Osteoporosis Flashcards
Define osteoporosis.
It is a metabolic bone disease characterised by low bone mineral density and and increased risk of fractures.
What is the prevalence of osteoporosis in 1. females over 50yrs and 2. males over 50yrs.
1 in 3 women
1 in 5 men
Describe the pathophysiology of osteoporosis.
Classify and list the causes of osteoporosis.
list some RFs for osteoporosis.
What are the common symptoms/ complaints at presenting history of osteoporosis?
What are the common signs of osteoporosis?
What are some ddx for osteoporosis?
DEXA SCAN - differentiate between the T and Z score.
Describe is the key diagnostic investigation for osteoporosis? Outline the possible result interpretations.
What supportive blood investigations can be done to determine the etiology of the osteoporosis?
What blood results would point you to a dx of osteomalacia?
What about mineral bone disease?
How would you calculate the risk of fractures in a patient with osteoporosis?
mostly hip, sometimes lumbar spine
What are all your investigations for osteoporosis?
What is the acute and lifestyle management of osteoporosis?
What is the indication for pharmacological management of osteoporosis?
List the common medications used to treat osteoporosis?
- Oral bisphosphonates
- IV bisphosphonates
- Denosumab
- Raloxifene
- Teriparatide
What is the MOA, dosage frequency and SEs of the following:
1. Oral bisphosphonates
What is the MOA, dosage Xand SEs of the following:
1. IV bisphosphonates
What is the MOA, dosage and SEs of the following:
1. Denosumab
What is the MOA, dosage and SEs of the following:
1. Raloxifene
What is the MOA, dosage and SEs of the following:
1. Teriparatide
Outline the general management of any fracture.
