OTC Flashcards
What is Constipation
Decrease in bowel motility due to infrequent stool s or difficulty passings stools
Symptoms of Constipation
Bloated, Abdominal discomfort/distention
Disease induced (Consitipation)
Irritable bowel syndrome, Thyroid dysfunction, Crohn’s disease
Exclusions for self-treatment of Constipation
- Previous appropriate self-care does not resolve symptoms
- Blood in stool
- Vomiting
-Fever - Abdominal pain
- Symptoms persisting >1 week
-Recent Weight loss
MOA of Bulk-forming Laxatives
pull fluid into stool (initial treatment for simple constipation)
3 Drugs of Bulk-forming Laxatives
Methylcellulose(Citrucel), Calcium polycarbophil(Fibercon), Psyllium (Metamucil)
The brand name of Methylcellulose
Citrucel
The brand name of Calcium polycarbophil
Fibercon
The brand name of Psyllium
Metamucil
MOA of Emollient Laxatives
increases the softening of stool (Agents help to prevent constipation by relieving hard, dry stool)
Adverse effects of Emollient Laxatives
Diarrhea, abdominal cramping
Onset action of Emollient Laxatives
24-72 hours
1 drug of Emollient Laxatives
Docusate sodium
The brand name of Docusate sodium
Colace
Dosing of Docusate sodium
Children > 6 years: 100mg PO daily
Adults : Up to 100 mg PO tid
MOA of Lubricant Laxatives
softens and coats for a “slippery stool”
Adverse Effects of Lubricant Laxatives
Abdominal cramping, diarrhea, nausea, vomiting
Onset of action of Lubricant Laxatives
8 hours
1 drug of Lubricant Laxatives
Mineral oil
Dosing of Mineral Oil
Children 6-11 yrs : 10-25mL PO per day
Adults : 15-45 mL PO per day
Recommendation of Mineral Oil
for patients who need to avoid straining
Exceptions of Mineral Oil
- Very young patients
- Advanced age
-Debilitated patients - Not a good recommendation due to lower absorption of fat soluble vitamins
- Caution : sit upright when taking medications due to risk of aspirating mineral oil into lung (liquid pneumonia)
MOA of Hyperosmotic Laxatives
draws water into the colon and provides local irritation to prompt bowel evacuation
Adverse effect of Hyperosmotic Laxatives
stomach discomfort, bloating