OSPE - Drug target Flashcards

1
Q

Salbutamol

A

Beta-2 receptors

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2
Q

Nifedipine

A

Alpha-1 subunits of voltage gated calcium channels (in vessels)

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3
Q

Enalapril

A

Angiotensin converting enzyme (ACE)

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4
Q

Simvastatin

A

HMG-CoA reductase enzyme inhibitor

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5
Q

Aspirin

A

COX enzyme inhibitor

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6
Q

Fluoxetine

A

Serotonin reuptake pump

5HT monoamine transporter

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7
Q

Metoprolol

A

Beta-1 adrenergic receptors

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8
Q

Imatinib

A

bcr-abl tyrosine kinase

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9
Q

Fentanyl

A

MOP mu opoid receptor

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10
Q

Rituximab

A

CD20

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11
Q

Diazepam

A

GABAa receptor

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12
Q

Sildenafil

A

specific phosphodiesterase 5 (PDE5) inhibitor

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13
Q

Clopidogrel

A

P2Y 12 ADP receptors on platelets

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14
Q

Ranitidine

A

Histamine H2-receptor inhibitor

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15
Q

Vancomycin

A

amino acids in the peptidoglycan bacterial cell wall (acyl-D-ala-D-ala)

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16
Q

Metformin

A

AMP activated protein kinase (AMPK)

17
Q

Furosemide

A

Luminal Na2+ K+ and Cl2- co-transporter

18
Q

Prednisolone

A

Glucocorticoid receptors