OSR CHAP 1 SPINE Flashcards
What two changes occur in the vascular supply to the disk with aging?
Vessels begin disappearing after the age of 10 & Endplates ossify
What is the source of nutrients to the disk?
Diffusion through endplates
What two external factors decrease endplate permeability?
- Smoking; 2. Vibration
What factors increase permeability?
Exercise
How does aging affect the disk’s collagen content?
Decreased collagen content
How does aging affect the disk’s fibril diameter?
Increased fibril diameter and variability
How does aging affect the disk’s noncollagenous protein?
Increased noncollagenous protein
How does aging affect the disk’s pH?
Decreased pH
Magnetic resonance imaging (MRI): what are the rates of false-positive (asymptomatic) findings for patients 40 years old, and >60 years old?
- 40 years old: 60%; 3. >60 years old: 90%
What is the function of the anterior column and the posterior column?
- Anterior column: support; 2. Posterior column: tension band
An anteriorly placed graft is loaded in which two directions and unloaded in which two directions?
- Loaded in compression, flexion; 2. Unloaded in extension, traction
What effect does an anterior plate have on the axis of rotation?
Moves axis of rotation anteriorly
… on the graft in extension?
Loads graft in extension
… on the graft in flexion?
Unloads graft in flexion
What is the definition of terminal bending?
Moments at ends of a long construct
How can terminal bending be prevented?
With intermediate fixation points
How much lumbar torsional resistance is provided by facets, disk, and ligaments?
- Facets: 40%; 2. Disk: 40%; 3. Ligaments: 20%
After a flexion-distraction injury, what is the status of the anterior longitudinal ligament (ALL) and the posterior longitudinal ligament (PLL disrupted)?
- ALL intact; 2. PLL out
Which approach is biomechanically superior in this situation?
Posteriorly based fusions are superior to anteriorly based fusions
How are the cervical spine facets oriented in the sagittal plane?
Cervical: 45 degrees in the sagittal plane
Compare with thoracic and lumbar facet orientation.
- Thoracic: vertical in sagittal plane (essentially in the coronal plane); 2. Lumbar: sagittally aligned
The sinuvertebral nerve originates from which structure?
Sympathetic chain
What structures and elements does it supply?
- Supplies structures within the spinal canal; 2. Supplies posterior elements
What other neurologic structure also innervates the posterior elements?
Primary dorsal ramus also contributes to innervation
Pattern of innervation example: the L3 nerve root innervates which facets?
L3 innervates the L3-4 facets
At which level is the pedicle diameter the smallest?
T5
What is the furcal nerve? What is its clinical significance?
- Peripheral nerve often originating from L4 nerve root; 2. Can result in variable L4 dermatomal distribution
Infection versus malignancy: which generally destroys the disk?
- Infection destroys the disk early; 2. Malignancy usually skips the disk
Compare with the effect of tuberculosis on the disk.
Tb skips the disk early, but may involve the disk late
What are the earliest plain radiographic findings of infection?
Disk space narrowing at 7 to 10 days
What is the natural history of disk space infection?
Spontaneous arthrodesis
What are the two usual treatment for osteomyelitis?
Intravenous antibiotics Brace
What are the three operative indications?
- Failure of conservative treatment; 2. Progressive neurologic deficit; 3. Instability (e.g., fracture)
What are the two negative prognostic factors for infection?
- Increased age; 2. More cephalad involvement
What is the MRI appearance of malignancy on T1 and T2 sequences?
- T1: low; 2. T2: high
What three tumors classically involve the posterior elements?
- ABC (aneurysmal bone cyst); 2. Osteoid osteoma/osteoblastoma; 3. Osteochondroma
Cervical spondylosis is most common at which two levels?
- C5–6; 2. C6–7
Degenerative cervical spondylolisthesis is most common at which two levels?
- C3–4; 2. C4–5
What are the most common levels of cervical trauma in the young?
C4 to C7
What are the most common levels of cervical trauma in the elderly?
C1, C2
What is Spurling’s test? What is its clinical significance?
- Rotation, lateral bend, vertical compression of neck; 2. To identify cervical radiculopathy
What arm position classically relieves the symptoms of cervical radiculopathy?
Symptoms improve with the arm overhead
What is the ideal therapy regimen for radiculopathy? What percentage of patients improve?
Isometric exercises 75% improve
What is the finger escape test? What is its clinical significance?
- Spontaneous small finger abduction secondary to weak intrinsics; 2. Indicative of myelopathy
In what two ways does cervical myelopathy generally progress?
