osullivan lectures

Question 1

how much of the human geenome is mitochondrial genome

Answer 1

0.0005%

Question 2

what is euchromatn

Answer 2

less tigthly bound dna that is dispersed throughout th enulceus (can be easily expressed

Question 3

what is heterochromatin

Answer 3

tightly condesnesed dna unlikely to be expressed

Question 4

what is faculative heterochromatin

Answer 4

exists in geneteically active or inactive form

Question 5

what is constitutive heterochromatin

Answer 5

always condensed and inactively (largely made of reptitive dna around centromeres)

Question 6

how much dna is on chromosomes

Answer 6

varies (~50Mb on 21 + 22 and >250Mb on 1 + 2)

Question 7

when did human genome project start

Answer 7

1990

Question 8

what were the findings from human genome project

Answer 8

~20,5000 protein coding genes

human genome has significantly more segmental duplications than other mammalian genomes

Question 9

what percentage of genome do coding dna take up

Answer 9

2%

Question 10

how many protein coding genes are there

Answer 10

20,000 (but more proteins bc of spllicing)

Question 11

where is there a high gene denisty of protein coding genes

Answer 11

chromosomes 17/19