Orthopedics Flashcards
most common fracture due to osteoporosis
vertebral compression fracture
first line treatment for osteoporosis
bisphosphonates
bisphosphonate examples
alendronate, pamidronate, zoledronic acid
what tool is used to determine fracture risk
FRAX (fracture risk assessment tool)
bisphosphonate mechanism of action
inhibit osteoclast activity preventing bone resorption
what can be used as preventive measure for vertebral compression fractures as well as pain management
calcitonin
risk factors for osteoporosis
female, age, chronic steroid use, chronic PPI use, ETOH/tobacco use, family history
2nd line treatments for osteoporosis
SERMs (raloxifene), recombinant PTH (teriparatide), denosumab
how to take bisphosphonates
in the morning on an empty stomach, and remain upright 30 minutes after taking