- Long quiescent periods; 2. Stepwise deterioration
What is Lhermittes sign?
Lightning sensation in arms with neck flexion
What does the C4 nerve root innervate?
Scapular muscles
What three roots correspond to reflexes within the upper extremities?
- C5: biceps; 2. C6: brachioradialis; 3. C7: triceps
What is the significance of a hypoactive brachioradialis (BR) reflex?
Hypoactive BR reflex = lower motor neuron involvement (radiculopathy)
What is the significance of an inverted radial reflex (IRR)?
- IRR: hypoactive BR reflex + concurrent finger flexion; 2. Upper motor neuron involvement (myelopathy)
What is Power’s ratio used for? What is its critical value?
- Anterior atlanto-occipital (AO) dissociation; 2. BC/AO >1: abnormal
What is the definition of Torg’s ratio? What is its clinical significance?
- Canal width divided by vertebral body width; 2. For the identification of congenital stenosis
Compare normal and critical values of Torg’s ratio?
- Normal is 1.0; 2. Critical value is <0.8
What three arteries contribute to the spinal cord blood supply?
- Anterior spinal artery (two thirds from vertebral artery); 2. Two dorsal spinal arteries (one third from posterior inferior cerebellar artery [PICA])
The watershed area of the cervical spinal cord is at which levels?
C5 to C7
What are the two classic symptoms of calcified disk disease in a child?
- Neck pain; 2. Torticollis
What is the treatment of choice?
Observation
What is the prognosis?
Likely to go on to spontaneous resolution
What is the most common reason for a missed cervical spine injury?
Inadequate visualization of involved levels
At which two levels are injuries most often missed?
- Cervicothoracic junction; 2. Atlantooccipital junction
In an awake, alert patient without neck symptoms, what is required for C-spine clearance?
- Clinical exam only; 2. No films required
Compare with a patient with neck pain or neurologic deficits.
Three views of cervical spine with or without computed tomography (CT)
What is the normal atlantodens interval (ADI) in adults and in children?
- Adults: <4.0 mm
What are the normal and unstable values of a lateral mass overhang on an open mouth view? What is its clinical significance?
- Normal = 0 mm overhang; 2. Unstable = >6.9 mm; 3. Relevant for Jefferson fracture
What are the two White/Panjabi instability criteria for subaxial C-spine on flexion-extension films?
- Sagittal translation >3.5 mm or 20%; 2. Sagittal rotation >20 degrees
… on resting films?
- Sagittal translation >3.5 mm or 20%; 2. Relative sagittal angulation >11 degrees
On a pediatric lateral C-spine film, what is the normal C2 retropharyngeal space? Retrotracheal space?
- <14 mm retrotracheal
What level is most commonly involved in pseudosubluxation? What is its significance?
- C2 on C3; 2. May be a normal finding in children
What is the key radiographic landmark when evaluating for pseudosubluxation?
Check spinolaminar line
What percentage of space is occupied by the cord? What makes up the remainder?
- 33% cord; 2. 33% dens; 3. 33% empty (cerebrospinal fluid [CSF], fat); Steele’s rule of thirds
What percentage of head rotation occurs at C1–2?
0.5
The arterial arcade around the odontoid process is supplied by which two vessels?
- Vertebral artery; 2. External carotid artery
What are the anterior landmarks for levels C3, C4, C5, and C6?
- C3: hyoid; 2. C4, C5: thyroid
The carotid tubercle is at which level?
C6
What is the C7-T1 landmark?
Sternal notch
With an anterior cervical discectomy and fusion (ACDF), what is the first muscle encountered? What is the innervation?
- Platysma; 2. Facial nerve (cranial nerve [CN] VII)
With an ACDF, the interval for dissection lies between what two anatomical areas?
- Carotid sheath; 2. Trachea
What are the four contents of the carotid sheath?
- Internal carotid artery (ICA); 2. Common carotid artery (CCA); 3. Internal jugular vein (IJV); 4. CN X vagus
What artery lies at the proximal extent of exposure? What is to be done with it?
- Superior thyroid artery; 2. It may be sacrificed
Where is the omohyoid muscle encountered? How should it be retracted?
- Encountered on the medial side of the carotid sheath within pretracheal tissue; 2. Retract medially, may divide if necessary
What are the origin, insertion, innervation, and function of the omohyoid muscle?
