Osteoarthritis/ Rheumatoid Arthritis Flashcards
What is the generic name of Tylenol?
a. naproxen
b. ibuprofen
c. indomethacin
d. acetaminophen
d. acetaminophen
What is the generic name of Motrin?
a. naproxen
b. meloxicam
c. ibuprofen
d. nabumetone
C. Ibuprofen
Select all that apply. What is the brand name of naproxen?
a. nabumetone
b. Naprosyn
c. Anaprox
d. Aleve
e. feldene
B, C, D
What is the generic name of Indocin?
a. celecoxib
b. indomethacin
c. diclofenac
d. sulfasalazine
b. indomethacin
What is the generic name of Mobic?
a. indomethacin
b. Piroxicam
c. meloxicam
d. diclofenac
C. Meloxicam
What is the generic name of Feldene?
a. Indomethacin
b. Meloxicam
c. Celecoxib
d. none of the above
d. none of the above, generic name is piroxicam
What is the generic name of celebrex?
a. celexa
b. celecoxib
c. certolizumab
d. citalopram
b. celocoxib
What is the generic name of voltaren?
a. methotrexate
b. leflunomide
c. ibuprofen
d. diclofenac
d. diclofenac
What is the brand name of Nabumetone?
a. Rheumatrex
b. Rituxan
c. Rituximab
d. Relafen
d. Relafen
Rheumatrex=methotrexate
Rituxan=Rituximab
What is the brand name of Methotrexate?
a. arava
b. azulfidine
c. rheumatrex
d. rituxan
c. rheumatrex
arava= leflunomide
azulfidine=sulfasalazine
rituxan= rituximab
What is the brand name of Arava?
a. hydroxychloroquine
b. infliximab
c. etarnecept
d. leflunomide
d. leflunnomide
hydroxychloroquine=plaquenil
infliximab=Remicade
etarnecept=Enbrel
What is the generic name of Plaquenil?
a. nabumetone
b. leflunomide
c. hydroxychloroquine
d. certolizumab
c. hydroxychloroquine
nabumetone=relafen
leflunomide=arava
certolizumab= cimzia
what is the generic name of azulfidine?
a. sulfasalazine
b. azathioprine
c. cyclophosphamide
d. simponi
a. sulfasalazine
azathioprine=imuran
cyclophosphamide=cytoxan
simponi=golimumab
what is the generic name of enbrel?
a. leflunomide
b. etanercept
c. anakinra
d. none of the above
b. etarnercept
leflunomide=arava
anakinra=kineret
what is the generic name of remicade?
a. adalimumab
b. certolizumab
c. golimumab
d. infliximab
d. infliximab
What is the brand name of adalimumab?
a. xeljanz
b. cytoxan
c. remicade
d. humira
d. Humira
What is the generic name cimza?
a. golimumab
b. certolizumab
c. adalimumab
d. infliximab
b. certolizumab
What is the brand name of tocilizumab?
a. simponi
b. humira
c. actemra
d. kineret
c. actemra
what is the brand name of golimumab?
a. cimzia
b. simponi
c. orencia
d. rituxan
b. simponi
What is the generic name Kineret?
a. actemra
b. adalimumab
c. anakinra
d. orencia
C. anakinra
What is the generic name of Orencia?
a. azathioprine
b. adalimumab
c. abatacept
d. cyclophosphamide
c. abatacept
What is the generic name of rituxan?
a. rituximab
b. azathioprine
c. tocilizumab
d. tofacitinib
a. rituximab
Select All that Apply. Which of the following medications are immunosuppressants?
a. tofacitinib
b. azathioprine
c. cyclosphosphamide
d. anakinra
b,c
What is the brand name of Tofacitinib?
a. rituxan
b. simponi
c. xeljanz
d. imuran
c. xeljanz
What is the brand name of azathioprine?
a. voltaren
b. mobic
c. imuran
d. orencia
c. imuran
what is the generic name of cytoxan?
a. azathioprine
b. adalimumab
c. cyclosphosphamide
d. abatacept
c. cyclophosphamide
Which of the following is not an Biologic DMARD?
a. cytoxan
b. abatacept
c. golimumab
d. etanercept
a. cytoxan
What is the dosage strength per capsule in the tylenol thats in the picture?
a. 325mg
b. 500mg
c. 650mg
d. 1 gram
C. 650mg
What is the dose recommendation for Tylenol Arthritis Pain?
a. 2 capsules every 4-6 hours
b. 2 capsules every 6 hours
c. 2 capsules every 8 hours
d. 1 capsule every 8 hours
C. 2 capsules every 8 hours
What is the dosage strength of Tylenol Extra Strength?
a. 325mg
b. 500mg
c. 650mg
d. 1 gram
b. 500mg
What is the dose recommedation for Tylenol Extra Strength?
a. 2 capsules every 4-6 hours
b. 2 capsules every 6 hours
c. 2 capsules every 8 hours
d. 1 capsule every 4-6 hours
b. 2 capsules every 6 hours
What is the dosage strength of Tylenol Regular Strength?
a. 325mg
b. 500mg
C. 650mg
d. 100mg
What is the dose recommendation for Tylenol Regular Strength?
a. 1 capsule q4-6h
b. 2 capsules q4-6h
c. 2 capsules q6h
d. 2 capsules q8h
b. 2 capsulses q4-6 hours
Barakeisha is 35 yo AA women coming to your pharmacy complaining of joint pain. Upon questioning her you find that she complains of joint stiffness in her knees that lasts for about 25 min after waking up or after moving around. Which of the following is the best choice for Barakeisha?
