OSCE Prep Flashcards
Gastrointestinal System Exam: Inspection
Causes of abdominal distension
Fat Fluid (ascites) Flatus Faeces Fetus Filthy big mass
Gastrointestinal System Exam: Palpation
DDx for Hepatomegaly (INCHIB)
Infection (Hepatitis, EBV, Malaria, Abscess)
Neoplastic (Myeloproliferative disease, HCC, metastasis)
Congestion (Venous) (RHF, TR, Budd-Chari Syndrome)
Haematological (Lymphoma/leukemia, Sickle cell or haemolytic anaemia)
Infiltrate (Sarcoidosis, Amyloidosis, fatty liver)
Biliary (PBC, PSC)
Gastrointestinal System Exam: Palpation
DDx for Splenomegaly
Massive (Malaria, Myeloproliferative disease [myelofibrosis or CML]
Moderate (Lymphoma, leukemia, Portal hypertension, haemolytic anaemia)
Mild (Glandular fever, Rheumatoid arthritis [Felty Syndrome], Infective endocarditis, Pernicious anaemia)
SLE
Gastrointestinal System Exam: Palpation
DDx for Hepato-splenomegaly
Hepatitis, EBV, Malaria, Lymphoma, Leukemia, Myelofibrosis, Sickle cell, haemolytic anaemia, sarcoidosis, amyloidosis
Gastrointestinal System Exam: Hands
DDx for clubbing (gastro causes)
Cirrhosis
IBD
GI lymphoma
Coeliac Disease
Cardiovascular System Exam: Hands
DDx of peripheral cyanosis
Peripheral vascular disease
Raynaud’s Syndrome
Heart failure
Shock
Cardiovascular System Exam: Mouth
DDx of central cyanosis
Hypoxic lung disease
Right-to-left shunt
Methaemoglobinaemia (drug or toxin induced)
Cardiovascular System Exam: Peripheral
DDx of irregular irregular pulse
Atrial Fibrillation
Atrial Flutter
Ventricular ectopic beats
Complete heart block with ventricular escape
To differentiate between AF and VEB without an ECG, exercise the patient, this will abolish VEBs but AF will remain.
Cardiovascular System Exam: Irregular Irregular Pulse
Causes of AF
Ischemic Heart disease Rheumatic Heart disease Thyrotoxicosis Pneumonia/PE/ Alcohol Idiopathic Fever
Cardiovascular System Exam: Heart Failure
Causes of Heart Failure
Pump Failure: IHD, Cardiomyopathy, Constrictive pericarditis, arrythmia or negative inotropes/chronotropes)
Excessive preload: MR or AR, Fluid excess (renal failure or IV fluids))
Excessive afterload (AS or hypertension)
Isolated RHF (Cor Pulmonale secondary to chronic lung disease or pulmonary hypertension (primary/due to MS))
High output cardiac failure (anaemia, pregnancy, metabolic)
Cardiovascular System Exam: Infective Endocarditis
List the stigmata of infective endocarditis
Changing heart murmur Clubbing Splinter haemorrhages Mild Splenomegaly Microscopic haematuria Oslers nodes Janeway lesions Roths spots (retina)
Peripheral Vascular Exam: Critical Limb Ischemia
6 signs of critical limb ischemia
Pain Pallor Pulseless Paraesthesia Perishingly cold Paralysed
Peripheral Vascular Exam: Venous
Causes of chronic venous insufficiency
Valvular incompetance of deep veins (90%)
Obstruction of deep veins (10%)
Peripheral Vascular Exam
Causes of acute limb ischaemia
Thrombosis
Emboli (80% cardiac source eg AF, 10% non-cardiac source eg AAA or peripheral aneurysm, and 10 % unknown source)
Graft rejection/occlusion
Trauma
Peripheral Vascular Exam: ABPI
How is a ABPI done and what do the results show?
Performed using a pencil doppler machine and a standard blood pressure cuff. Bilateral brachial systolic pressures are recorded and then the highest reading is taken as the denominator for both legs.