- Origin: scapula; 2. Insertion: hyoid bone; 3. Innervation: ansa cervicalis (C1 to C3); 4. Function: depress hyoid bone and larynx
More proximal approaches put which nerve at risk? What is its clinical significance?
- Superior laryngeal nerve; 2. Responsible for high note phonation
Classically, there is increased recurrent laryngeal nerve risk with which approach? Why?
- Right-sided approach; 2. More variable on right (left goes around the aortic arch)
In which interval does the recurrent laryngeal nerve ascend?
Tracheoesophageal interval
What do recent data indicate about the side of approach and recurrent laryngeal nerve injury rate?
Right- and left-sided approaches have equivalent injury rates
What approach places the thoracic duct at risk? What is the treatment if the duct is injured?
- Left-sided approach; 2. If injured, ligate proximally and distally
Horner’s syndrome is a risk at which level? Why?
- C7-T1; 2. Because of the inferior cervical ganglion
Vocal cord paralysis may also occur by which other mechanism? How can this be prevented?
- Compression of larynx between retractor and endotracheal (ET) tube; 2. Prevention: deflate ET tube after retractors are placed, allow tube to re-centralize
What does “SLAC Line” refer to?
The five capital letters in the acronym refer to the following structures (anterior to posterior):; 1. Sympathetic chain; 2. Longus coli; 3. Artery (vertebral); 4. cervical nerve root; 5. Lateral mass
What is the preferred proximal cervical approach for a singer?
Anterior retropharyngeal approach
What is the key posterior triangle for the posterior approach?
Suboccipital triangle
What two structures does this triangle contain?
- Vertebral artery; 2. C1 nerve
What is the most superficial structure?
Greater occipital nerve (C2)
What is the size of the safe zone relative to the C1 spinous process?
1.5 to 2 cm lateral from C1 spinous process to vertebral artery
With a posterior approach, which way should the nerve root be retracted?
Elevate root superiorly
What nerve root is at the highest risk for traction injury? Why?
- C5 at highest risk; 2. Straightest take-off
What is the best way to approach ossification of the posterior longitudinal ligament (OPLL)? What is the preferred surgical technique for decompression?
- Posterior; 2. Laminoplasty
What preoperative sagittal plane requirement is necessary for laminoplasty success?
Cervical lordosis
What is the principal complication of laminoplasty?
Decreased cervical range of motion (ROM) by 50 to 62%
The lateral mass includes which two structures?
- Pedicle; 2. Ipsilateral lamina
For a one-level ACDF, compare outcomes associated with allograft versus autograft use.
Equivalent outcomes
What two clinical conditions are the exceptions?
- Multiple levels; 2. Smokers
In performing a multiple-level ACDF, what should one consider preoperatively?
- Strut graft; 2. Plate; 3. Adjunct posterior fusion
For smokers, is allograft or autograft preferred for one level? What about for two levels?
- One level: always autograft; 2. Two levels: autograft strut
A posterior approach should generally be included with anterior surgeries in excess of ________.
Two corpectomies
What are reported ACDF pseudarthrosis rates for one level?
0.12
What are reported ACDF pseudarthrosis rates for multiple levels?
0.3
What is the significance of the Hillibrand study?
25% of ACDF patients required an additional procedure within 10 years for adjacent-level disease
What is the principal factor in determining adjacent-level degeneration?
Preoperative adjacent-level status
What is the treatment if the lateral femoral cutaneous nerve (LFCN) is cut with graft harvest?
Allow it to retract into the pelvis
What percentage of patients develop long-term pain at the graft site?
0.25
For the elderly patient, is an ACDF or a posterior approach generally better tolerated?
Posterior approach
Increased risk of dysphagia and respiratory compromise occur with which four factors?
- Increased number of levels; 2. Increased operative time; 3. Increased blood loss; 4. More proximal level of surgery
What complication is unique to an posterior approach?
Air embolism
When performing a multilevel posterior laminectomy, what else should one do? Why?
- Instrumented fusion; 2. To prevent postoperative kyphosis
What is the order of relative frequency of the three rheumatoid-related disorders within the cervical spine?
- 1: C1–2 instability; 2. 2: basilar invagination; 3. 3: subaxial subluxation
What are the criteria for atlantoaxial instability in the adult and in the child?
- Adult: >3 mm motion; 2. Child: >4 mm motion
What is the significance if >7 mm motion is seen at C1–2?
- Alar ligaments also disrupted; 2. Contraindication to elective orthopaedic surgery
A posterior atlanto-dens interval (PADI) smaller than ________ is an indication for surgery.
