Osteoporosis&Foot Neuropathy Flashcards
Q: What T-score indicates osteoporosis?
< -2.5
Content: Life choices and bone health (5)
- Adequate Ca intake (~1200 mg/day)
- Optimal Vit D levels
- WB exercise
- Avoid tobacco use
- Avoid excessive alcohol use
Content: Foot Care Education (6)
- Check feet daily
- ALWAYS wear shoes
- No lotion/oil between toes
- Keep nails clipped
- Manage calluses
- Report changes immediately
Diagram: Mechanism of Action of Bisphosphonates - Osteoclasts are targets
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Content: Side Effects of Bisphosphonates (6)
- Upper GI irritation
- Osteonecrosis of the jaw
- Severe musculoskeletal pain
- HypoCa
- Scleritis
- Atypical femur fractures
Content: Foot Examination (3)
- comprehensive foot exam should be completed at LEAST annually
- those with neuropathy should have feet visualized every medical visit
- those with diabetes should check their feet each day
Q: Osteoporosis is a problem of _________ peak bone _____ and _____________ bone _____.
decreased, mass, increased, loss
Q: What does FRAX calculate?
10 year fracture risk, for things like hip fracture and osteoporosis fractures
Content: Secondary Evaluation of Osteoporosis (7)
- Comprehensive metabolic panel
- CBC
- 24 hour urine for Ca, creatinine, Na
- 25-Hydroxy Vit D
- TSH
- SPEP/UPEP if anemic
- PTH
Q: What calcium supplements are available?
- Calcium carbonate
- Calcium citrate
Content: 3 ways to define osteoporosis.
- Microarchitectural deterioration of bone tissue leading to decreased bone mass
- Bone fragility
- Susceptibility to fracture
Content: Four neuropathy deformities (4)
- Prominent metatarsal heads
- Hammer/claw toes
- Hallux Valgus/bunions
- Charcot Foot
T/F: High impact WB exercise increased BMD by 1-2% at the spine and hip.
True
Q: What is the recommendation for exercise to prevent osteoporosis?
30 min, most days of running, walking, or elliptical + muscle stregnthening and balance exercises
Q: What are pharmacologica treatment options for low bone mass? (4)
- Bisphosphonate
- Teriparatide
- Denosumab
- Selective Estrogen Receptor Modulators
Content: Teriparatide (2)
- Anabolic (bone building agent)
- Daily injection
Q: What 3 pulses should you check during a foot exam?
- Posterior tibilais
- Dorsal pedis
- Ankle brachial index (ABI)
Q: _________ involvement in foot neuropathy is __________.
Early, crucial
Content: Calcium carbonate (2)
- Needs stomach acid for absorption
- Taken with meals
Diagram: Vit D formation
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Content: Skin (3)
- Think, shiny, brawny and/or frail
- Dry
- Calluses/wounds
Diagram: Identify the Deformity
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Upper = corn
Lower = callus
Defn: Claw toe
Hyper extension of MTP with PIP/DIP flexion
Q: How do you assess fall risk?
TUG - Timed get up and go
Q: What medications put you at high risk for osteoporosis? (3)
- Steroids
- Aromatase inhibitors
- Androgen deprivation therapy
Q: What are the mortality rates 1 and 5 years after amputation?
40%, 80%
Q: What is FRAX?
Fracture Risk Assessment Tool
Q: When does bone mass begin to decline?
Around 50 yo
Content: Charcot Arthropathy (4)
- Progressive bone destruction and ligament damage leading to arch colllapse and impaired skin integrity
- Affects abot 9% of those with diabetes
- Unclear if etiology is neurotraumatic, neurovascular, or both
- Generally treated with complete immbolizations in a total contact cast with protected WB
Q: How many million individuals in the US are affected by osteoporosis?
10 million
Content: Exercise recommendations for foot neuropathy
At least 30 min most days - consider foot integrity
Content: Vitamin D supplementation (5)
- Vit D2 - ergocalciferol
- Vit D3 - cholecalciferol
- supplementation guided by 250HD value
- Can be taken with or without food
- Safe upper limite = 2,000IU
Content: Assessment - Low Risk Foot Neuropathy (4)
- Preserved sensation
- No defromity
- Intact circulation
4 Tx: Annual foot exam, education, good footwear
T/F: For every standard deviation below the norm, the risk of fractures triples.