In legs, take highest systolic reading from DP and PT to use as the numerator
>1.3 = Unreliable - vessels are calcified, commonly seen in diabetics
0.9-1.8 = Normal range
<0.8 = Evidence of peripheral arterial disease (claudication)
<0.5 = significant peripheral arterial disease - gangrene and ulceration
Cardiovascular System Exam: Murmur
Etiology of Aortic Stenosis
Rheumatic Heart disease
Calcified bicuspid aortic valve (50-60)
Calcified tricuspid aortic valve (70+)
Supravalvular stenosis
Cardiovascular System Exam: Murmur
Presentation of Symptomatic Aortic Stenosis
Dyspnoea/Decreased exercise tolerance
Syncope/dizziness
Angina pectoris
Cardiovascular System Exam: Murmur
Physical exam findings associated with Aortic Stenosis
What may you see on an ECG?
Low volume, slow rising pulse
Narrow pulse pressure
Ejection systolic murmur heard loudest over right 2nd intercostal space, radiating to carotids.
LVH with strain pattern, p mitralle, Left axis deviation
Cardiovascular System Exam: Murmur
DDx of Aortic Stenosis
Aortic Sclerosis
HOCM
Pulmonary stenosis (usually congenital)
Mitral regurgitation
Cardiovascular System Exam: Murmur
Etiology of Aortic Regurgitation
Acute: Endocarditis, Aortic dissection, Cusp rupture (congenital, traumatic), Iatrogenic
Chronic: Rheumatic heart disease, aortic root dilatation, congenital bicuspid aortic valve and calcific valve disease
Cardiovascular System Exam: Murmur
Presentation of Aortic Regurgitation
Often asymptomatic
May develop exertional dysnpnoea, angina and symptoms of Heart failure
Palpitations
Cardiovascular System Exam: Murmur
Physical exam findings associated with Aortic Regurgitation
What might you see on CXR
Quincke’s Sign: Pulsatile nailbeds
Corrigan’s Sign: Exaggerated carotid pulse
Wide pulse pressure.
Early diastolic murmur heard loudest over left sternal edge, increased on leaning forward and expiration
CXR: Cardiomegaly, CHF (ABCD)
Cardiovascular System Exam: Murmur
DDx of Aortic Regurgitation
Pulmonary regurgitation Graham Steel (PR secondary to pulmonary hypertension)
Cardiovascular System Exam: Murmur
Etiology of mitral regurgitation
IE, RHD, Calcification, mitral valve prolapse, ruptured chordae tendinae, papillary muscle rupture, connective tissue disorders (marfan’s)
Functional: LV dilation
Cardiovascular System Exam: Murmur
Presentation of Mitral Regurgitation
SOB/Fatigue Other LVF (orthopnea/PND)
Cardiovascular System Exam: Murmur
Physical exam findings associated with Mitral Regurgitation
Pansystolic murmur hear loudest in the mitral area.
AF common
Cardiovascular System Exam: Murmur
DDx of Mitral Regurgitation
Ventricular septal defect
Tricuspid regurgitation
AS
Cardiovascular System Exam: Murmur
For Mitral Regurgitation, what may you see on ECG and CXR
ECG: AF common, VEB’s
CXR: Cardiomegaly or CHF
Cardiovascular System Exam: Murmur
Etiology of mitral stenosis
RHD (99%)
Cardiovascular System Exam: Murmur
Presentation of Mitral stenosis
Dyspnoea Pulmonary oedema/haemoptysis AF RHF (late) Really enlarged atria can compress recurrent laryngeal nerve - hoarseness
Cardiovascular System Exam: Murmur
Physical exam findings associated with Mitral stenosis
Mitral facies
Signs of RHF
AF
Mid-diastolic murmur loudest on LHS with expiration
Cardiovascular System Exam: Murmur
For Mitral stenosis, what may you see on ECG and CXR
ECG: AF or P mitrale (bifid P waves)
Cardiovascular System Exam: Murmur
DDx of Mitral stenosis
Austin Flint (2ndary AR) Carey Coombs (Rheumatic Fever) Tricuspid Stenosis (RHD)
Gastrointestinal System Exam: Inspection
- Causes of Leukonychia
- Causes of Koilonychia
- Causes of xanthomata
- Hypoalbumininaemia
- Iron-deficiency anaemia
- Hyperlipidaemai
Gastrointestinal System Exam: Inspection
Causes of depuytren’s contracture
CLD, diabetes, heavy labour, phenytoin, trauma, familial
Gastrointestinal System Exam: Inspection
Causes of Palmar erythema
CLD, pregnancy, hyperthyroidism, rheumatoid arthritis
Gastrointestinal System Exam: Inspection
Why would someone have increased bruising?
