Orthopedics Flashcards

1
Q

most common fracture due to osteoporosis

A

vertebral compression fracture

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2
Q

first line treatment for osteoporosis

A

bisphosphonates

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3
Q

bisphosphonate examples

A

alendronate, pamidronate, zoledronic acid

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4
Q

what tool is used to determine fracture risk

A

FRAX (fracture risk assessment tool)

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5
Q

bisphosphonate mechanism of action

A

inhibit osteoclast activity preventing bone resorption

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6
Q

what can be used as preventive measure for vertebral compression fractures as well as pain management

A

calcitonin

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7
Q

risk factors for osteoporosis

A

female, age, chronic steroid use, chronic PPI use, ETOH/tobacco use, family history

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8
Q

2nd line treatments for osteoporosis

A

SERMs (raloxifene), recombinant PTH (teriparatide), denosumab

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9
Q

how to take bisphosphonates

A

in the morning on an empty stomach, and remain upright 30 minutes after taking

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