14 mm
What are the expected surgical outcomes if PADI is 10 to 14 mm or <10 mm?
- 10 to 14 mm: can expect neurologic improvement postoperatively; 2. <10 mm: stabilize; improvement unlikely
What is the critical PADI value in flexed position?
Surgery indicated if <6 mm in flexion
What are the two additional operative indications at C1–2?
- > 10 mm motion; 2. Myelopathy
What four surgical options are appropriate if C1–2 subluxation is reducible?
- Gallie technique; 2. Brooks technique; 3. Transarticular screws; 4. Harms technique
What three surgical options are appropriate if subluxation is irreducible? What is the key step to all three?
- Posterior decompression with occiput-C2 fusion; 2. Posterior decompression with C1–2 transarticular screws; 3. Harms technique; Key step with all interventions: decompression!
What is the expected long-term consequence without surgery for instability?
On average, patients die within 8 years
What are the three criteria that indicate that surgery is less likely to be successful? What is the Ranawat category?
- Objective weakness; 2. Upper motor neuron (UMN) signs; 3. Nonambulatory
Upon which two factors is the Nurick classification of myelopathy based?
- Gait; 2. Ambulatory function
What anatomic line lies at the base of the foramen magnum? What is its clinical significance?
- McRae’s line across the base of the foramen magnum; 2. Odontoid should always be below this line (if not, then invagination is present)
What is the most important operative indication for invagination?
Neurologic compromise
… Migration in excess of?
> 5 mm
… Cervicomedullary angle (CMA)?
<135 degrees
… Ranawat measurement?
<13 mm
… McRae’s line?
Odontoid proximal to McRae’s line
What two surgical options are appropriate for basilar invagination?
- Occiput to C2 fusion; 2. Transoral odontoid resection
What are the only two current indications for a transoral approach?
- Cranial nerve deficits (brainstem compromise); 2. Solid posterior C1–2 fusion with persistent anterior cord compromise
What are the two classic symptoms of atlantoaxial arthritis? What is the treatment?
- Headache; 2. Rotational pain; 3. Treatment: posterior C1–2 fusion
What are the criteria for instability: (________ mm, ________ degrees)?
- > 3.5 mm or 20% translation; 2. >11 degrees (static film); 3. >20 degrees (flexion-extension films)
Which gender is most commonly affected? What are the other three primary risk factors?
- Male; 2. History steroid use; 3. RF+; 4. Nodules
An increased risk of neurologic compromise exists with what two radiographic criteria?
- Subluxation >4 mm; 2. Cervical height index >2
What is the treatment of choice?
Posterior fusion and wiring
Where is the skull thickest?
External occipital protuberance
What structures are at risk with screws?
Venous sinuses
What is the Gallie technique?
Spinous process wiring with midline graft
How much relative resistance does the Gallie provide versus flexion, extension, and rotation?
- Good versus flexion; 2. Not good versus extension and rotation; 3. Not good versus extension and rotation
Gallie should not be used in what situation?
Posteriorly displaced odontoid fracture
What is the Brooks technique?
Posterior wiring with bilateral grafts
How much relative resistance does the Brooks provide versus flexion, extension, and rotation?
- Good versus flexion; 2. Better versus extension and rotation; 3. Better versus extension and rotation
With either the Gallie or Brooks, what must be applied postoperatively?
Halo vest
How effective are C1–2 transarticular screws against flexion, extension, and rotation?
Best versus flex, extension, and rotation
How can the vertebral artery be injured with a transarticular screw?
Screw too caudally directed
How can the occiput-C1 joint be injured?
Screw too cephalad
How can the hypoglossal nerve (CN XII) be injured?
Screw too long: too anterior to lateral mass
What are the two functions of the hypoglossal nerve?
- Innervates muscles of tongue; 2. Contributes to strap muscle innervation via ansa cervicalis; 3. Contributes to strap muscle innervation via ansa cervicalis
If considering transarticular screws, which study must be obtained preoperatively?
Preoperative thin-cut CT scan
What percentage of patients have anatomy that precludes C1–2 screws?
0.15
If an iatrogenic injury to one vertebral artery occurs, what is the next step?
Sublaminar wires and graft (Gallie/ Brooks type)
Vertebral artery injury may be seen in association with trauma at what location?
Facet joint injury
How can it be injured intraoperatively?
Lateral bone removal with burr
If a vertebral artery stroke occurs, what is the name of the resultant syndrome? What are its four features?