CLD: THrombocytopenia , decreased clotting factors and falls
Jaundice: Biliary obstruction > reduced fat absorption > reduced absorption of fat soluble vitakne (A D E K) - reduced vitamin K means less synthesis of factors 10, 2 7 and 9.
Gastrointestinal System Exam: Inspection
Why would someone have a cushingnoid appearance of the face?
Alcoholic pseudocushings - hypercortisolaemia secondary to stress of repeated alcohol withdrawal
Respiratory Exam: Causes of wheeze
Asthma, COPD, Bronchiectasis, Fixed bronchial obstruction
Respiratory Exam: Causes of atelectasis
Intraluminal: Mucus, Foreign body, aspiration
Mural: Bronchial carcinoma
Extramural: ….
Respiratory Exam: DDx of haemoptysis
Malingering Pseudo-haemoptysis: GI source Infection: TB, Pneumonia. Infective bronchitis, bronchiectasis Infarction: PE Pulmonary odema: LVH, MS Vasculitis: SLE, Goodpastures
Respiratory Exam: DDx of pleural effusion
Transudate: HF, hypoalbuminuria, cirrhosis, nephrotic syndrome, hypothyroidism
Exudate: Infection, inflammation, neoplastic, pancreatitis
Empyema: Pus
Haemothorax: Blood
Chylothorax: Lymph
Respiratory Exam: How does Consolidation present? Mediastinal shift: Chest wall movement: Percussion: Breath sounds: Added sounds:
Mediastinal shift: None Chest wall movement: Decreased over affected area Percussion: Dull Breath sounds: Reduced (bronchial) Added sounds: Crackles
Respiratory Exam: How does Atelectasis present? Mediastinal shift: Chest wall movement: Percussion: Breath sounds: Added sounds:
Mediastinal shift: Towards side of collapse
Chest wall movement: Decreased over affected area
Percussion: Dull
Breath sounds: Absent/reduced
Added sounds: None
Respiratory Exam: How does Pleural effusion present? Mediastinal shift: Chest wall movement: Percussion: Breath sounds: Added sounds:
Mediastinal shift: Away from side of effusion in large effusions
Chest wall movement: Decreased over area affected
Percussion: Stony dull
Breath sounds: Absent over fluid, bronchial over upper border
Added sounds: nil
Respiratory Exam: How does Pneumothorax present? Mediastinal shift: Chest wall movement: Percussion: Breath sounds: Added sounds:
Mediastinal shift: Away from side fo Ptx Chest wall movement: Decreased over affected area Percussion: Hyperresonant Breath sounds: Absent/reduced Added sounds: nil
Respiratory Exam: How does ILD present? Mediastinal shift: Chest wall movement: Percussion: Breath sounds: Added sounds:
Mediastinal shift: Nil Chest wall movement:Decreased Symmetrically Percussion: Normal Breath sounds: Normal Added sounds: Crackles
Respiratory Exam: What is type one respiratory faiure and what are the commonest causes?
Low PaO2 but normal/low PaCO2
V/Q mismatch, hypoventilation, abnormal diffusion, right to left cardiac shunts.
V/Q mismatch: Pneumonia, PE, pulmonary oedema, asthma, emphysema, pulmonary fibrosis, ARDS
Respiratory Exam: What is type two respiratory failure and what are the commonest causes?
Low PaO2 and High PaCO2
Pulmonary problme: COPD, Pulmonary oedema, pneumonia
Mechanicl Problem: Chest wall trauma, muscular dystrophy, MND, Myasthenia gravis
Central: Opiate overdose, acute CNS disease
Respiratory Exam: List causes of dullness on percussion
Consolidation Effusion Atelectasis (presents same as lobectomy) Lobectomy/Pneumonectomy Raised hemidiaphragm Pleural thickening
Cranial Nerve Exam: Causes of opthalmoplegia
Myasthenia gravis Cranial Nerve Palsy Graves Disease Wernicke's Encephalopathy Progressive supranuclear palsy (vertical gaze)
Cranial Nerve Exam: Where does the lesion occur in internuclear opthalmoplegia?
