Osteoarthritis Flashcards
What is osteoarthritis?
Condition characterised by the progressive. loss of articular cartilage and remodelling of the underlying bone, usually due to wear
Leading cause of disability in the Western World
Why is osteoarthritis on the increase?
Ageing population
Increasing rates of obesity
What is the most mobile type of joint?
Synovial joint
What type of cartilage is found at a synovial joint?
Hyaline cartilage
What is hyaline cartilage composed of?
Type II collagen
What is the role of synovial fluid?
Reduces friction during movement
Why would joints wear more quickly?
Obesity
Increase in physical activity: high impact
Trauma: that fractures bone gives you rough surface
Loss of cartilage: Less absorption of shock
What are the main features of type I collagen?
bONE
Found in fibrocartilage meniscus
What are the main features of type II collagen?
Cartilage
Describe the pathogenesis of osteoarthritis?
Wear process and secondary inflammation
Progressive loss of articular cartilage and remodelling of underlying bone
Due to the response
……………….
What are the primary causes of osteoarthritis?
Female: advancing age and manual labour
What are the signs of symptoms of osteoarthritis?
Gradual onset
Joint pain
Stiffness
Worsen at the end of day and with activity
What are the signs of symptoms of osteoarthritis?
Gradual onset Joint pain Stiffness Worsen at the end of day and with activity Relieved by rest Deformity
What is varus deformity?
Excessive inward angulation
Knee towards the midline
What is a valgus deformity?
Excessive outward anugaltion
Knee away from midline