Osteoarthritis Flashcards

1
Q

What is the pathogenesis of OA?

A

imbalance between wear and repair of cartilage within joints

may be considerable amount of associated inflammation - periodic flaring

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2
Q

What is it called when there is no causative factor for OA?

A

primary OA

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3
Q

Genetic & Environmental factors that can precipitate OA

A

Genetic: familial link, no mendelian inheritance, no formal genetic mutation identified
Environment: hobbies, type of work, joints with malalignment (development/ pathological)

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4
Q

Secondary OA causes

A
congenital dislocation of the hip
Perthes
SUFE
Previous intra-articular fracture
Extra-articular fracture with malunion
Osteochondral/hyaline cartilage injury
Crystal arthropathy
Inflammatory Arthritis
Meniscal tears
Genu varum / valgum
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5
Q

Signs & Symptoms of OA

A

Symptom: pain
Sign: baker’s cyst

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6
Q

choice of investigation for OA & what it shows

A
X-Ray (LOSS):
Loss of joint space
Osteophytes
Sclerosis
Subchondral cysts
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7
Q

Management of OA

A

analgesia & physiotherapy
(weight loss & exercise)
sometimes - surgery
treat the patient NOT the images!

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