Medial longitudinal fasciculus
Cranial Nerve Exam: What are the causes of Internuclear opthalmoplegia?
MS
Stroke
Cranial Nerve Exam: General causes of any cranial nerve palsy
Diabetes (microangiopathy of the vasa nervorum) Stroke MS Tumours Sarcoid SLE Vasculitis
Cranial Nerve Exam: Specific Causes of Cranial Nerve 1 (olfactory) palsies
Trauma (shearing of olfactory bulbs through cribriform plate)
Alzheimer’s and Parkison’s
Frontal lobe tumour (meningioma)
Meningitis
Cranial Nerve Exam: Specific Causes of Cranial Nerve 2 (optic) palsies
- Monocular
- Bitemporal hemianopia
- Homonymous hemianopia
- MS, GCA
- Lesion at optic chiasm: pituitary adenoma, suprasellar meningioma, craniopharyngioma
- Anything behind optic chiasm (stroke, tumour or abscess)
Cranial Nerve Exam: Causes of Relative Afferent Pupilllary defect
Optic Nerve disorder: Optic ischaemic neuropathy, optic neuritis, Optic nerve compression, unilateral glaucoma
Retinal Disorders: Central retinal artery/veins occlusion, severe diabetic retinopathy, retinal detachment, Infection (CMV/HSV), tumours (retinoblastoma/melanoma)
Cranial Nerve Exam: What would you see in a cranial nerve 3 palsy
Eye down and out position (unapposed lateral rectus and superior oblique)
Ptosis (levator palpebrae dysfunction)
Fixed Dilated pupil (parasympathetic nerve fibres from ciliary ganglion affected)
Do not always get all three signs. Often not all branches of the nerve affected
Cranial Nerve Exam: Causes of unilateral ptosis?
Cranial nerve III palsy
Horners syndrome
Congenital
Cranial Nerve Exam: Causes of bilateral ptosis?
Myasthenia gravis Myotonic dystrophy Bilateral Horners Neurosyphilus Congenital
Cranial Nerve Exam: Causes of cranial nerve 3 palsy
Location dependent!
Diabetes - vascular neuropathy
Demyelination
Midbrain: Infarction, haemorhage, tumour
Subarachnoid space: PCA aneurysm (will be painful!)
Superior orbital fissure (tumour, ICA artery [would also affect nerves in cavernous sinus]
Orbit: Tumour/trauma
Cranial Nerve Exam: Causes of cranial nerve 4 (trochlear) palsy
microvascular disease
Orbit trauma
Cranial Nerve Exam: CN5
What are the afferent and efferent branches of the corneal reflex?
Afferent: Opthalmic branch of the trigeminal
Efferent: Facial Nerve
Cranial Nerve Exam: CN7
What is the difference between an UMN and LMN 7th nerve lesion?
UMN: Sparing of the forehead due to bilateral facial representation at the level of the 7th nerve nuclei
LMN: All muscles of the face affect
Cranial Nerve Exam: Causes of LMN CN7 palsy?
Pons: Infarction, tumour, MS
Cerebellopontine angle (CN 6, 7 and 8 affected): Tumour (meningioma or acoustic neuroma)
Base of skull/parotid: Bells Palsy, Maligannt parotid tumour/parotid pathology, Herpes Zoster (Ramsay Hunt)
Cranial Nerve Exam: Causes of UMN CN7 palsy?
Stroke
Tumours
Cranial Nerve Exam: Causes of Bilateral facial nerve LMN weakness
Guillain Barre syndrome. Sarcoidosis, Myasthenia gravis, myotinic dystrophy
Cranial Nerve Exam: Features of bulbar palsy
Absent gag reflex
Wasted tongue + Fasciculations
Absent/normal Jaw Jerk
Nasal Speech
Cranial Nerve Exam: Features of pseudobulbar palsy
Increased/normal gag reflex
Spastic tongue
Jaw jerk increased
Spastic dysarthria
Cranial Nerve exam: Which way does the tongue deviate in a CNXII nerve lesion?