a. ibuprofen 3200mg TID
b. methotrexate 2.5mg PO daily
c. acetaminophen 650mg PO q6h
d. acetaminophen 1gm PO q6h
c. acetaminophen 650mg PO q6h
ibuprofen is for moderate to severe pain
Methotrexate is for Rheumatoid Arthritis
acetaminophen 1gm POq6h is the wrong frequency; it should be 1gm PO TID
Javante is a 56 yo AA comes to the pharmacy and tells you his doctor diagnosed with mild osteroarthris. Upon questioning him you find that he has stable liver disease because he be drinking all the time. What is the best recommendation?
a. acetaminophen 650mg PO q4-6h
b. acetaminophen 1g PO TID
c. acetaminophen 650mg PO q6h
d. ibuprofen 3200mg PO q4-6h
C. acetaminophen <2g/day
For patients with stable liver disease should be taking < 2g/ day of acetaminophen
Lupita is a 46 yo hispanic women that came to your pharmacy 4 weeks ago complaining of joint pain. what is the recommended treatment options for OA patients who have failed acetaminophen?
a. non-selective NSAIDs used at analgesic doses, if the patient is not at high risk for GI bleeding
b. Non-selective NSAIDs with an H2 antagonist to prevent GI bleeding in the high risk patient
c. COX-2 selective inhibitors with sucralfate in the high risk patient
d. COX-2- selective inhibitors with misoprostol in the high risk patient
e. none of the above
a. non-selective NSAIDs used at analgesic doses, if the patient is not at high risk for GI bleeding
What is the common dose of Voltaren?
a. 800-1200mg/day in divided doses
b. 100-150mg/day in divided doses
c. 25mg BID
d. 10mg q4-6h
b. 100-150mg/ day in divided doses
a is the common dose for etodolac
c is the common dose for indocin
d is the common dose for ketorolac
What is the common dose for indomethacin SR?
a. 10mg q4-6h
b. 25mg BID
c. 75mg Daily
d. 100mg/day
c. 75mg Daily
Anita is an underweight 65 yo woman that likes to run and smoke sometimes at the same time. What are her risk factors for developing osteoarthritis?
a. smoking
b. participation in running
c. being underweight
d. advanced age
e. B and D
E. B and D
What are the Adverse Effects of NSAIDS?
Think NSAID…
N Nephrotoxicity
S Stroke
A Acute MI
I Intestinal
D Disorientation
Select All That Apply. What are the most common adverse effects of Arava?
a. HTN
b. skin rash
c. Nausea/ Diarrhea
d. alopecia
e. increased AST/ALD
B,C,D
Which of the following drugs has a half-life of 11 days?
a. sulfasalazine
b. methotrexate
c. leuflunomide
d. plaquenil
c. leuflunomide (ARAVA)
Which medication causes ocular side effects such as impaired accomodation, corneal deposits, blurry vision, scotomas, or night vision?
a. methotrexate
b. rituximab
c. hydroxychloroquinone
d. sulfasalazine
c. hydroxychloroquinone
What is the half-life of plaquenil?
a. 11 days
b. 11 hours
c. 40 days
d. 40 hours
e. 4 hours
c. 40 days
Which of the following medications does not block TNF-alpha?
a. cimzia
b. simponi
c. acterma
d. humira
c. actemra
it blocks IL-6 receptor
Select all that Apply. Which of the following medications blocks TNF-alpha?
a. Enbrel
b. Cimzia
c. kineret
d. actemra
e. Orencia
f. rituxan
g. simponi
h. remicade
i. humira
a,b, g,h, I
Remember CAGE-I are the generic names of the medications that block TNF-alpha
C Certolizumab (cimzia)
A adalimumab (humira)
G Golimumab (simponi)
E Etanercept (enebrel)
-
I Infliximab (remicade)
Which medication blocks IL-1 receptor?
a. actemra
b. kineret
c. orencia
d. rituxan
b. kineret
What is the mechanism of action of rituxan?
a. blocks IL-1 receptor
b. blocks TNF-alpha
c. binds to CD80/ CD86 receptor on APCs
d. binds to CD20 on B cells
d. binds to CD20 on B cells
Which medication can be administered both IV and SUBQ?
a etarcept
b. golimumab
c. abatacept
d. rituximab
c. abatacept
Select All that apply. Which medications can be administed via IV Infusion?
a. etanercept
b. infliximab
c. rituximab
d. tocilizumab
e. certolizumab
B,C, D
Select all that apply. Which medications are administered via SC route?
a. etanercept
b. infliximab
c. adallimumab
d. golimumab
e. certolizumab
f. anakinra
g. tocilizumab
h. abatacept
i. rituximab
A,C,D,E,F,H
Adverse reactions to tocilizumab include all of the following except:
a. infusion-related reactions
b. elevated liver functions
c. multiple sclerosis-like illness
d. elevated plasma lipids
C. multiple sclerosis-like illness
Deoshenique is trying to get pregnant but since she was diagnosed with RA she was put on leuflomide. What would you recommend Deoshenique take to eliminate the arava rapidly from the body?
a. cholestyramine
b. sevelamer
c. hydrochlorothiazide
d. activated charcoal
ABCD is a 36 yo female who was diagnosed with RA 2 years ago. Today she returns to the clinic with active RA with swollen joints after 6 months of methotrexate monotherapy. A decision is made to dc the methotrexate and initiate enbrel. Which of the following needs to be completed before starting Enbrel?
a. TB skin test, assess liver and kidney function, discuss costs
b. TB Skin test, pregnancy test, admnister needed attenuated vaccines
c. pregnancy test, heart failure screening, asses liver function
d. TB skin test, assess for infections, admnister needed live vaccines
D
Which of the following biologic response modifiers reduces activity of IL-6?
a. etanercept
b. tocilizumab
c. abatacept
d. anakinra
d. tocilizumab
