Osmosis Flashcards
aquaporins
family of membrane proteins forming channels through which water can diffuse
type and number differ in different membranes -> permeability
aquaporins in the kidney
epithelial cells contain numerous aquaporins that can be increased or decreased in number depending on the water balance at the time
osmosis
net diffusion of water across a membrane
addition of solute to water
decreases the concentration of water to less than pure water
concentration of water in pure water
55.5M
factors affecting the degree to which water concentration is decreased by addition of a solute
number of particles of solute in solution
not on chemical nature of solute
ionising molecules in solution
decreases water concentration in proportion to the number of ions formed
osmolarity
total solute concentration of a solution
osmol
1 mol of solute particles
osmolarity and water concentration
the higher the osmolarity, the lower the water concentration
membrane permeable to water but impermeable to solute
same concentration of water and solute will be reached at equilibrium as before
change in volumes of the compartments
semipermeable membrane
membrane permeable to water but impermeable to solute
osmotic pressure
pressure that must be applied to the solution to prevent net flow of water into it
osmolarity and osmotic pressure
greater the osmolarity, the greater the osmotic pressure
nonpenetrating solutes
substances that cannot cross the plasma membrane - don’t penetrate through the lipid bilayer
examples of nonpenetrating solutes
Na+ and Cl- outside the cell, and K+ and other organic solutes inside the cell
osmolarity of ECF
285 - 300 mOsm
osmolarities at equilibrium
ECF and ICF are equal
changes in osmolarity of ECF
can cause cells to shrink or swell as water moves in/out
isotonic
solutions of nonpenetrating solutes having an osmolarity of 300 mOsm - cell neither shrinks nor expands
same concentration of nonpenetrating solutes as normal ECF
hypotonic
solutions have a nonpenetrating solute concentration lower than that in cells - cell swells due to water moving into it by osmosis
hypertonic
solutions with a nonpenetrating solute concentration greater than cells - cell shrinks as water moves out of it into lower water conc area
tonicity
determined by concentration of nonpenetrating solutes in solution
not total osmolarity or penetrating solutes
isoosmotic
solution containing 300 mOsmol/L of solute, regardless of its composition of penetrating and nonpenetrating solutes