I want one? What if I need time to think about it?
- assessment within 1 week
- then abortion within 1 week of assessment
- may choose to wait longer however the implications should be explained - risks and complications increase with increasing gestation
I want an abortion - what is my gestation?
- Estimate gestation based on the first day of LMP, provided has regular cycle.
The gestational age is based on the date of the last period, not the date of conception.
So count the weeks from the first day of LMP.
- USS is usually done to confirm gestation prior to abortion
What is considered to be a ‘very early gestation’ for an abortion, what are the issues with abortions at this time and how are these mitigated?
PT may confirm before visibility on USS (appearance of fetus ~5-6w).
Abortions can still be carried out provided that:
1. No sx of ectopic
2. Woman aware of small ectopic risk and f/u appts may be needed
3. 24h emergency contact info provided
What is the gestational limit for most abortions in the UK? What are caveats to this?
23+6. ALL elements of abortion must be completed by then.
Caveats = fetal defects, risk to mothers life
What is used for a medical abortion and how is it done? Latest can have it?
Oral mifepristone 200mg followed by 800mcg misoprostol (buccal, sublingual or vaginal) 24-48h later
10 WEEKS IF AT HOME. If >10w done in hospital. If >10w in hosp, repeated doses of misoprostol til preg passes
What does mifepristone do
Blocks progesterone receptors directly = endometrial degeneration, cervical softening and dilatation, release of endogenous prostaglandins, and an increase in the sensitivity of the myometrium to the contractile effects of prostaglandins.
What does mifepristone do
Blocks progesterone receptors directly = endometrial degeneration, cervical softening and dilatation, release of endogenous prostaglandins, and an increase in the sensitivity of the myometrium to the contractile effects of prostaglandins. Causes embryo to detach from uterine wall.
What does misoprostol do
Misoprostol dilates the cervix and induces muscle contractions which clear the uterus.
Surgical abortion - what happens? talk me through the weeks and how it varies
Cervix is prepared no matter when done
If <14w misoprostol is used to prep the cervix
>14w osmotic dilators are placed into the cervix hours or day before
Then suction tube used to evacuate. Half a day procedure if <19w. If >19w then cervix prepared D1 and procedure done D2
Can be LA/ GA / sedation.
What follow up is needed after abortion?
BASICALLY IF AT HOME - DO A PT AT 2W, OTHERWISE NOTHING
Depends on the abortion
1. Early medical at home: low sensitivity urinary pregnancy test no sooner than 2w after
2. For other medical abortions if done at home then same as above but none needed if visible passage of preg in hospital.
3. Surgical - none needed.
No need for any other types of abortion
What needs to be considered about abortion at home vs hospital
- womens pref
- medical and social factors:
support at home
distance from hospital
age - if under 16 should be in hosp or clinic