Osteoporosis Flashcards
1
Q
What is the prevalence of osteoporotic fractures?
A
1 in 3 women over 50
1 in 5 men
2
Q
What is the definition of osteopenia?
A
T score -1 to -2.5
3
Q
What is the definition of osteoporosis?
A
T score -2.5 or lower
4
Q
What is the Z score?
A
Compares BMD with age, sex and weight matched controls
5
Q
At which site is there increased fracture risk in obesity?
A
Upper arm
6
Q
What initial investigations should be ordered if Z score < -2?
A
FBE UEC CMP LFTs vitamin D PTH TSH ESR CRP SPEP serum FLC urine bence jones testosterone
7
Q
What further investigations might be considered in investigating for osteoporosis?
A
Coeliac serology if suspect malabsorption E2 LH FSH if suspect premature menopause Hypercotisolism screen 24 hour urine calcium and creatinine Bone turnover markers (CTX)
8
Q
When should osteoporosis treatment be considered based on FRAX?
A
If 10 year risk of osteoporotic fracture is >20% at any site or >3% at hip