- Wallenberg syndrome; 2. Nystagmus; 3. Diplopia; 4. Dysphagia; 5. Pain, temperature loss
What is the path of the vertebral artery? Above C1?
- C6 foramen transversarium to C1; 2. Up and medially through arcuate foramen above C1; 3. Up and medially through arcuate foramen above C1
Thoracic disk disease is most common at which levels?
T8 to T12 (especially T11-T12)
What is the classic mechanism of injury resulting in thoracic disk herniation (herniated nucleus pulposus [HNP])?
Torsion + bend
An HNP is most likely to be symptomatic in what two situations?
- Scheuermann’s disease; 2. Calcified disk; 3. Calcified disk
What are the two indications for surgery?
- Myelopathy; 2. Pain with magnetic resonance (MR) correlation; 3. Pain with magnetic resonance (MR) correlation
What is the disadvantage of a posterior approach?
Decreased midline access from the posterior
For the approach, should the surgeon go over or under the rib? From right or left? Why?
- Over rib; 2. From right; 3. Avoid artery of Adamkiewicz
Where is the watershed area for the thoracic spinal cord?
Middle T-spine
Where does the spinal cord end?
L1–2
What are the radiographic criteria for a diagnosis of disseminated idiopathic skeletal hyperostosis (DISH, diffuse idiopathic skeletal hyperostosis)?
Nonmarginal syndesmophytes >3 levels
Is the disk generally involved?
DISH generally spares the disk
What type of syndesmophytes are seen with ankylosing spondylitis?
Marginal syndesmophytes
Are compression fractures more common in the thoracic or lumbar spines? Why?
Thoracic spine more common because it is kyphotic
A vacuum sign on x-ray implies what two characteristics of the fracture?
- Osteonecrosis; 2. Nonhealing; 3. Nonhealing
How can compression fracture acuity be best evaluated?
Short tau inversion recovery (STIR) MRI
What are the five risk factors (in descending significance) for a vertebral compression fracture?
- Prior compression fractures; 2. Decreased bone mineral density (BMD); 3. Family history; 4. Premature menopause; 5. Smoking
On standing lateral films, where should the C7 plumb line fall?
Through the sacrum or within 2 cm anterior to the sacrum
What are the five common causes of kyphotic sagittal imbalance?
- Scheuermann’s disease; 2. Ankylosing spondylitis; 3. Neurofibromatosis; 4. Traumatic (e.g., compression, burst fractures); 5. Iatrogenic (e.g., postlaminectomy, Harrington distraction instrumentation)
What is an SPO? What is the effect on the posterior, middle, and anterior columns?
- Resection of posterior column between the facet joints; 2. Posterior column shortened; 3. Middle column = hinge; 4. Anterior column lengthened
How much correction can be obtained, on average, per level?
10 degrees
What additional procedure may potentially be necessary?
Anterior grafting if a gap opens in anterior disk space
What is a PSO? What is the effect on the posterior, middle, and anterior columns?
- Wedge-shaped resection with apex anterior of vertebral body, pedicle, and posterior elements; 2. Posterior column shortened; 3. Middle column shortened; 4. Anterior column = hinge
How much correction can be obtained, on average, per level? Which levels are preferred?
- 30 degrees; 2. L2, L3 probably safest; 3. L2, L3 probably safest
In thoracolumbar compression fractures, what is the indication for surgery? Why?
Fractures at >3 consecutive levels Increased risk of kyphosis
What are the five surgical indications?
- Unstable injury (posterior ligamentous complex disrupted); 2. >50% height loss; 3. >50% canal compromise; 4. >30 degrees kyphosis; 5. Incomplete or progressive neurologic deficit
If a neurologic deficit is present, what is the preferred surgical approach?
Anteriorly to decompress, fuse
If posterior column involvement is present, what is the preferred surgical approach? What is the significance of a lamina fracture?
- Posteriorly to fuse; 2. Lamina fracture may entrap and compress nerve roots (go posterior)
What is the most common long-term complication of a thoracolumbar burst fracture?
Pain
Compare the reported outcomes of operative versus nonoperative treatment of stable burst fractures.
Equivalent outcomes
What four factors are prognostic for future back pain?
- History of back pain; 2. Smoker; 3. >30 years old; 4. Workmen’s compensation case
In acute low back pain, when do 50% of patients recover? When do 90% of patients recover?
- 50% recover at 1 week; 2. 90% recover at 3 months