Toward the side of the lesion
Cranial Nerve exam: Which way does the uvula deviate in a CNX nerve
Away from side of lesion
Cranial Nerve Exam: Afferent and Efferent pathways of the gag reflex?
Afferent: Glossopharyngeal
Efferent: Vagus
Median Nerve Palsy
- Inspection
- Power
- Sensation
- Special Tests
- Inspection: Thenar wasting, carpel tunnel decompression scar
- Power: Thumb abduction
- Sensation: Lateral side of index finger
- Special Tests: Phalen’s, Allens
Radial Nerve Palsy
- Inspection
- Power
- Sensation
- Inspection: Forearm extensors and wrist drop
- Power: Wrist/MCP extension
- Sensation: Dorsal 1st interosseus space
Ulna Nerve Palsy
- Inspection
- Power
- Sensation
- Special Tests
- Inspection: Hypothenar wasting, interosseus wasting, elbow trauma
- Power: Index finger abduction
- Sensation: Medial side of little finger
- Special Tests: Fromonth’s
Rheum Hand: DDx of symmetrical polyarthritis
Rheumatoid arthritis
Osteoarthritis
Systemic conditions: SLE, Sarcoidosis etc
Rheum Hand: DDx of asymmetrical polyarthritis
Reactive arthritis
Psoriatic Arthritis
Systemic SLE, Sarcoid etc
Rheum Hand: DDx of oligoarthritis
Gout CPPD Psoriatic arthritis Reactive arthritis Ankylosing spondylitis OA
Rheuma Hand: DDx of monoarthritis
Septic arthritis Gout CPPD OA Trauma
XRay features of OA
Loss of joint space
Osteophytes
Subchrondral cysts
Subarticular sclerosis
Stoma: Features of iliostomy stoma and types/indications for one?
Site: RIF
Contents: Soft faeces
Opening: Spout to protect skin from enzymes
End Iliostomy: UC, FAP or Hirsprungs
Loop: De-function distal bowel (obstruction due to malignancy, anus (Crohn’s) or new distal anastamoses
Stoma: Features of colostomy stoma and types/indications for one?
Site: LIF
Contents: Hard faeces
Opening: Flush with skin
End: AP resection or hartmann’s
Loop: De-function distal bowel (obstruction due to malignancy, anus (Crohn’s) or new distal anastamoses
Stoma: Early complications?
High output ( dehydration, hypokalaemia) Peristomal inflammation Retraction Obstruction Ischaemia/Necrosis
Stoma: Late Complications?
Parastomal hernia
Prolapse
Fistula formation
Dermatitis
Cranial Nerve Exam: Presentation of a cranial nerve 4 lesion
Trochlear nerve palsies present
Cranial Nerve Exam: Presentation of a cranial nerve 6 lesion
Abducens Nerve palsies present with inability to abduct affected eye
Respiratory Exam: Causes of ILD
Idiopathic
Systemic disease: Rheumatoid arthritis, SLE, Sarcoidosis
Occupational exposure to asbestos
Drug toxicity: Amiodarone, methotrexate or radiotherapy
Lower Limb Neurology: Approach to foot drop?
?location of lesion
?What lesion is
Think anterior horn, L5 nerve root, lumbosacral plexus, sciatic nerve palsy, Common peroneal nerve palsy, Muscle.
Common peroneal nerve palsy: Ankle reflex intact, sensory loss between 1st and 2nd toes.
Sciatic nerve lesions: weak knee flexion, no ankle jerk, widespread sensory loss
L5 lesion: skdjdbadkjl
Neurological Exam: Signs of UMN lesion
Increased tone: Spasticity Decreased power Impaired coordination Increased reflexes (clonus present) Up-going plantars
Neurological Exam: Signs of LMN lesion
Muscle atropy, fasciculations Decreased tone Decreased power Coordination not impaired unless weakness Reduced or absent reflexes
Neurological Exam: What Hz tuning fork is used for webers and rinnes?
256Hz or 512Hz
Neurological Exam: What Hx tuning fork is used for vibration sensation
128Hz
Head and Neck: Describe the features of a neck lump you would comment on?
