Osteoporosis Flashcards

1
Q
A
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2
Q

Define osteoporosis.

A

It is a metabolic bone disease characterised by low bone mineral density and and increased risk of fractures.

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3
Q

What is the prevalence of osteoporosis in 1. females over 50yrs and 2. males over 50yrs.

A

1 in 3 women
1 in 5 men

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4
Q

Describe the pathophysiology of osteoporosis.

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5
Q

Classify and list the causes of osteoporosis.

A
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6
Q

list some RFs for osteoporosis.

A
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7
Q

What are the common symptoms/ complaints at presenting history of osteoporosis?

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8
Q

What are the common signs of osteoporosis?

A
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9
Q

What are some ddx for osteoporosis?

A
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10
Q

DEXA SCAN - differentiate between the T and Z score.

A
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11
Q

Describe is the key diagnostic investigation for osteoporosis? Outline the possible result interpretations.

A
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12
Q

What supportive blood investigations can be done to determine the etiology of the osteoporosis?

A
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13
Q

What blood results would point you to a dx of osteomalacia?

A
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14
Q

How would you calculate the risk of fractures in a patient with osteoporosis?

A

mostly hip, sometimes lumbar spine

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15
Q

What are all your investigations for osteoporosis?

A
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16
Q

What is the acute and lifestyle management of osteoporosis?

A
17
Q

What is the indication for pharmacological management of osteoporosis?

A
18
Q

List the common medications used to treat osteoporosis?

A
  1. Oral bisphosphonates
  2. IV bisphosphonates
  3. Denosumab
  4. Raloxifene
  5. Teriparatide
19
Q

What is the MOA, dosage and SEs of the following:
1. Oral bisphosphonates

A
20
Q

What is the MOA, dosage Xand SEs of the following:
1. IV bisphosphonates

A
21
Q

What is the MOA, dosage and SEs of the following:
1. Denosumab

A
22
Q

What is the MOA, dosage and SEs of the following:
1. Raloxifene

A
23
Q

What is the MOA, dosage and SEs of the following:
1. Teriparatide

A
24
Q

Outline the general management of any fracture.

A