Osteomyelitis

Question 1

For hematogenous infection, what are common pathogens and empiric treatment for Neonates

Answer 1

• -> Strep, Staph, Gm (-)

- -> Treatment: Vancomyin/Cloxacillin + 3rd gen ceph. Depends on if MRSA suspicious

Question 2

what are common pathogens and empiric treatment for Children?

Answer 2

Staph, Strep, rarely gm (-)

Treatment: Cloxacillin/Vancomycin. Add on cefotaxime if not immunized to H. flu

Question 3

what are common pathogens and empiric treatment for Adults?

Answer 3

• Strep and gm (-)

- -> Treatment: Cloxacillin or cefazolin.

Question 4

Contiguous (infection of bone adjacent to site of entry/trauma)
Head/Neck pathogens and treatment

Answer 4

• -> Anaerobes, Strep, Staph, gm (-)

- -> treatment: Clindamycin (i.e. gets gm (+) b/c can target MRSA and anearobes) + gentamicin

Question 5

 Spread from soft tissue:

Answer 5

o Usually strep or staph

o Use cloxacillin or cefazolin.

Question 6

 Spread from genitourinary system:

.

Answer 6

o Usually gm –ve

o Ciprofloxacin, 3rd generation cephalosporin