Sizze Shape Symmetry Surface Consistency Edges Fluctuance Pulsation Translumination
Head and Neck: DDx for mid-line neck mass
Thyroid THyroglossal cyst Lymph node Lipoma Sebaceous cyst Abscess
Head and Neck: DDx for anterior triangle neck mass
Thyroid, salivary gland, carotid artery aneurysm Carotid body tumour Branchial tumour Lymph node Lipoma Sebaceous cyst Abscess
Head and Neck: DDx for posterior triangle mass
cystic hygroma, lymph node, subclavian artery aneurysm , lipoma, abscess, sebaceous cyst
Head and Neck: DDx for a goitre
Multinodular goitre Hashimoto's thyroiditis Grave's Disease Iodine deficiency Acute thyroiditis (de Quer) Tumours Amyloid/sarcoid
Head and Neck: What are the classes of thyroid cancers and what markers are useful in these malignancies?
Differentiated: Papillary (85%) Follicular (12%)
Thyroglobulin proportional to amount of thyroid tissues so helpful in monitoring cancer burden and recurrence
Undifferentiated: ANaplastic
Medullary: Parafollicular (C) cells - CALCITONIN
Lower Limb Neuro: Causes of Bilateral leg weakness (paraparesis)? Acute: Spastic: Flaccid: Mixed UMN/LMN:
Acute: Acute cord compression, Cauda equina, Guillain-barre syndrome
Spastic: Sagital sinus lesion (meningioma), bilateral strokes, cord trauma, cord compression (epidural abscess, disc prolapse, spondylosis), intrinsic cord disease (tumour, Vascular myelopathy, MS, transverse myelitis)
Flaccid: Polio, Guillain-barre, lead poisening
Mixed: CMT
Lower Limb Neuro: Causes of Unilateral leg weakness?
Upper vs Lower motor neuron
UMN: Stroke, tumour, MS
LMN: Root lesion, Nerve lesion
Lower Limb Neuro: If on exam you find a spastic paraparesis, what should be included in the exam?
Assess for a sensory level on the thorax
Lower Limb Neuro, If on exam you find a flaccid paraparesis, what should you include on exam?
PR assessing for peri-anal sensation and sphincter tone
Peripheral Neurological exam: Causes of glove/stocking distribution sensory loss
Diabetes Mellitus Alcohol B12/folate deficiency Paraneoplastic syndrome Medications e.g. isoniazid
Neuro: What does a positive romberg’s test tell you?
Person has sensory ataxia
Can be due to dorsal column loss (B12/folate deficiency or MS) or sensory peripheral neuropathy
Diabetic Foot Exam: What are the key exam findings in assessing a diabetic foot? hat complications arise in diabetic feet?
Peripheral arterial disease Diabetic neuropathy (fine touch, vibration, joint-position sensation) + autonomic neuropathy
Ulcers and infections!
Cerebellar exam: Causes of cerebellar disease
Stroke Tumour MS Friedreich's Ataxia Alcohol abuse Thiamine deficiency (Wernicke's Encephalopathy) Anti-epileptic medication
Cerebellar exam: Classic signs of cerebellar lesion (DANISH)
Dysdiodochokinesis Ataxia (limb/trunk) Nystagmus Intention tremor Speech (slurred, staccato) Hypotonia
Cerebellar exam: Causes of cerebellar lesions
Stroke Tumour MS Congenital Friedreich's ataxia ALcohol abuse Thiamine deficiency Anti-epileptic medication
Extrapyramidal Exam: Causes of Parkinsonism
Idiopathic Parkinsons Disease Drug induced (Metacloperamide, lithium) Parkinsons plus syndromes (Progressive supranuclear palsy, corticobasilar degeneration, Multiple System atrophy) Vascular Parkinsons Lewy Body Dementia
Neuro Examination: Differential diagnosis of dysarthria, plus what features would you look for to confirm each?
Facial nerve palsy (facial muscle weakness)
Bulbar palsy (flaccid, wasted fasciculating tongue)
Pseudobulbar palsy (spastic, contracted tongue)
Myasthenia gravis
Cerebellar disease