False: doubles
Content: Goals of the foot exam (4)
- Est. history/diagnostic factors
- Identify risks
- Intervention
- Education
Content: Assessment - High Risk Foot Neuropathy (6)
- Sensory loss
- Deformity
- Vascular disease
- Callus formation
- Hx of ulcer or amputation
- Tx: comprehensive assessment, education, diabetic shoe
Content: Education (4)
- General diabetes self care
- Foot/skin care
- Daily skin checks
- Proper footwear (breathable, adjustable, wide toe box, good support)
Diagram: Identify the Deformity
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Claw toes
Q: What habit can increase your risk of neuropathy?
smoking (current or past)
Content: Risk factors for Osteoporosis (10 - general idea)
- Genetics
- Low Ca intake
- Low vitamin D stores
- Tobacco and alcohol us
- Prior history of fracture
- Medications
- Malabsorpation
- Excessive urinary calcium
- Overactive thyroid gland
- Other medical conditions
Content: Sensation assessment (2)
- Semmes Weinstein Monofilament (10 locations)
- Vibratory sensation (128 Hz tuning fork, latency > 10 sec = sensory loss)
Diagram: Identify the Deformity
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Hammer toe
Content: Types of Bisphosphonates (4)
- Alendronate -wkly
- Risedronate - wkly/moly
- Ibandronate - moly/IV every 3 mo
- Zolendronic Acid - IV annually
T/F: Neuropathy is implicated in 25% of non-traumatic amputations.
False, 50-75%
Content: Toenails (3)
- Thickened
- Deformed
- Ingrown
Content: Primary Osteoporosis (2)
- unrelated to chronic illness
- Related to aging and decreased gonadal function
Q: What is HbA1c?
Average blood sugar over a peroid of 3 months
Defn: Hammer toe
Hyperextension of MTP and DIP
Content: glycemic control recommendations for foot neuropathy
HbA1c goal of < 6.5-7
Q: When does bone mass peak?
Between 20-25 yo
Q: What type of training increased spine BMD?
Resistance
Content: Causes of neuropathy (6)
- Diabetes
- Tumor, trauma
- Autoimmune disease
- Vitamin B, E, niacin deficiency
- Exposure to toxins
- Infection
Content: OE for foot neuropathy (5)
- Condition of skin, hair, toenails
- Deformities
- Pulses
- Sensation
- Shoe wear
Diagram: Identify the Deformity
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Hallux Valgus
Content: Nutrition recommendations for foot neuropathy (4)
- Montior BMI - stable or weight loss
- Fresh fruits/veggies
- Pre meal glucose 90-130 mg/dl
- Post meal glucose 180 mg/dl
Q: What imaging is often used to identify osteoporosis?
DEXA
Q: For bone health how often should bone density be evaluated?
On treatment = every 1-2 years
Not on treatment = every 2 years
Defn: Z-score
number of standard deviations from age matched mean density
Content: TUG (5)
- Stand from a seated position
- Walk ~10 ft
- Turn around
- Return to seated position in chair
- Normal time < 10 seconds
Content: Offloading (5)
- Total contact casts (change ever 1-2 wks)
- Orthotics/walking boots
- Surgical shoes
- Dressings
- Cutouts
Q: How should you elevate a pts. heels?
With pillow under calves
Content: SE for foot neuropathy (7)
- Contributing diagnosis
- PMH/social factors
- Medications
- Complications
- Hx of LE surgery, ulcer, amputation
- Current or past smoker
- HbA1c (diabetes)
Content: Ulcer intervention (4)
- Debulk callus
- Control moisture
- Decrease infection risk
- Edema management
T/F: WB activities decrease BMD.
False
Q: What T-score indicated osteopenia?
-1 to -2.5
Q: What is BMD?
Body mass density - comes from a DEXA test
Q: How much Ca is in 8 oz of milk?
300 mg
Cotent: ABI Scale (6 parts)
> 1.2 = vessels are incompressible, consider toe brachial indexes
- 0-1.2 = normal
- 9-0.99 = acceptable
< 0.9 = arterial disease
0.5-0.8 = intermittent claudication
< 0.5 = severe arterial disease
Defn: T-score
number of standard deviations from the young adult mean density
Content: Hair
May be present or absent
T/F: FRAX is the treatment decision making tool in previously treated pts.
False, untreated
T/F: Menstraul cycle effects gains in BMD.
True
Q: When does the z-score apply for osteoporosis?
pre-menopausal females and males < 50
Content: Calcium citrate
Can be taken with or without food
Content: Calcium supplements (2)
- Limit to ~500 mg in a dose
- May cause constipation
Q: Who will be referred to PT for osteoporosis type treatment?
Those at increased risk or fall, unstable gait, weakness
Q: What % of those with diabetes will develop neuropathy?
50%
Q: What type of training increased hip BMD?
high impact
Content: Secondary osteoporosis (2)
- Secondary to chronic illnesses/meds that cause accelerated bone loss
- Ex. glucocorticoid use, hyperthyroidism
Content: 4 types of neuropathy
- Peripheral - UE/LE
- Autonomic - CVS, temp reg, bowel/bladder
- Proximal - thigh, hip, core mm
- Focal - sudden loss in one n. or group of n.
Q: Who could you refer pts. with foot neuropathy to? (4)
- Podiatry
- Wound care
- Nurse educator
- Dietician
Content: Denosumab (3)
- Inhibits osteoclast function
- Decreases bone resorption
- Consider in pts. with kidney dysfunction