Osteoporosis Meds Flashcards
Oh my goodness, is it spring break yet?
I’m over this….okay back to work
Evista: class
Selective estrogen receptor modulator
Evista: MOA
Binds to selective estrogen receptors and decreases bone resorption
Evista: indication
Px and Tx of osteoporosis
Evista: side effect
Hot flashes, peripheral edema
Evista: contraindication
Venous thrombosis
Evista: Dx-Dx
May decrease absorption of thyroid supplements
Do you need to cycle Evista with progestin
No you do not!
Fosamax: class
PO Biphosphenate
Fosamax: MOA
Decreases rate of bone resoprtion
Fosamax: indication
Px/Tx of osteoporosis in women;
Tx of osteoporosis in men;
Tx Paget’s disease
Fosamx: side effects
Esophagitis, hypophosphatemia
Fosamax: contraindications
HypoCa++
Esophageal abnormalities/dysphagia
GFR below 35
Fosamax: Dx-Dx
NSAIDs, antacids
How and when do you take Fosamax?
In the AM with 6-8 oz of water
I just took my Fosamax, and I’m tired. I want to lay down…
But I have to stay upright for at least 30 minutes after taking it.
Reclast: class
IV Bisphosphenate
Reclast: MOA
Inhibits osteoclast activity and skeletal Ca++ release
Reclast: indication
Px/Tx of osteoporosis;
Tx of multiple myeloma, metastatic bone lesions, hyperCa++ of malignancy, Paget’s disease
Reclast: side effects
Atypical Fx, ocular infection, infusion reaction
Reclast: contraindications
GFR below 35
Reclast Dx-Dx
Calcitonin, PPIs, NSAIDs
Osteoporosis isn’t cool. Don’t become osteoporotic.
My calcium window is closed, but you still have time! Save yourself! Eat dark leafy greens!….but not arugula. Arugula is gross.
On second thought, if you eat the arugula, there will be none left for me to eat.
Can I offer you seconds on this delicious arugula salad?
gag
