Other Flashcards
1
Q
potency
A
how quickly drug enters bloodstream
2
Q
efficacy
A
%response of drug
2
Q
example of a microorganism (souce of drugs)
A
penicillin from fungi
3
Q
why are amide groups a problem in drug structures?
A
not metabolically stable
4
Q
examples of excipients
A
corn starch
gelatin
sucrose
5
Q
corn starch and gelatin as an excipient. Why?
A
binding agents and viscosity increase
6
Q
sucrose as excipient. Why?
A
sweetening agent and viscosity increase
7
Q
bioavailability
A
%drug enters bloodstream
8
Q
Factors that influence drug bioavailability
A
enzyme activity
patient age and genetics
if taken with food
9
Q
hydrogen donors
A
NH, SH, OH, FH
10
Q
hydrogen acceptors
A
lone pairs, =O
11
Q
Is an enzyme good for oxidation?
A
Enzyme P450
12
Q
A