Other Flashcards
1
Q
Cellular targets of antibiotics
A
Cell wall synthesis
Nucleic acid synthesis
Ribosomal protein synthesis
Cell membrane
2
Q
Mechanisms of resistance
A
Altered permeability, eg decrease in channel expression (useful when drug target is in cell) Inactivation/destruction of antibiotic Alteration of binding site New binding sites Efflux pumps Bypass of metabolic pathways