Osteomalacia, Rickets, Paget's Disease of Bone

Question 1

How is Osteomalacia and Rickets alike and different?

Answer 1

• both involve abnormal mineralization of bones

- Rickets occurs before the epiphyseal plates close and Osteomalacia occurs after the epiphyseal plates close

Question 2

What causes Osteomalacia/Rickets?

Answer 2

-Vit D deficiency

Question 3

How does one get a Vit D deficiency?

Answer 3

• low sun exposure
• Nutritional
• Malabsorption
  
  • Billbroth type II gastrectomy
  • Jejunoileal bypass
  • Sprue
  • chronic renal failure

Question 4

A 43 yo presents with pelvis pain, muscle weakness, and low serum Ca. X-Ray shows Milkman’s lines and Looser zones, along with decreased bone density. What is the likely Dx?

Answer 4

• Osteomalacia

- if this were a kid the Dx would be Ricket’s

Question 5

How would you Tx a patient with Osteomalacia or Rickets?

Answer 5

• Ergocalciferol as a Vit D supplement
• Phosphate supplement
• Calcium supplement