Osteoarthritis Flashcards

1
Q

what is osteoarthritis

A

Osteoarthritis (OA) is a degenerative joint disorder; prevalence increases with age- cartilage destruction exceeds repair

very sudden, insidious onset of joint pain and stiffness

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2
Q

what joints does osteoarthritis affect the most

A

weight bearing, large joints such as the knee, hip and lumbar spine

can also occur in the distal and proximal interphalageal joints of the hands

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3
Q

summarise the pathogenesis of osteoarthritis

A

Synovial joint cartilage destruction

Eventually, there is loss of joint volume due to altered chondrocyte activity

Patchy chronic synovial inflammation and fibrotic thickening of joint capsules

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4
Q

what can cause secondary osteoarthritis

A

Developmental abnormalities (e.g. hip dysplasia)

Trauma (e.g. previous fractures)

Inflammatory (e.g. rheumatoid arthritis, gout, septic arthritis)

Metabolic (e.g. haemochromatosis, acromegaly)

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5
Q

what are some risk factors for developing osteoarthritis

A

obesity and repetitive trauma to joints

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6
Q

what is the difference between osteoarthritis and inflammatory diseases

A

in osteoarthritis; pain worse with movement, worse at the end of the day and not much morning stiffness

inflammatory diseases; pain improves with movement, worse in the mornings and morning stiffness is prolonged

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7
Q

what are some presenting symptoms of osteoarthritis

A

joint pain and discomfort,

stiffness during rest,

difficulty with certain movements,

feelings of instability,

restriction walking, climbing stairs and doing manual tasks

systemic features are usually absent

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8
Q

signs on physical examination

A

local joint tenderness,

bony swellings along joint margins (HEBERDENS NODES AND BOUCHARDS NODES)

pain during joint movement, joint effusion and restriction of RoM

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9
Q

where are heberdens nodes found

A

distal interphalangeal joint

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10
Q

where are bouchards nodes found

A

proximal interphalangeal joint

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11
Q

what investigation will be done

A

X-ray of affected joint/ joints

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12
Q

what will be the x-ray features

A

X-ray findings mneumonic for osteoarthritis

LOSS

Loss of joint space
Osteophytes
Subchrondral cysts
Subarticular sclerosis

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13
Q

what 3 categories can you split management into

A

conservative, medical and surgical

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14
Q

conservative management of osteoarthritis

A

Weight loss and aerobic exercise are effective at reducing pain and maintaining joint function. Weight bearing exercise should be avoided however as it can accelerate the progression of the disease.

Physiotherapy and occupational therapy input help to improve a patient’s gait, mobility and independence, and walking aids may be useful.

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15
Q

pharmacological treatment of osteoarthritis

A

analgesia (NSAIDs)

intra-articular steroid injections in more severe cases

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16
Q

surgical treatment

A

joint replacement (arthroplasty)